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Oxidative Stress

Annual Review of Biochemistry, 2017
Oxidative stress is two sided: Whereas excessive oxidant challenge causes damage to biomolecules, maintenance of a physiological level of oxidant challenge, termed oxidative eustress, is essential for governing life processes through redox signaling.
Helmut, Sies   +2 more
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Postprandial Oxidative Stress

Biological Chemistry, 2002
Consumption of a meal containing oxidized and oxidizable lipids gives rise to an increased plasma concentration of lipid hydroperoxides, detectable by a sensitive chemiluminescence procedure. This is associated with increased susceptibility of LDL to oxidation, apparently due a structural perturbation at the particle surface brought about by lipid ...
URSINI, FULVIO, A. SEVANIAN
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Cutaneous oxidative stress

Journal of Cosmetic Dermatology, 2012
SummaryThe earliest known microfossil records suggest that microorganisms existed on the earth approximately 3.8 billion years ago. Not only did sunlight drive this evolutionary process, but it also allowed photosynthetic organisms to elaborate oxygen and fundamentally change the earth’s atmosphere and subsequent evolution.
Thomas G, Polefka   +3 more
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Demystifying Oxidative Stress

2020
The hypothesis that reactive oxygen species (ROS) can be not just associated with but causally implicated in disease was first made in 1956, but so far, the oxidative stress theory of disease has not led to major therapeutic breakthrough, and the use of antioxidant is now confined to the field of complementary medicine. This chapter reviews the lack of
Ghezzi, Pietro, Mooradian, Arshag D
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Oxidative Stress

Veterinary Clinics of North America: Equine Practice, 2007
Oxidative stress refers to the cellular injury and pathologic change that occurs when there is an imbalance favoring oxidants over antioxidants within a living organism. In human medicine, oxidative stress has been implicated in numerous disease processes, which has led to further research into the clinical benefits and efficacy of antioxidant therapy.
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Oxidative Stress

EcoSal Plus, 2009
The ancestors of Escherichia coli and Salmonella ultimately evolved to thrive in air-saturated liquids, in which oxygen levels reach 210 μM at 37°C. However, in 1976 Brown and colleagues reported that some sensitivity persists: growth defects still become apparent when hyperoxia is imposed on
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Oxidative Stress and Uremia

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
FLOCCARI F   +8 more
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Redefining Oxidative Stress

Antioxidants & Redox Signaling, 2006
Oxidative stress is often defined as an imbalance of pro-oxidants and antioxidants, which can be quantified in humans as the redox state of plasma GSH/GSSG. Plasma GSH redox in humans becomes oxidized with age, in response to oxidative stress (chemotherapy, smoking), and in common diseases (type 2 diabetes, cardiovascular disease).
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Oxidant signals and oxidative stress

Current Opinion in Cell Biology, 2003
Although oxidants clearly possess the capacity to behave in a random and destructive fashion, growing evidence suggests that in many instances the production of reactive oxygen species is tightly regulated and their downstream targets exquisitely specific.
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