Oxidative phosphorylation in bone cells [PDF]
Bone Reports, 2023The role of energy metabolism in bone cells is an active field of investigation. Bone cells are metabolically very active and require high levels of energy in the form of adenosine triphosphate (ATP) to support their function.
Elena Sabini+4 more
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A first--order irreversible thermodynamic approach to a simple energy converter [PDF]
Physical Review E 77, 011123 (2008), 2007Several authors have shown that dissipative thermal cycle models based on Finite-Time Thermodynamics exhibit loop-shaped curves of power output versus efficiency, such as it occurs with actual dissipative thermal engines. Within the context of First-Order Irreversible Thermodynamics (FOIT), in this work we show that for an energy converter consisting ...
A. L. Lehninger+16 more
arxiv +3 more sources
Mitochondrial Oxidative Phosphorylation in Viral Infections [PDF]
Viruses, 2023Mitochondria have been identified as the “powerhouse” of the cell, generating the cellular energy, ATP, for almost seven decades. Research over time has uncovered a multifaceted role of the mitochondrion in processes such as cellular stress signaling ...
Neeraja Purandare+3 more
doaj +2 more sources
Oxidative Phosphorylation as a Predictive Biomarker of Oxaliplatin Response in Colorectal Cancer [PDF]
BiomoleculesOxaliplatin is successfully used on advanced colorectal cancer to eradicate micro-metastasis, whereas its benefits in the early stages of colorectal cancer remains controversial since approximately 30% of patients experience unexpected relapses.
Toni Martinez-Bernabe+3 more
doaj +2 more sources
Reduced coupling of oxidative phosphorylation in vivo precedes electron transport chain defects due to mild oxidative stress in mice. [PDF]
PLoS ONE, 2011Oxidative stress and mitochondrial function are at the core of many degenerative conditions. However, the interaction between oxidative stress and in vivo mitochondrial function is unclear.
Michael P Siegel+8 more
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The mitochondrial electron transport chain utilizes a series of electron transfer reactions to generate cellular ATP through oxidative phosphorylation.
Deirdre Nolfi-Donegan+2 more
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Xenobiotics that affect oxidative phosphorylation alter differentiation of human adipose-derived stem cells at concentrations that are found in human blood [PDF]
Disease Models & Mechanisms, 2015Adipogenesis is accompanied by differentiation of adipose tissue-derived stem cells to adipocytes. As part of this differentiation, biogenesis of the oxidative phosphorylation system occurs.
Laura Llobet+4 more
doaj +4 more sources
Oxidative Phosphorylation Impairment by DDT and DDE
Frontiers in Endocrinology, 2019There is increasing evidence supporting the characterization of the pesticide DDT and its metabolite, DDE, as obesogens and metabolic disruptors. Elucidating the mechanism is critical to understanding whether the association of DDT and DDE with obesity ...
Sarah E. Elmore, Michele A. La Merrill
doaj +2 more sources
Oxidative phosphorylation in HIV-1 infection: impacts on cellular metabolism and immune function [PDF]
Frontiers in ImmunologyHuman Immunodeficiency Virus Type 1 (HIV-1) presents significant challenges to the immune system, predominantly characterized by CD4+ T cell depletion, leading to Acquired Immunodeficiency Syndrome (AIDS).
Natalia Rodriguez Rodriguez+6 more
doaj +2 more sources
Targeting oxidative phosphorylation as an approach for the treatment of ovarian cancer
Frontiers in Oncology, 2022Ovarian cancer is an aggressive tumor that remains to be the most lethal gynecological malignancy in women. Metabolic adaptation is an emerging hallmark of tumors.
Yinjie Wu+5 more
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