Results 11 to 20 of about 1,214,681 (294)
Oxidative Stress Signaling in Blast TBI-Induced Tau Phosphorylation [PDF]
Antioxidants, 2021 Traumatic brain injury caused by blast is associated with long-term neuropathological changes including tau phosphorylation and pathology. In this study, we aimed to determine changes in initial tau phosphorylation after exposure to a single mild blast ...
Chunyu Wang +10 more
doaj +2 more sources
Oxidative phosphorylation revisited [PDF]
Biotechnology and Bioengineering, 2015 ABSTRACTThe fundamentals of oxidative phosphorylation and photophosphorylation are revisited. New experimental data on the involvement of succinate and malate anions respectively in oxidative phosphorylation and photophosphorylation are presented. These new data offer a novel molecular mechanistic explanation for the energy coupling and ATP synthesis ...
Sunil, Nath, John, Villadsen
openaire +3 more sources
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid-derived suppressor cells. [PDF]
FEBS Open BioBCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Chen Y, Li H.
europepmc +2 more sources
mPTP opening differently affects electron transport chain and oxidative phosphorylation at succinate and NAD-dependent substrates oxidation in permeabilized rat hepatocytes [PDF]
The Ukrainian Biochemical Journal, 2020 Mitochondrial Ca2+ overload may trigger the opening of mitochondrial permeability transition pore (mPTP) and its prolonged activation leads to cell death. ATP synthase is considered as a possible molecular component of the pore. The aim of this study was
H. M. Mazur +3 more
doaj +1 more source
Biology, 2023 Mitochondrial oxidative phosphorylation defects underlie many neurological and neuromuscular diseases. Patients’ primary dermal fibroblasts are one of the most commonly used in vitro models to study mitochondrial pathologies. However, fibroblasts tend to
Margherita Protasoni, Jan-Willem Taanman
doaj +1 more source
Chronic myeloid leukemia stem cells display alterations in expression of genes involved in oxidative phosphorylation [PDF]
, 2012 The mitochondrial respiratory chain (MRC) consists of protein complexes I, II, III, IV and V that support oxidative phosphorylation (OXPHOS), which depends on electron transport to generate adenosine triphosphate (ATP).
Flis, Krzysztof +9 more
core +1 more source
Journal of Immunology Research, 2022 Clear cell renal cell carcinoma (ccRCC) was a common cancer type diagnosed with frequent metastases, harboring an unfavorable therapeutic response, and results in a poor prognosis.
Liang Huang +4 more
doaj +1 more source
Low level of mancozeb exposure affects ovary in mice
Ecotoxicology and Environmental Safety, 2022 Mancozeb (MCZ) is widely used as a protective fungicide. This study aimed to explore the effects of low level MCZ exposure on ovary in mice. Twenty Kunming mice were randomly divided into control and MCZ groups (10 mice each).
Jialu Bao +4 more
doaj +1 more source
Cell Reports, 2018 Summary: Transitioning from a metabolically quiescent naive B cell to an antibody-secreting plasmablast requires division-dependent cellular differentiation.
Madeline J. Price +3 more
doaj +1 more source
MicroRNA‐661 modulates redox and metabolic homeostasis in colon cancer
Molecular Oncology, 2017 Cancer cell survival and metastasis are dependent on metabolic reprogramming that is capable of increasing resistance to oxidative and energetic stress. Targeting these two processes can be crucial for cancer progression.
Marta Gómez de Cedrón +8 more
doaj +1 more source