Results 11 to 20 of about 18,651 (251)

Oxazole and Thiazole Analogs of Sulindac for Cancer Prevention [PDF]

, 2018
Aim: Experimental and epidemiological studies and clinical trials suggest that nonsteroidal anti-inflammatory drugs possess antitumor potential. Sulindac, a widely used nonsteroidal anti-inflammatory drug, can prevent adenomatous colorectal polyps and ...
Bini Mathew, Judith V. Hobrath, Michele Connelly, R. Kiplin Guy, Robert C. Reynolds   +4 more
openalex   +5 more sources

A study of cell membranes in nasal epithelial cells from patients with chronic rhinosinusitis with nasal polyps by means of a fluorescent probe [PDF]

, 2009
Aim. To assess the state of membranes in nasal epithelial cells obtained from the patients with chronic rhinosinusitis with nasal polyps (CRSwNP) with the help of the fluorescent probe 2-(2ʹ-ОН-phenyl)-5-phenyl-1,3-oxazole. Methods. The state of membrane
Onishchenko, A. I., Tkachenko, A. S., Nakonechna, O. A., Korniyenko, Y. M., Ryshchenko, I. M., Tsygankov, A. V., Posokhov, Y. O.   +6 more
core   +2 more sources

Recent Advances in the Synthesis of Oxazole-Based Molecules via van Leusen Oxazole Synthesis

Molecules, 2020
Oxazole compounds, including one nitrogen atom and one oxygen atom in a five-membered heterocyclic ring, are present in various biological activities. Due to binding with a widespread spectrum of receptors and enzymes easily in biological systems through
Xunan Zheng, Wei Liu, Dawei Zhang
doaj   +1 more source

Synthesis of Pyridoxine-Derived Dimethylpyridinols Fused with Aminooxazole, Aminoimidazole, and Aminopyrrole

Molecules, 2022
Described in this paper are studies on the preparation of three classes of dimethylpyridinols derived from pyridoxine fused with aminooxazole, aminoimidazole, and aminopyrrole.
Bhuwan Prasad Awasthi, Hyunji Lee, Byeong-Seon Jeong   +2 more
doaj   +1 more source

Synthetic Strategies to Access Fluorinated Azoles. [PDF]

European J Org Chem
This review highlights recent synthetic strategies for introducing fluorine groups (mono‐, di‐, and trifluoromethylation) into 11 major azole classes, identifying research gaps to inform future innovations in materials science, medicinal chemistry, and biomedical research.
El-Gaber MKA, Djugovski M, Huang TY, Adhikari S, Roy S.   +4 more
europepmc   +2 more sources

Suzuki Coupling of Oxazoles [PDF]

Organic Letters, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Flegeau, Emmanuel Ferrer, Popkin, Matthew E., Greaney, Michael F.   +2 more
openaire   +3 more sources

Alkoxyallene‐Based LANCA Three‐Component Synthesis of 1,2‐Diketones, Quinoxalines, and Unique Isoindenone Dimers and a Computational Study of the Isoindenone Dimerization [PDF]

, 2020
A series of β‐alkoxy‐β‐ketoenamides was prepared by the well‐established LANCA three‐component reaction of lithiated 1‐(2‐trimethylsilylethoxy)‐substituted allenes, nitriles, and α,β‐unsaturated carboxylic acids.
Bera M. K., Holland J. M., Lechel T., Lechel T., Zimmer R., Zimmer R., Zimmer R.   +6 more
core   +1 more source

Crystal structure and Hirshfeld surface analysis of (3S,3aR,6aS)-3-(1,3-diphenyl-1H-pyrazol-4-yl)-5-(4-methoxyphenyl)-2-phenyl-3,3a,4,5,6,6a-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione

Acta Crystallographica Section E: Crystallographic Communications, 2021
In the title compound, C33H26N4O4, the two fused five-membered rings and their N-bound aromatic substituents form a pincer-like motif. The relative conformations about the three chiral carbon atoms are established.
Shaaban K. Mohamed, Awad I. Said, Joel T. Mague, Talaat I. El-Emary, Mehmet Akkurt, Sahar M. I. Elgarhy   +5 more
doaj   +1 more source

A modified approach for the synthesis of biologically relevant 5-substituted-2-N-aryl-1,3-oxazole derivatives in mild conditions

Journal of Taibah University for Science, 2020
We herein report a modified approach for the synthesis of some pharmacologically relevant oxazole derivatives linked with amides under mild conditions.
R. Udhayasurian, K. Sivakumar, Ayyiliath M. Sajith, Muthipeedika Nibin Joy   +3 more
doaj   +1 more source

A comprehensive review on biological activities of oxazole derivatives

BMC Chemistry, 2019
The utility of oxazole as intermediates for the synthesis of new chemical entities in medicinal chemistry have been increased in the past few years. Oxazole is an important heterocyclic nucleus having a wide spectrum of biological activities which drew ...
Saloni Kakkar, Balasubramanian Narasimhan   +1 more
doaj   +1 more source