Results 281 to 290 of about 516,802 (337)

Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration

open access: yesCell Proliferation, EarlyView.
Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen   +9 more
wiley   +1 more source

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

open access: yesCell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang   +4 more
wiley   +1 more source

Effectiveness of dietary interventions in individuals with diabetes for preventing and healing chronic wounds; a systematic review with meta‐analysis

open access: yesDiabetic Medicine, EarlyView.
Abstract Background Optimising the nutritional status of individuals with diabetes is essential to optimise glycaemic control, as well as to prevent and promote wound healing. A variety of nutrition interventions are available. This systematic review and meta‐analysis aimed to describe and synthesise the effectiveness of nutrition interventions for the
Hailey R. Donnelly   +6 more
wiley   +1 more source

Why, how and in whom should we measure levels of lipoprotein(a): A review of the latest evidence and clinical implications

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Lipoprotein(a) [Lp(a)] is a genetically determined, causal risk factor for atherosclerotic cardiovascular disease (ASCVD) and calcific aortic valve disease (CAVD). Despite robust evidence from epidemiological and genetic studies, Lp(a) remains underrecognised in clinical practice due to challenges in measurement, lack of guideline familiarity ...
Alexander C. Razavi   +4 more
wiley   +1 more source

Predictors of diabetic ketoacidosis in patients with insulin‐deficient diabetes phenotype initiating SGLT2 inhibitors

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To identify predictors of diabetic ketoacidosis (DKA) in patients with an insulin‐deficient phenotype initiating sodium‐glucose cotransporter 2 inhibitor (SGLT2i) therapy. Materials and Methods This retrospective cohort study analysed data from 31 900 patients with diabetes aged 18–70 identified as having an insulin‐deficient phenotype ...
Anat Tsur   +4 more
wiley   +1 more source

Association of device measured physical activity with liver fat and stiffness in people with type 1 diabetes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims This study aimed to investigate the association between physical activity (PA) metrics and liver fat and stiffness in people with type 1 diabetes (T1D). Materials and Methods People with T1D attending clinics or participating in ongoing research at the Dasman Diabetes Institute in Kuwait were invited to participate. Liver fat fraction and
Ebaa Al Ozairi   +7 more
wiley   +1 more source

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