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Oxidative Stress

Veterinary Clinics of North America: Equine Practice, 2007
Oxidative stress refers to the cellular injury and pathologic change that occurs when there is an imbalance favoring oxidants over antioxidants within a living organism. In human medicine, oxidative stress has been implicated in numerous disease processes, which has led to further research into the clinical benefits and efficacy of antioxidant therapy.
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Oxidative Stress

EcoSal Plus, 2009
The ancestors of Escherichia coli and Salmonella ultimately evolved to thrive in air-saturated liquids, in which oxygen levels reach 210 μM at 37°C. However, in 1976 Brown and colleagues reported that some sensitivity persists: growth defects still become apparent when hyperoxia is imposed on
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Oxidative stress in uremia

Current Opinion in Nephrology and Hypertension, 2003
Oxidative stress has been described as 'a disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. In uremic patients, an increase in oxidative stress may occur because of the loss of residual renal function, and may be exacerbated by dialysis.
Jonathan, Himmelfarb, Raymond M, Hakim
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Oxidative Stress and Osteoporosis

Journal of Bone and Joint Surgery, 2021
➤ Oxidative stress has been implicated as a causative factor in many disease states, possibly including the diminished bone mineral density in osteoporosis.➤ Understanding the effects of oxidative stress on the development of osteoporosis may lead to further research improving preventative and therapeutic measures that can ...
Jeff S. Kimball   +2 more
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Nedd8 and Oxidative Stress

2021
All living organisms are exposed to oxidative stress produced by reactive oxygen species (ROS) (McCord, 2000; Pajares et al., 2015). ROS, which are highly unstable and reactive, play an important role in various cellular reactions and signals. The protein post-translation modifications (PTM) induced by ROS trigger progressive cell and tissue damage ...
Pick E, Serino G
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Oxidant signals and oxidative stress

Current Opinion in Cell Biology, 2003
Although oxidants clearly possess the capacity to behave in a random and destructive fashion, growing evidence suggests that in many instances the production of reactive oxygen species is tightly regulated and their downstream targets exquisitely specific.
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Cutaneous oxidative stress

Journal of Cosmetic Dermatology, 2012
SummaryThe earliest known microfossil records suggest that microorganisms existed on the earth approximately 3.8 billion years ago. Not only did sunlight drive this evolutionary process, but it also allowed photosynthetic organisms to elaborate oxygen and fundamentally change the earth’s atmosphere and subsequent evolution.
Thomas G, Polefka   +3 more
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Oxidative stress in epilepsy

Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2019
This article contains an analysis of clinical and experimental studies in which oxidative stress is considered as a possible mechanism in the pathogenesis of epilepsy. Oxidative stress occurs as a result of brain damage after epileptic seizures and may later cause epileptogenesis. Patients with epilepsy showed a high level of lipid peroxidation markers,
A I, Fedin, E V, Starykh, D V, Torshin
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Oxidant stress and atherosclerosis

Current Opinion in Pharmacology, 2004
Overproduction of reactive oxygen species or increased oxidative stress is considered a major mechanism involved in the pathogenesis of endothelial dysfunction, the initiation and progression of atherosclerosis and its adverse events. Evidence supports the importance of nitric oxide derived from endothelial nitric oxide synthase as a vasoprotective ...
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Oxidative stress in the placenta

Histochemistry and Cell Biology, 2004
Pregnancy is a state of oxidative stress arising from increased placental mitochondrial activity and production of reactive oxygen species (ROS), mainly superoxide anion. The placenta also produces other ROS including nitric oxide, carbon monoxide, and peroxynitrite which have pronounced effects on placental function including trophoblast proliferation
Leslie, Myatt, Xiaolan, Cui
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