Results 1 to 10 of about 1,150,113 (298)
Oxidative Stress Signaling in Blast TBI-Induced Tau Phosphorylation
Antioxidants, 2021 Traumatic brain injury caused by blast is associated with long-term neuropathological changes including tau phosphorylation and pathology. In this study, we aimed to determine changes in initial tau phosphorylation after exposure to a single mild blast ...
Chunyu Wang +10 more
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Bioenergetic Adaptations in Chemoresistant Ovarian Cancer Cells
Scientific Reports, 2017 Earlier investigations have revealed that tumor cells undergo metabolic reprogramming and mainly derive their cellular energy from aerobic glycolysis rather than oxidative phosphorylation even in the presence of oxygen. However, recent studies have shown
Sajad Dar +8 more
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Accurate determination of the oxidative phosphorylation affinity for ADP in isolated mitochondria.
PLoS ONE, 2011 BackgroundMitochondrial dysfunctions appear strongly implicated in a wide range of pathologies. Therefore, there is a growing need in the determination of the normal and pathological integrated response of oxidative phosphorylation to cellular ATP demand.
Gilles Gouspillou +6 more
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Oxidative Phosphorylation as a Predictive Biomarker of Oxaliplatin Response in Colorectal Cancer
BiomoleculesOxaliplatin is successfully used on advanced colorectal cancer to eradicate micro-metastasis, whereas its benefits in the early stages of colorectal cancer remains controversial since approximately 30% of patients experience unexpected relapses.
Toni Martinez-Bernabe +3 more
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Frontiers in Physiology, 2016 Hyperlipidemia is one of the major risk factors of atherosclerosis and other cardiovascular diseases. This study aimed to investigate the impact of leucine rich pentatricopeptide repeat containing protein (LRPPRC)-driven hepatic oxidative phoshorylation ...
Ping Zhou +7 more
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Oxidative Phosphorylation Impairment by DDT and DDE
Frontiers in Endocrinology, 2019 There is increasing evidence supporting the characterization of the pesticide DDT and its metabolite, DDE, as obesogens and metabolic disruptors. Elucidating the mechanism is critical to understanding whether the association of DDT and DDE with obesity ...
Sarah E. Elmore, Michele A. La Merrill
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Exploring Thermal Sensitivities and Adaptations of Oxidative Phosphorylation Pathways
Metabolites, 2022 Temperature shifts are a major challenge to animals; they drive adaptations in organisms and species, and affect all physiological functions in ectothermic organisms.
Hélène Lemieux, Pierre U. Blier
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Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease
Neurobiology of Disease, 2019 Hyper-active GSK-3β favors Tau phosphorylation during the progression of Alzheimer's disease (AD). Akt is one of the main kinases inhibiting GSK-3β and its activation occurs in response to neurotoxic stimuli including, i.e., oxidative stress.
Nidhi Sharma +9 more
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BMC Medical Genetics, 2020 Background Mitochondrial encephalomyopathy caused by bi-allelic deleterious variants in TARS2 is rare. To date, only two pedigrees were reported in the literature and the connection between the gene and disease needs further study.
Xiaojing Li +8 more
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Inhibitory effect of Curcumin on phosphorylation NFκB-p65 induced by hydrogen peroxide in Bovine Endothelial Cells [PDF]
Journal of Advanced Biomedical Sciences, 2017 Background & Objective: NFκB is a dimeric transcription factor with multiple subunits. Phosphorylation of p65 (one of NFκB subunits) by oxidative stress leads to the activation of NFκB.
Narges Sharifat +5 more
doaj +2 more sources