Results 171 to 180 of about 43,837 (307)
Corrigendum: Exploring proinsulin proteostasis: insights into beta cell health and diabetes. [PDF]
Zavarzadeh PG+7 more
europepmc +1 more source
NQO1‐Responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell‐Targeted Migrastatic
The design, synthesis, biochemical, and cell biological evaluation of the NQO1‐targeted prodrug BQTML‐CB is reported. BQTML‐CB selectively releases cytochalasin B upon activation by the quinone‐oxidoreductase NQO1 associated with invasiveness of cancer cells, representing a novel approach to improve cancer selectivity and reduce immunosuppressive ...
Mervic D. Kagho+10 more
wiley +1 more source
Aryl-alcohol oxidases: catalysis, diversity, structure-function and emerging biotechnological applications. [PDF]
Cinca-Fernando P+3 more
europepmc +1 more source
It is demonstrated that a combination of mechanochemistry and accelerated aging can be used to synthesize Hydrogen‐bonded Organic Framework (HOF) biocomposites. The vapor‐induced growth enhances enzyme loading, ensures a more homogeneous enzyme distribution, and improves protective properties due to distinct growth mechanisms and kinetics.
Michael R. Hafner+8 more
wiley +1 more source
A Quinoxaline 1,4-Dioxide Activates DNA Repair Systems in <i>Mycobacterium smegmatis</i>: A Transcriptomic Study. [PDF]
Bekker OB+13 more
europepmc +1 more source
A high‐glucose environment induced an imbalance in mitochondrial homeostasis, which resulted in the inhibition of bone tissue regeneration. In this study, we first introduce the exogenous noninvasive direct current electric field (DCEF) strategy for regulating mitochondrial homeostasis and explore its effect on bone regeneration in high‐glucose ...
Dongzong Huang+14 more
wiley +1 more source
MHNfs: Prompting In-Context Bioactivity Predictions for Low-Data Drug Discovery. [PDF]
Schimunek J, Luukkonen S, Klambauer G.
europepmc +1 more source
Involvement of a single thiol group in the conversion of the NAD+-dependent activity of rat liver xanthine oxidoreductase to the O2-dependent activity [PDF]
Zbigniew Kamiński, Maria Jeżewska
openalex +1 more source