Results 51 to 60 of about 1,578,374 (306)
Autophagy: A cyto-protective mechanism which prevents primary human hepatocyte apoptosis during oxidative stress [PDF]
, 2012 The role of autophagy in the response of human hepatocytes to oxidative stress remains unknown. Understanding this process may have important implications for the understanding of basic liver epithelial cell biology and the responses of hepatocytes ...
Biederbick A +7 more
core +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Fine Aerosol Toxicity in Urban Environments of the Eastern Mediterranean
ProceedingsIn October 2022, the European Commission published a proposal for a revision of the Ambient Air Quality Directive, introducing stricter thresholds for pollution, more closely aligned with new limits set by the WHO, and strengthening rules for air quality
Despina Paraskevopoulou +5 more
doaj +1 more source
Oxidative stress mechanisms as potential therapeutic targets in chronic kidney disease
Studia Medyczne, 2022 Chronic kidney disease (CKD) is a gradual loss of kidney function over time, leading to the development of kidney failure. CKD is a consequence of common civilization diseases, such as arterial hypertension and diabetes, as well as primary kidney and ...
Łukasz Dobrek
doaj +1 more source
MutY-Homolog (MYH) inhibition reduces pancreatic cancer cell growth and increases chemosensitivity [PDF]
, 2016 Patients with pancreatic ductal adenocarcinoma (PC) have a poor prognosis due to metastases and chemoresistance. PC is characterized by extensive fibrosis, which creates a hypoxic microenvironment, and leads to increased chemoresistance and intracellular
Biankin, Andrew +8 more
core +1 more source
Potentiation of an antimalarial oxidant drug [PDF]
Antimicrobial Agents and Chemotherapy, 1997 In a previous report we described the synergistic antimalarial interaction between two structurally similar compounds, rufigallol and exifone. To explain this phenomenon, we proposed that exifone is transformed inside the parasitized erythrocyte into a xanthone with potent antimalarial properties.
R W, Winter +6 more
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Anti bacterial Effectiveness of Electro-Chemically Activated (ECA) Water as a Root Canal Irrigant- An In-vitro Comparative Study [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Sodium hypochlorite, is the irrigant of choice for many clinicians, but its strong toxic and damaging effects on vital periapical tissues is always a matter of concern. So, the search for a root canal irrigant with a broad antimicrobial
S. Lata +5 more
doaj +1 more source
Antioxidants, 2023 The naked mole-rat of the family Bathyergidae has been the showpiece for ageing research as they contradict the traditional understanding of the oxidative stress theory of ageing.
Paul. J. Jacobs +4 more
doaj +1 more source
Neuronal oxidative injury in the development of the epileptic disease : a potential target for novel therapeutic approaches [PDF]
, 2011 Epileptic diseases affect about 50 million people in the world and approximately 30% of patients diagnosed with epilepsy are unresponsive to current medications.
Maio, Roberto di
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