Results 31 to 40 of about 241,502 (298)
Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants☆
Archives of Biochemistry and Biophysics, 2017 The Kelch-like ECH associated protein 1 (Keap1) is a component of a Cullin3-based Cullin-RING E3 ubiquitin ligase (CRL) multisubunit protein complex.
A. Dinkova-Kostova +2 more
semanticscholar +1 more source
International Journal of Polymer Science, 2018 Conductive polymer, polypyrrole (PPy), was synthesized by chemical oxidative polymerization technique for a period of four hours at room temperature using pyrrole monomer (mPPy) in aqueous solution.
A. Yussuf +3 more
semanticscholar +1 more source
Role of Protein Carbonylation in Skeletal Muscle Mass Loss Associated with Chronic Conditions
Proteomes, 2016 Muscle dysfunction, characterized by a reductive remodeling of muscle fibers, is a common systemic manifestation in highly prevalent conditions such as chronic heart failure (CHF), chronic obstructive pulmonary disease (COPD), cancer cachexia, and ...
Esther Barreiro
doaj +1 more source
Local and Regional Contributions to Tropospheric Ozone Concentrations
Atmosphere, 2023 The Wasatch Front in Utah, USA is currently a non-attainment area for ozone according to the Environmental Protection Agency’s (EPA) National Ambient Air Quality Standards (NAAQS). Nitrogen oxides (NOx = NO2 + NO) and volatile organic compounds (VOCs) in
Callum E. Flowerday +2 more
doaj +1 more source
Redox Signaling by Reactive Electrophiles and Oxidants.
Chemical Reviews, 2018 The concept of cell signaling in the context of nonenzyme-assisted protein modifications by reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely complex topic that has been approached from numerous different and ...
Saba Parvez +3 more
semanticscholar +1 more source
Antioxidants, 2023 Oxidative stress, the alteration of mitochondrial function, and the neurovascular unit (NVU), play a role in Amyotrophic Lateral Sclerosis (ALS) pathogenesis.
Elena Grossini +5 more
doaj +1 more source
Metabolites, 2023 The seed extract of Foeniculum vulgare (FV) was used for the preparation of a nanosuspension (NS) with an enhanced bioavailability of phytoconstituents. Subsequently, it was employed as a potent source of polyphenols, such as quercetin and kaempferol, to
Majed A. Bajaber +10 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Oxidative Shielding or Oxidative Stress? [PDF]
The Journal of Pharmacology and Experimental Therapeutics, 2012 In this review I report evidence that the mainstream field of oxidative damage biology has been running fast in the wrong direction for more than 50 years. Reactive oxygen species (ROS) and chronic oxidative changes in membrane lipids and proteins found in many chronic diseases are not the result of accidental damage.
openaire +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source