Results 11 to 20 of about 11,541 (257)

Diastereoselective synthesis of fused oxazolidines and highly substituted 1H-pyrrolo [2,1-c][1,4] oxazines via C–H functionalization [PDF]

, 2015
The first one pot protocol for the diastereoselective synthesis of oxazolo[2,3-c]isoquinoline was achieved by a metal-free, benzoic acid catalyzed reaction of 1,2,3,4-tetrahydroisoquinoline or trypoline with aldehydes under mild conditions via C–H, C–O ...
C. S. P. Kumar, K. B. Harsha, K. Mantelingu, K. Rangappa   +3 more
semanticscholar   +2 more sources

Self-Organization in Dilute Aqueous Solutions of Thermoresponsive Star-Shaped Six-Arm Poly-2-Alkyl-2-Oxazines and Poly-2-Alkyl-2-Oxazolines

Polymers, 2021
The behavior of star-shaped six-arm poly-2-alkyl-2-oxazines and poly-2-alkyl-2-oxazolines in aqueous solutions on heating was studied by light scattering, turbidimetry and microcalorimetry.
T. Kirila, A. Smirnova, V. Aseyev, A. Tenkovtsev, H. Tenhu, A. Filippov   +5 more
semanticscholar   +1 more source

Switchable Coumarins for Ratiometric pH Sensing

Frontiers in Materials, 2021
A fluorescent chromophore and a pH-sensitive heterocycle were integrated within a single covalent skeleton to generate four molecular switches with ratiometric fluorescence response.
Mercedes M. A. Mazza, Francesca Cardano, Francesca Cardano, Francesca Cardano, James D. Baker, Silvia Giordani, Silvia Giordani, Françisco M. Raymo   +7 more
doaj   +1 more source

Oxazinethione Derivatives as a Precursor to Pyrazolone and Pyrimidine Derivatives: Synthesis, Biological Activities, Molecular Modeling, ADME, and Molecular Dynamics Studies

Molecules, 2021
In this study, we used oxazinethione as a perfect precursor to synthesize new pyrimidine and pyrazole derivatives with potent biological activities. Biological activities were determined for all compounds against A. flavus, E. coli, S.
Magda H. Abdellattif, Mohd Shahbaaz, M. M. H. Arief, Mostafa A. Hussien   +3 more
doaj   +1 more source

Use of Phenyl Formate as a CO Surrogate for the Reductive Cyclization of Organic Nitro Compounds to Yield Different N-Heterocycles: Avoiding the Use of Autoclaves and Pressurized Gases

Chemistry Proceedings, 2022
The reductive cyclization of different organic nitro compounds by carbon monoxide, catalyzed by transition metal complexes, is a very efficient and clean strategy for the synthesis of many N-heterocycles.
Fabio Ragaini, Francesco Ferretti, Manar Ahmed Fouad   +2 more
doaj   +1 more source

Cycloaddition of 4-Acyl-1H-pyrrole-2,3-diones Fused at [e]-Side and Cyanamides: Divergent Approach to 4H-1,3-Oxazines

Molecules, 2022
4-Acyl-1H-pyrrole-2,3-diones fused at [e]-side with a heterocyclic moiety are suitable platforms for the development of a hetero-Diels–Alder-reaction-based, diversity-oriented approaches to series of skeletally diverse heterocycles.
Ekaterina E. Khramtsova, Aleksandr D. Krainov, Maksim V. Dmitriev, Andrey N. Maslivets   +3 more
doaj   +1 more source

Synthesis, crystal structure and Hirshfeld surface analysis of 1,7-dimethyl-5a,6,11a,12-tetrahydrobenzo[b]benzo[5,6][1,4]oxazino[2,3-e][1,4]oxazine

Acta Crystallographica Section E: Crystallographic Communications, 2020
Molecules of the title compound, C16H16N2O2, occupy special positions on the twofold rotation axes. The heterocyclic ring adopts a slightly twisted envelope conformation with one of the two junction carbon atoms as the flap.
Emine Berrin Çınar, Semanur Yeşilbağ, Onur Erman Doğan, Erbil Ağar, Necmi Dege, Eiad Saif   +5 more
doaj   +1 more source

SUBSTITUTED 4-NITROSOPYRAZOLES IN THE DIELS-ALDER REACTION

Siberian Journal of Life Sciences and Agriculture, 2021
Background. 4-Nitrosopyrazoles have become widespread in the pharmaceutical industry and in chemistry due to their high reactivity and biological activity. However, the interaction of 3,5-substituted 4-nitroso-1H-pyrazoles with diene hydrocarbons has not
Darya S. Volkova, Arkadiy A. Popov, Evgeny V. Root, Alexey A. Kukushkin, George A. Suboch   +4 more
doaj   +1 more source

1,4-Oxazine

Chemical Communications, 2013
The fundamental heterocyclic compound 1,4-oxazine has been generated using FVP. It is the first parent heterocycle among all the possible isomeric oxazines, thiazines and their heavier atom analogues to be characterised spectroscopically, and is shown to exist in solution entirely as the 4H-isomer.
Aitken, R Alan, Aitken, Kati Marianne, Carruthers, Phillip G, Jean, Marc-Alexandre, Slawin, Alexandra Martha Zoya   +4 more
openaire   +6 more sources

N-Substituted Pyrido-1,4-Oxazin-3-Ones Induce Apoptosis of Hepatocellular Carcinoma Cells by Targeting NF-κB Signaling Pathway

Frontiers in Pharmacology, 2018
Hepatocellular carcinoma (HCC) is a fatal disease and ranked fifth in cancer related mortality. Persistent activation of NF-κB is responsible for the oncogenesis, metastasis, tumor evasion, anti-apoptosis, angiogenesis and proliferation in HCC. Therefore,
Chakrabhavi Dhananjaya Mohan, Hanumantharayappa Bharathkumar, Dukanya, Shobith Rangappa, Muthu K. Shanmugam, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Tahani Awad Alahmadi, Atanu Bhattacharjee, Peter E. Lobie, Amudha Deivasigamani, Kam Man Hui, Gautam Sethi, Basappa, Basappa, Kanchugarakoppal S. Rangappa, Alan Prem Kumar, Alan Prem Kumar, Alan Prem Kumar, Alan Prem Kumar   +19 more
doaj   +1 more source