Results 61 to 70 of about 7,946 (266)

A Synthetic Approach to Pyrazolopyranopyrimidinones and Pyrazolopyranooxazinones as Antimicrobial Agents

open access: yesJournal of Chemistry, 2016
The hitherto unknown 6-amino-4-(2-chloro-5-nitrophenyl)-3-methyl-1,4-dihydropyrano[2,3-c] pyrazole-5-carbonitrile 1a was synthesized. Both 1a and its 2,4 dichlorophenyl derivative 1b were utilized as building blocks for the preparation of novel class of ...
A. K. Elziaty   +4 more
doaj   +1 more source

Stereoselective Synthesis and Cytoselective Toxicity of Monoterpene-Fused 2-Imino-1,3-thiazines

open access: yesMolecules, 2014
Starting from pinane-, apopinane- and carane-based 1,3-amino alcohols obtained from monoterpene-based β-amino acids, a library of monoterpene-fused 2-imino-1,3-thiazines as main products and 2-thioxo-1,3-oxazines as side-products were prepared via two ...
Zsolt Szakonyi   +3 more
doaj   +1 more source

Efficient synthesis of 1,3-naphtoxazine derivatives using reusable magnetic catalyst (GO-Fe3O4–Ti(IV)): anticonvulsant evaluation and computational studies

open access: yesBMC Chemistry, 2022
A series of 2-aryl/alkyl-2,3-dihydro-1H-naphtho[1,2-e][1,3]oxazines (S 1 –S 11 ) were synthesized with an eco-friendly and recoverable nanocatalyst (GO-Fe3O4–Ti(IV)) as an efficient magnetic composite. The new nanocatalyst was characterized by FT-IR, XRD
Soghra Khabnadideh   +8 more
doaj   +1 more source

Vinyl Dihydropyrans and Dihydrooxazines: Cyclizations of Catalytic Ruthenium Carbenes Derived from Alkynals and Alkynones [PDF]

open access: yes, 2014
NOTICE: This is the peer reviewed version of the following article: Cambeiro, F., López, S., Varela, J. A., Saá, C. (2014). Vinyl Dihydropyrans and Dihydrooxazines: Cyclizations of Catalytic Ruthenium Carbenes Derived from Alkynals and Alkynones.
Cambeiro Cambeiro, Fermín   +3 more
core   +1 more source

Chemically- and photo-convertible dyes for fluorescence detection of biomolecules [PDF]

open access: yes, 2023
Further progress in fluorescence microscopy and nanoscopy depends, among other factors, on the ease of detection, analysis, and selective imaging of bioconjugates prepared from fluorescent dyes with reactive groups and biomolecules.
Savicheva, Elizaveta
core   +1 more source

Overestimation of Automated Platelet Counts by Blast Fragments in Acute Hypercellular Leukemias: A Retrospective Study Comparing Impedance, Optical (PLT‐O), Fluorescent (PLT‐F), and CD41/CD61 Flow Cytometry Methods

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Acute leukemias with hyperleukocytosis (> 100 × 109/L) can produce cytoplasmic blast fragments that interfere with platelet counts, notably in impedance‐based methods, potentially masking severe thrombocytopenia and increasing hemorrhagic risk.
Victor Bobée   +10 more
wiley   +1 more source

Scaffold hopping approaches for the exploration of herbicidally active compounds inhibiting Acyl‐ACP Thioesterase

open access: yesPest Management Science, Volume 81, Issue 5, Page 2617-2634, May 2025.
The work presented herein details the scaffold hopping efforts to find novel herbicidal lead structures that target acyl‐ACP thioesterase. This resulted in the discovery of the new dihydropyranopyridine structural class that exhibits good in vitro inhibition of acyl‐ACP coupled with strong herbicidal activity in greenhouse trials.
Tyler Fahrenhorst‐Jones   +12 more
wiley   +1 more source

Synthesis of Substituted Pyrido-oxazine through Tandem SN2 and SNAr Reaction

open access: yesSynOpen, 2018
Pyrido-oxazine derivatives have been synthesized by employing tandem SN2 and SNAr reaction between 2,4,6-tribromo-3-(2-bromoethoxy)pyridine or 2,4,6-tribromo-3-(3-bromopropoxy)pyridine and a variety of primary amines. Moderate to good regioselectivity in
Mosim Amin Pathan, Faiz Ahmed Khan
doaj   +1 more source

Novel Reactions of Donor-Acceptor Cyclopropanes, and Diels-Alder Approach Towards Fargesine and Fumimycin [PDF]

open access: yes, 2016
The first chapter of this thesis consists of two related projects that explore novel reactivity of donor-acceptor cyclopropanes, specifically 2-substituted cyclopropane 1,1-diesters.
Kyriacou, Polydoros
core   +1 more source

Nanoparticles Combining Host‐Directed Therapeutics and Antibiotics to Boost Bacterial Killing and Overall Survival of Zebrafish Embryos Infected with Mycobacterium Marinum

open access: yesAdvanced Therapeutics, Volume 8, Issue 4, April 2025.
This study investigates the combination of host‐directed therapeutics (HDT) with antibiotics in a single polymeric micelle based on polypept(o)ides for the therapy of Mycobacterium tuberculosis (Mtb) and ‐marinum (Mm) infections. When the HDT and antibiotic are co‐encapsulated, it significantly reduces bacterial burden in cells and improves overall ...
Gabriela Schäfer   +5 more
wiley   +1 more source

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