Oxidative Stress Signaling in Blast TBI-Induced Tau Phosphorylation
Antioxidants, 2021 Traumatic brain injury caused by blast is associated with long-term neuropathological changes including tau phosphorylation and pathology. In this study, we aimed to determine changes in initial tau phosphorylation after exposure to a single mild blast ...
Chunyu Wang +10 more
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Correlation of structure and function in the oxidative phosphorylation system of submitochondrial particles [PDF]
, 1969 1. After the centrifugation of sonicated heavy beef heart mitochondria at 75, 000 × g for 10 minutes, the supernatant was centrifuged at 144, 000 × g for 30 minutes. The residue was revealed being composed of vesicular inner membrane fragments (
Goto, Nobuyuki +3 more
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Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?
Journal of Aging Research, 2012 Oxidative phosphorylation is an indispensable resource of ATP in tissues with high requirement of energy. If the ATP demand is not met, studies suggest that this will lead to senescence and cell death in the affected tissue.
Claus Desler +5 more
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Cancer Stem Cells in Small Cell Lung Cancer Cell Line H446: Higher Dependency on Oxidative Phosphorylation and Mitochondrial Substrate-Level Phosphorylation than Non-Stem Cancer Cells. [PDF]
PLoS ONE, 2016 Recently, targeting cancer stem cells (CSCs) metabolism is becoming a promising therapeutic approach to improve cancer treatment outcomes. However, knowledge of the metabolic state of CSCs in small cell lung cancer is still lacking.
Cuicui Gao +4 more
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The Interplay among PINK1/PARKIN/Dj-1 Network during Mitochondrial Quality Control in Cancer Biology: Protein Interaction Analysis [PDF]
, 2018 PARKIN (E3 ubiquitin ligase PARK2), PINK1 (PTEN induced kinase 1) and DJ-1 (PARK7) are proteins involved in autosomal recessive parkinsonism, and carcinogenic processes.
Lucas, Millikin, Narendra, Santel, Zhang
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Bioenergetic Adaptations in Chemoresistant Ovarian Cancer Cells
Scientific Reports, 2017 Earlier investigations have revealed that tumor cells undergo metabolic reprogramming and mainly derive their cellular energy from aerobic glycolysis rather than oxidative phosphorylation even in the presence of oxygen. However, recent studies have shown
Sajad Dar +8 more
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Accurate determination of the oxidative phosphorylation affinity for ADP in isolated mitochondria.
PLoS ONE, 2011 BackgroundMitochondrial dysfunctions appear strongly implicated in a wide range of pathologies. Therefore, there is a growing need in the determination of the normal and pathological integrated response of oxidative phosphorylation to cellular ATP demand.
Gilles Gouspillou +6 more
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Analytical Cellular PathologyGlioma is a devastating type of brain tumor with high morbidity and mortality rates. Despite current treatment options, the prognosis for glioma patients remains poor.
Hanwen Lu +6 more
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Redox Biology, 2020 The mitochondrial electron transport chain utilizes a series of electron transfer reactions to generate cellular ATP through oxidative phosphorylation.
Deirdre Nolfi-Donegan +2 more
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Frontiers in Cardiovascular Medicine, 2023 BackgroundMitochondrial intermediate peptidase, encoded by the MIPEP gene, is involved in the processing of precursor mitochondrial proteins related to oxidative phosphorylation.
Ling Wang +10 more
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