Results 1 to 10 of about 3,752,495 (242)

Oxidative phosphorylation [PDF]

open access: greenBiochemical Journal, 1953
H. A. Krebs   +4 more
openalex   +3 more sources

RESPIRATORY ENZYMES IN OXIDATIVE PHOSPHORYLATION

open access: hybridJournal of Biological Chemistry, 1955
Britton Chance, G. R. Williams
openalex   +3 more sources

Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials

open access: yesNature Network Boston, 2023
Although targeting oxidative phosphorylation (OXPHOS) is a rational anticancer strategy, clinical benefit with OXPHOS inhibitors has yet to be achieved. Here we advanced IACS-010759, a highly potent and selective small-molecule complex I inhibitor, into ...
T. Yap   +48 more
semanticscholar   +1 more source

Elevated microglial oxidative phosphorylation and phagocytosis stimulate post-stroke brain remodeling and cognitive function recovery in mice

open access: yesCommunications Biology, 2022
New research shows that disease-associated microglia in neurodegenerative brains present features of elevated phagocytosis, lysosomal functions, and lipid metabolism, which benefit brain repair.
Shanshan Song   +10 more
semanticscholar   +1 more source

The Effect of Oxidative Phosphorylation on Cancer Drug Resistance

open access: yesCancers, 2022
Simple Summary Drug therapy is an important treatment for cancer patients; however, drug resistance severely affects the survival time and quality of life of cancer patients.
Ziyi Zhao   +3 more
semanticscholar   +1 more source

Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen

open access: yesNature Immunology, 2020
The majority of tumor-infiltrating T cells exhibit a terminally exhausted phenotype, marked by a loss of self-renewal capacity. How repetitive antigenic stimulation impairs T cell self-renewal remains poorly defined.
S. Vardhana   +12 more
semanticscholar   +1 more source

Why All the Fuss about Oxidative Phosphorylation (OXPHOS)?

open access: yesJournal of Medicinal Chemistry, 2020
Certain subtypes of cancer cells require oxidative phosphorylation (OXPHOS) to survive. Increased OXPHOS dependency is frequently a hallmark of cancer stem cells and cells resistant to chemotherapy and targeted therapies.
Yibin Xu   +3 more
semanticscholar   +1 more source

RNAase III-Type Enzyme Dicer Regulates Mitochondrial Fatty Acid Oxidative Metabolism in Cardiac Mesenchymal Stem Cells [PDF]

open access: yes, 2019
Cardiac mesenchymal stem cells (C-MSC) play a key role in maintaining normal cardiac function under physiological and pathological conditions. Glycolysis and mitochondrial oxidative phosphorylation predominately account for energy production in C-MSC ...
Jin, Yue   +5 more
core   +1 more source

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