Results 1 to 10 of about 3,919 (182)
Molecules, 2011 Two new heteroyohimbine-type oxindole alkaloids, rauniticine-allo-oxindole B and rauniticinic-allo acid B, have been successfully isolated from the stems extract of Malaysian Uncaria longiflora var. pteropoda. The structures of the two new alkaloids were
Khalijah Awang +2 more
exaly +3 more sources
Azobenzene-Oxindole Photochromic Dyads. [PDF]
Angew Chem Int Ed EnglAbstract Manipulation of molecular geometry using photoresponsive units is a powerful tool in supramolecular chemistry, smart materials, and photopharmacology. Current synthetic chemistry offers many responsive molecules that perform such a task.
Ovalle M, Doellerer D, Feringa BL.
europepmc +4 more sources
Preparation of spirocyclic oxindoles by cyclisation of an oxime to a nitrone and dipolar cycloaddition [PDF]
Beilstein Journal of Organic ChemistryOxindoles are an important class of compounds with significant biological activities. Spirocyclic derivatives are present in a variety of natural products.
Beth L. Ritchie +2 more
doaj +2 more sources
Solvent controlled synthesis of spiro and nonspiro indolinones with aminonaphthoquinone and pyrazolone moieties [PDF]
Scientific ReportsThis study describes the design and synthesis of novel hybrid molecular architectures based on the privileged indolin-2-one (oxindole) scaffold. The research leverages a multi-component reaction strategy, employing isatins, 2-amino-1,4-naphthoquinone ...
Hamed Pezhman +3 more
doaj +2 more sources
Results in Chemistry, 2023 Oxindole derivatives have been known to possess anticancer, antimicrobial, antiviral, antioxidative, and other pharmacological activities. A substantial group of oxindole compounds are studied as anticancer and antimicrobial agents.
Esra Köse +2 more
doaj +1 more source
Antioxidants, 2020 Recent studies demonstrate that 5-fluoro-2-oxindole inhibits neuropathic pain but the antinociceptive actions of this drug and its effects on the plasticity, oxidative and inflammatory changes induced by peripheral inflammation as well as on the effects ...
Alejandro Redondo +2 more
doaj +1 more source
Molecules, 2021 A synthetic route for the enantioselective construction of the tetracyclic spiro[indolizidine-1,3′-oxindole] framework present in a large number of oxindole alkaloids, with a cis H-3/H-15 stereochemistry, a functionalized two-carbon substituent at C-15 ...
Nihan Yayik +4 more
doaj +1 more source
Base-free enantioselective SN2 alkylation of 2-oxindoles via bifunctional phase-transfer catalysis
Beilstein Journal of Organic Chemistry, 2021 N-Protected oxindole derivatives of unprecedented malleability bearing ester moieties at C-3 have been shown to participate in enantioselective phase-transfer-catalysed alkylations promoted by ad-hoc designed quaternary ammonium salts derived from ...
Mili Litvajova +3 more
doaj +1 more source
Catalytic Enantioselective Fluorination of Oxindoles. [PDF]
ChemInform, 2005 AbstractFor Abstract see ChemInform Abstract in Full Text.
Yoshitaka, Hamashima +4 more
openaire +2 more sources
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 The serine/threonine protein kinases CDK2 and GSK-3β are key oncotargets in breast cancer cell lines, therefore, in the present study three series of oxindole-benzofuran hybrids were designed and synthesised as dual CDK2/GSK-3β inhibitors targeting ...
Wagdy M. Eldehna +5 more
doaj +1 more source