Results 221 to 230 of about 54,875 (301)

Fungal Degradation of Microplastics-An Environmental Need. [PDF]

Toxics
West RR, MacDonald MT, Emenike CU.
europepmc   +1 more source

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

The FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna, Alessandro Cherubini, Ersilia Varone, Serena Germani, Alice Marrazza, Ester Zito   +5 more
wiley   +1 more source

Energetics and Ecological Implications of Bacterial Electron Transport Chains. [PDF]

Environ Microbiol Rep
Xie N, Brown AM, Wang X.
europepmc   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, EarlyView.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source

Biofuel Cells Based on Oxidoreductases and Electroactive Nanomaterials: Development and Characterization. [PDF]

Biosensors (Basel)
Demkiv O, Stasyuk N, Gayda G, Zakalska O, Gonchar M, Nisnevitch M.   +5 more
europepmc   +1 more source

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

The FEBS Journal, EarlyView.
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero, Juan Luis Pacheco‐Garcia, Pavla Vankova, Dmitry Loginov, Isabel Quereda‐Moraleda, Jose Manuel Martin‐Garcia, Petr Man, Angel Luis Pey, Milagros Medina   +8 more
wiley   +1 more source

Cell surface thiol-disulfide regulation in cancer: Mechanisms, implications, and theranostic strategies. [PDF]

Redox Biol
Lühle J, Seeberger PH, Moscovitz O.
europepmc   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

The FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney, James Griffin, Nouf Khan, Balnur Ibrash, Matthew J. O'Connor, Tomas Venit, Elizabeth Mayela Ambrosio, Spiros A. Pergantis, Elke Ober, Piergiorgio Percipalle, Kirsten C. Sadler   +10 more
wiley   +1 more source

Transcriptomic and proteomic insights into feather keratin degradation by <i>Fervidobacterium</i>. [PDF]

Front Microbiol
Javier-López R, Kielbasa M, Armengaud J, Birkeland NK.   +3 more
europepmc   +1 more source

Drivers of strigolactone diversity: P450s in strigolactone biosynthesis

Journal of Integrative Plant Biology, EarlyView.
This review summarizes the discovery and functional identification of cytochrome P450 in strigolactone biosynthesis, classifies and summarizes the members discovered so far, clarifies their biological significance, discusses the technology of strigolactone synthesis research, and finally describes some problems in strigolactone research and potential ...
Changbin Niu, Harro J. Bouwmeester, Changsheng Li   +2 more
wiley   +1 more source