Results 121 to 130 of about 44,293 (292)
Transcriptional Regulation of Microglial Metabolic and Activation States by P2RY12
Glia, EarlyView.Transcriptionally, P2RY12‐deficient microglia show heightened metabolic activity, iron handling, and oxidative stress at baseline. Upon LPS challenge, impaired glutathione antioxidant responses suggest increased vulnerability to ferroptosis. ABSTRACT Microglia are the resident immune cells of the CNS.
Aida Oryza Lopez‐Ortiz +9 more
wiley +1 more source
University proceedings. Volga region. Natural sciences
Известия высших учебных заведений. Поволжский регион: Естественные наукиBackground. For scientifically substantiated and effective application of new biocidal compounds as means of protecting industrial materials from biodamage, ecophysiological studies are necessary to assess their effect on destructor microorganisms.
A.Yu. Shishkin +4 more
doaj +1 more source
Beitrag zur Charakterisierung des Oxidoreductase-Inhibitors [PDF]
, 1976 H. Gallati
openalex +1 more source
Reversible Conjugate Addition in Thiol‐Mediated Uptake
Helvetica Chimica Acta, EarlyView.In a firework of dynamic covalent Michael addition chemistry, unorthodox, sulfur−rich bissulf(ox)idoenone acceptors activate classical reversible cyanoacrylamide acceptors to record performances in thiol−mediated uptake and reveal two new, mechanistically distinct and selective dynamic covalent exchange cascades with cellular thiols to activate and ...
Yuheng Zhang +7 more
wiley +1 more source
Three forms of xanthine: acceptor oxidoreductase in rat heart. [PDF]
, 1986 Zbigniew Kamiński +3 more
openalex +1 more source
International Journal of Cancer, EarlyView.Abstract Hepatocellular carcinoma (HCC) represents the predominant form of primary liver cancer and is frequently identified at a late stage, necessitating systemic therapy. However, resistance to first‐line tyrosine kinase inhibitor therapies, such as sorafenib and lenvatinib, remains a significant clinical challenge.
Longtao Zhao +6 more
wiley +1 more source
Xanthine oxidoreductase is present in human synovium. [PDF]
, 1987 R E Allen +3 more
openalex +1 more source
TBCancer: A database for exploring characteristics and functions of tissue‐biased genes in cancer
iMetaOmics, EarlyView.This study defined 10,921 tissue‐biased genes across 54 normal tissues and 41 cancer types. Tumor‐associated tissue‐biased genes exhibit downregulation, mutations, and epigenetic modifications, correlating with poor clinical outcomes. Their inactivation promotes tumorigenesis by enhancing stemness and immune evasion, highlighting their value as ...
Zhuobin Lin +7 more
wiley +1 more source