Results 31 to 40 of about 6,381 (215)

Pharmacokinetic Drug Interactions of Antimicrobial Drugs: A Systematic Review on Oxazolidinones, Rifamycines, Macrolides, Fluoroquinolones, and Beta-Lactams

open access: yesPharmaceutics, 2011
Like any other drug, antimicrobial drugs are prone to pharmacokinetic drug interactions. These drug interactions are a major concern in clinical practice as they may have an effect on efficacy and toxicity.
Jan-Willem C. Alffenaar   +4 more
doaj   +1 more source

Evidence Associated with the Use of Oxazolidinones for the Treatment of Skin and Skin Structure Infections: A Retrospective Study

open access: yesActa Médica Portuguesa, 2019
Introduction: Skin and skin structure infections are an increasing cause of hospitalization. Although mortality is relatively low, skin and skin structure infections are associated with prolonged hospital length of stay and high costs.
João Gonçalves-Pereira   +4 more
doaj   +1 more source

Comparative study of in vitro activity of tedizolid and linezolid against Mycobacterium avium complex.

open access: yesJournal of Global Antimicrobial Resistance, 2022
Objectives: The aim of this study is to compare the in vitro activity and minimal inhibitory concentration (MIC) distributions of tedizolid and linezolid against Mycobacterium avium complex (MAC) strains using a reference broth microdilution assay and a ...
Eduardo Marfil   +3 more
doaj   +1 more source

Ionic Liquid-Promoted Three-Component Domino Reaction of Propargyl Alcohols, Carbon Dioxide and 2-Aminoethanols: A Thermodynamically Favorable Synthesis of 2-Oxazolidinones

open access: yesMolecules, 2018
To circumvent the thermodynamic limitation of the synthesis of oxazolidinones starting from 2-aminoethanols and CO2 and realize incorporation CO2 under atmospheric pressure, a protic ionic liquid-facilitated three-component reaction of propargyl alcohols,
Shumei Xia   +4 more
doaj   +1 more source

Cu(I)/Ionic Liquids Promote the Conversion of Carbon Dioxide into Oxazolidinones at Room Temperature

open access: yesMolecules, 2019
Recently, the efficient chemical fixation of carbon dioxide (CO2) into high value chemicals without using noble metal catalysts has become extremely appealing from the viewpoint of sustainable chemistry.
Jikuan Qiu   +6 more
doaj   +1 more source

3-Aryl-2-oxazolidinones through the Palladium-Catalyzed N-Arylation of 2-Oxazolidinones

open access: yes, 2016
3-Aryl-2-oxazolidinones are obtained in good yields through the palladium-catalyzed N-arylation of 2-oxazolidinones with aryl bromides.
Antonella Goggiamani (1565935)   +3 more
core   +1 more source

Comparison of the in vitro activity of linezolid, tedizolid, sutezolid, and delpazolid against rapidly growing mycobacteria isolated in Beijing, China

open access: yesInternational Journal of Infectious Diseases, 2021
Background: The natural resistance of rapidly growing mycobacteria (RGM) to multiple antibiotics renders the treatment of the infections caused less successful.
Shu’an Wen   +9 more
doaj   +1 more source

Investigational and Experimental Drugs for Community-Acquired Pneumonia: the Current Evidence

open access: yesJournal of Experimental Pharmacology, 2020
Juilia Sellarès-Nadal, Joaquin Burgos, Vicenç Falcó, Benito Almirante Infectious Diseases Department, Hospital Universitari Vall d’Hebron, Autonomous University of Barcelona, Barcelona, SpainCorrespondence: Benito ...
Sellarès-Nadal J   +3 more
doaj  

Response to Emerging Infection Leading to Outbreak of Linezolid-Resistant Enterococci

open access: yesEmerging Infectious Diseases, 2007
Linezolid was approved in 2000 for treatment of gram-positive coccal infections. We performed a case-control study during a hospital outbreak of linezolid-resistant enterococci (LRE) infections, comparing cases of LRE infection (cases) with linezolid ...
Marion A. Kainer   +9 more
doaj   +1 more source

N-Acylation of Oxazolidinones via Aerobic Oxidative NHC Catalysis

open access: yes, 2018
In the ongoing quest to find alternatives to atom un-economical and forcing conditions in acylation reactions, aerobic oxidative NHC catalysis has emerged as a method to convert aldehydes to potent acylating reagents.
Henrik Sundén (1399444)   +15 more
core   +1 more source

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