Results 11 to 20 of about 2,355 (106)

Antimicrobial Effect of Oxazolidinones and Its Synergistic Effect with Bedaquiline Against Mycobacterium abscessus Complex

Infection and Drug Resistance, 2023
Tianhui Gao,1,* Cong Yao,1,* Yuanyuan Shang,1 Renchun Su,1 Xuxia Zhang,1 Weicong Ren,1 Shanshan Li,1 Wei Shu,2 Yu Pang,1 Qi Li2 1Department of Bacteriology and Immunology, Beijing Key Laboratory for Drug-Resistant Tuberculosis Research, Beijing ...
Gao T, Yao C, Shang Y, Su R, Zhang X, Ren W, Li S, Shu W, Pang Y, Li Q   +9 more
doaj   +1 more source

New Oxazolidinones for Tuberculosis: Are Novel Treatments on the Horizon?

Pharmaceutics
Multidrug-resistant tuberculosis (MDR-TB) is a global health concern. Standard treatment involves the use of linezolid, a repurposed oxazolidinone. It is associated with severe adverse effects, including myelosuppression and mitochondrial toxicity.
Ricky Hao Chen, Andrew Burke, Jin-Gun Cho, Jan-Willem Alffenaar, Lina Davies Forsman   +4 more
doaj   +3 more sources

A Critical Review of Oxazolidinones: An Alternative or Replacement for Glycopeptides and Streptogramins? [PDF]

Canadian Journal of Infectious Diseases, 2001
OBJECTIVE: To review the available data on the oxazolidinones linezolid and eperezolid.
George G Zhanel, Coleen Schroeder, Lavern Vercaigne, Alfred S Gin, John Embil, Daryl J Hoban   +5 more
doaj   +2 more sources

Palladium-catalyzed formation of oxazolidinones from biscarbamates: a mechanistic study [PDF]

Beilstein Journal of Organic Chemistry, 2011
Oxazolidinones can be synthesized starting from cyclic biscarbamates via a palladium-catalyzed reaction. To test the proposed mechanism of this reaction, first, bicyclonorcarene endoperoxides derived from cyano and carbomethoxy cycloheptatrienes were ...
Benan Kilbas, Metin Balci
doaj   +2 more sources

Ligand-Free Ullmann-Type Arylation of Oxazolidinones by Diaryliodonium Salts [PDF]

, 2022
The arylation of azaheterocycles can be considered as one of the most important processes for the preparation of various biologically active compounds.
Natalia , Soldatova, Pavel, Postnikov, Ekaterina, Podrezova, Artem , Rogachev, Mekhman , Yusubov, Alina , Okhina, Andreas, Kirschning, Sergey , Baykov   +7 more
core   +2 more sources

oxazolidinones

, 2022
Archive of oxazolidinones containing sub-folders named after each compound and its net charge. Every compound's folder contains a total of 20 files distributed into three sub-directories reporting QM (QM/), FF (FF/), and MD (MD ...
Giuliano Malloci (2060875), Silvia Gervasoni (6169202), Andrea Bosin (6743129), Helen I. Zgurskaya (3093648), Attilio Vittorio Vargiu (2358538), Paolo Ruggerone (247673)   +5 more
core   +1 more source

N-Acylation of Oxazolidinones via Aerobic Oxidative NHC Catalysis [PDF]

, 2018
In the ongoing quest to find alternatives to atom un-economical and forcing conditions in acylation reactions, aerobic oxidative NHC catalysis has emerged as a method to convert aldehydes to potent acylating reagents.
Henrik Sundén (1399444), Anton, Axelsson, Sund\ue9n, Henrik, Linda, Ta, Axelsson, Anton,, Linda Ta (257721), Henrik Sundén (5214749), Anton Axelsson, Anton Axelsson (5215523), Henrik, Sundén, Ta, Linda,, Linda Ta, Sundén, Henrik,, Ta, Linda, Axelsson, Anton, Henrik Sundén   +15 more
core   +1 more source

Synthesis of oxazolidinones from N-aryl-carbamate and epichlorohydrin under mild conditions [PDF]

, 2022
The reaction conditions for an enantiospecific synthesis of various N-aryl-oxazolidinones from N-aryl-carbamates and (R) or (S) epichlorohydrin were optimized.
Buscemi S., Moreno L. M., Marzullo P., Palumbo Piccionello A., Insuasty B.   +4 more
core   +1 more source

Synthesis of Oxazolidinones by a Hypervalent Iodine Mediated Cyclization of N‐Allylcarbamates [PDF]

, 2021
The preparation of oxazolidinones by the hypervalent iodine mediated cyclization of allylcarbamates is described. A versatile range of substrates can be converted into substituted oxazolidinones primed for further transformations.
Lo, Pui Kin Tony, Moran, Wesley, Rodriguez, Arantxa, Arantxa Rodríguez, Wesley J. Moran, Das, Mirdyul, Pui Kin Tony Lo, Mirdyul Das, Moran, Wesley J.   +8 more
core   +1 more source

Systems to Access 5‐Aryl‐2‐Oxazolidinones: Catalyst‐Free Synthesis Under Ambient Conditions [PDF]

, 2020
The development of sustainable synthetic routes to access valuable oxazolidinones via CO2 fixation is an active research area, and the aziridine/carbon dioxide coupling has aroused a considerable interest. This reaction features a high activation barrier
Pampaloni G., Gianluca, Ciancaleoni, Zacchini S., Stefano Zacchini, Gianluca Ciancaleoni, Guido Pampaloni, Emanuele, Antico, Emanuele Antico, Ciancaleoni G., Giulio, Bresciani, Bresciani G., Stefano, Zacchini, Fabio, Marchetti, Marchetti F., Fabio Marchetti, Giulio Bresciani, Guido, Pampaloni, Antico E.   +17 more
core   +3 more sources