Transcriptional and translational regulation in Arc protein network of Escherichia coli's stress response [PDF]
arXiv, 2016 Recently, there has been a lot of effort in understanding sRNA mediated regulation of gene expression and how this mode of regulation differs from transcriptional regulation.In E.coli, in the presence of oxidative stress, the synthesis of sigma^s is regulated through an interesting mechanism involving both transcriptional and sRNA-mediated ...
arxiv
On the existence of Hopf bifurcations in the sequential and distributive double phosphorylation cycle [PDF]
, 2019 Protein phosphorylation cycles are important mechanisms of the post translational modification of a protein and as such an integral part of intracellular signaling and control. We consider the sequential phosphorylation and dephosphorylation of a protein at two binding sites.
arxiv +1 more source
Oxidative phosphorylation in cancer cells
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2011 Evidence suggests that mitochondrial metabolism may play a key role in controlling cancer cells life and proliferation. Recent evidence also indicates how the altered contribution of these organelles to metabolism and the resistance of cancer mitochondria against apoptosis-associated permeabilization are closely related. The hallmarks of cancer growth,
SOLAINI, GIANCARLO +2 more
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Molecular dynamics simulations and in vitro analysis of the CRMP2 thiol switch [PDF]
arXiv, 2017 Collapsin response mediator protein CRMP2 (gene: DPYSL2) is crucial for neuronal development. The homotetrameric CRMP2 complex is regulated via two mechanisms, first by phosphorylation at, and second by reduction and oxidation of the Cys504 residues of two adjacent subunits.
arxiv
Warburg Effect due to Exposure to Different Types of Radiation [PDF]
arXiv, 2013 Cancer cells maintain a high level of aerobic glycolysis (the Warburg effect), which is associated with their rapid proliferation. Many studies have reported that the suppression of glycolysis and activation of oxidative phosphorylation can repress the growth of cancer cells through regulation of key regulators.
arxiv
Single-molecule studies of the dynamics and interactions of bacterial OXPHOS complexes [PDF]
arXiv, 2015 Although significant insight has been gained into biochemical, genetic and structural features of oxidative phosphorylation (OXPHOS) at the single-enzyme level, relatively little was known of how the component complexes function together in time and space until recently.
arxiv
N-site phosphorylation systems with 2N-1 steady states [PDF]
arXiv, 2013 Multisite protein phosphorylation plays a prominent role in intracellular processes like signal transduction, cell-cycle control and nuclear signal integration. Many proteins are phosphorylated in a sequential and distributive way at more than one phosphorylation site.
arxiv
Selective advantage of aerobic glycolysis over oxidative phosphorylation [PDF]
arXivThe utilization of glycolysis in aerobic conditions have been a subject of debate for more than a century. A hypothesis supported by previous data is that glycolysis has a higher rate of ATP production per protein mass and per occupied volume than oxidative phosphorylation (OxPhos).
arxiv
Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinoma [PDF]
arXiv, 2017 Abnormal metabolism is an emerging hallmark of cancer. Cancer cells utilize both aerobic glycolysis and oxidative phosphorylation (OXPHOS) for energy production and biomass synthesis. Understanding the metabolic reprogramming in cancer can help design therapies to target metabolism and thereby to improve prognosis.
arxiv
Oxidative phosphorylation by subcellular particles from yeast [PDF]
, 1958 M.F. Utter, D.B. Keech, Peter M Nossal
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