Results 61 to 70 of about 11,863 (256)
Copper Catalyzed Inverse Electron Demand [4+2] Cycloaddition for the Synthesis of Oxazines [PDF]
Weiguang Yang +7 more
openalex +1 more source
ABSTRACT The β‐secretase BACE1 (β‐site amyloid precursor (APP) cleaving enzyme 1) is a major drug target for Alzheimer's disease (AD), as it catalyzes the first step in amyloid β (Aβ) generation, but has additional substrates and functions, in particular in the brain.
Sarah K. Tschirner +7 more
wiley +1 more source
Synthesis of Substituted Pyrido-oxazine through Tandem SN2 and SNAr Reaction
Pyrido-oxazine derivatives have been synthesized by employing tandem SN2 and SNAr reaction between 2,4,6-tribromo-3-(2-bromoethoxy)pyridine or 2,4,6-tribromo-3-(3-bromopropoxy)pyridine and a variety of primary amines. Moderate to good regioselectivity in
Mosim Amin Pathan, Faiz Ahmed Khan
doaj +1 more source
Catalytic Strategies for Amide‐Based Michael Additions: Advances and Perspectives
The Michael addition is a cornerstone transformation in organic synthesis, enabling efficient C–C and C–heteroatom bond formation. Traditionally, α,β‐unsaturated carbonyl compounds such as enones and esters have dominated as Michael acceptors, whereas α,β‐unsaturated amides remain underutilized due to their strong resonance stabilization and low ...
Muhammad Naufal +6 more
wiley +1 more source
Transition Metal-Free Cascade Cyclization of Epoxy-Ynamides: To Go for 1,3-Oxazines or 1,4-Oxazines?
An approach to both 1,3- and 1,4-oxazines is developed by the cascade cyclization of epoxy ynamides under transition metal-free conditions. Thus, while 1,3-oxazines are obtained in a regio- and stereoselective manner by using base, cyclization of epoxy ...
A. Siva Kumari, A. Siva Reddy, K. Swamy
semanticscholar +1 more source
ABSTRACT This study characterised the volatile compounds in flatbreads prepared from red non‐tannin sorghum flour, cassava starch, whole and dehulled red and white cowpea flours and composite flours (30% cowpea flour and varying combinations of cassava starch and sorghum flour).
Rita Dankwa +5 more
wiley +1 more source
A microwave-assisted, environmentally benign green protocol for the synthesis of functionalized (Z)-3-(2-oxo-2-phenylethylidene)-3, 4-dihydro-2H-benzo[b][1,4]oxazin-2-ones 11a-n in excellent yields (upto 97%) and (Z)-3-(2-oxo-2-phenylethylidene)-3,4 ...
Vashundhra Sharma +8 more
doaj +1 more source
Racemic chiral O,N-heterocycles containing 2-arylchroman or 2-aryl-2H-chromene subunit condensed with morpholine, thiazole, or pyrrole moieties at the C-3-C-4 bond were synthesized with various substitution patterns of the aryl group by the cyclization ...
Ádám Szappanos +10 more
doaj +1 more source
The illustration depicts the improvement in the mechanical and ablative properties of polybenzoxazine composites according to their alumina particle content. ABSTRACT The aerospace industry is seeking a replacement of toxic phenolics to use in ablative materials. One of the most promising candidates is polybenzoxazine materials because of their extreme
İ. Egemen Küçük +2 more
wiley +1 more source
Applications of QSPR and Machine Learning in Molecular Photonics
Quantitative structureproperty relationships (QSPR) and machine learning (ML) are transforming photochemistry by enabling pre‐synthetic screening of photoactive molecules. This review outlines advances in data‐driven discovery of optical materials and functional dyes, identifies effective descriptors and models for photophysical processes, and provides
Andrey A. Buglak +2 more
wiley +1 more source

