Results 201 to 210 of about 43,837 (307)

Interplay of niche and respiratory network in shaping bacterial colonization. [PDF]

J Biol Chem
Srivastav S, Biswas A, Anand A.
europepmc   +1 more source

ACSM5 Regulates Ferroptosis in Hepatocellular Carcinoma by Up‐Regulating POR and Modulating Lipid Metabolism

Cancer Science, EarlyView.
ACSM5 induced ferroptosis in HCC by up‐regulating cytochrome P450 oxidoreductase (POR). The metabolic transformation of linoleic acid to arachidonic acid was also promoted by ACSM5; thereby, the sensitivity to ferroptosis was elevated. ABSTRACT The medium‐chain fatty acyl‐CoA synthetase‐5 (ACSM5) plays a crucial role in the development of some cancers.
Zhengqiang Wu, Xiaofeng Xiong, Mingyi Dong, Linfei Luo, Zixiang Huang, Kedong Xu, Lianwu Zhao, Fenfen Wang, Zhili Wen   +8 more
wiley   +1 more source

Activity of NAD(P)H-Oxidoreductases in Ovarian Cancer. [PDF]

Biomedicines
Fedorova MV, Voznesensky VI, Sosnova EA, Proskurnina EV.   +3 more
europepmc   +1 more source

Dopaminergic neurotoxins, MPTP and MPP+, inhibit activity of mitochondrial NADH-ubiquinone oxidoreductase.

, 1986
Yoshikuni Mizuno, Nobuhito Sone, Tomohiko Saitoh   +2 more
openalex   +2 more sources

Tryptophan Suppresses FTH1‐Driven Ferritinophagy, a Key Correlate of Prognosis in Hepatocellular Carcinoma

Cell Proliferation, EarlyView.
Intracellular tryptophan levels modulate selective autophagy of FTH1 via the NCOA4 pathway. This autophagic process then inhibits 6‐HMT synthesis, which then results in an increase in reactive oxygen species and ferroptosis. ABSTRACT Hepatocellular carcinoma (HCC) remains a lethal malignancy with limited therapeutic options.
Xinxiang Cheng, Xin Ge, Chi Zhang, Xingye Yang, Zhengxin Yu, Min Zhang, Wen Cao, Qingtao Ni, Yang Liu, Songbing He, Yin Yuan   +10 more
wiley   +1 more source

Gene expression analysis for stem browning in the mushroom Lentinula edodes. [PDF]

Mycoscience
Zhang J, Tanaka Y, Ono A, Sato T, Suzuki T, Akimoto S, Tanaka Y, Iwami S, Iwamoto A, Tanaka N, Konno N, Suzuki T.   +11 more
europepmc   +1 more source

Type 1 Diabetes: A Guide to Autoimmune Mechanisms for Clinicians

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Type 1 diabetes (T1D) results from the destruction of pancreatic beta cells by autoreactive T lymphocytes, leading to insulin deficiency and lifelong insulin dependence. It develops in genetically predisposed individuals, triggered by environmental or immunological factors.
François‐Xavier Mauvais, Peter M. van Endert   +1 more
wiley   +1 more source

Discovery and characterization of an FAD-dependent glucose 6-dehydrogenase. [PDF]

J Biol Chem
Fujii T, Honda M, Fujii W, Shimada Y, Takeuchi M, Ogawa J.   +5 more
europepmc   +1 more source

Genomic context analysis enables the discovery of an unusual NAD‐dependent racemase in phosphonate catabolism

The FEBS Journal, EarlyView.
The authors identify PbfF (previously annotated as a NAD‐dependent dehydrogenase) as a hitherto unknown enzyme in phosphonate catabolism. Guided by genome context analysis, they show that PbfF is actually a racemase, serving to degrade the natural compound (S)‐2‐amino‐1‐hydroxyethylphosphonate (S‐HAEP).
Francesca Ruffolo, Silvia Conciatori, Giovanni Merici, Tamara Dinhof, Jason P. Chin, Claudio Rivetti, Andrea Secchi, Katharina Pallitsch, Alessio Peracchi   +8 more
wiley   +1 more source

Gluconobacter oxydans DSM 50049 - an efficient biocatalyst for oxidation of 5-formyl-2-furancarboxylic acid (FFCA) to 2,5-furandicarboxylic acid (FDCA). [PDF]

Microb Cell Fact
Sayed M, Ismail M, Sivasubramanian A, Kawano R, Li C, Glaser SJ, Hatti-Kaul R.   +6 more
europepmc   +1 more source