Results 51 to 60 of about 2,990 (181)

New‐Era Polymer Thermoelectrics: Material Innovations, Doping Frontiers, Decoupling Strategies, and Unconventional Applications

open access: yesAdvanced Materials, Volume 38, Issue 43, 3 August 2026.
The field of polymer thermoelectrics is entering a new era, featuring breakthroughs in addressing the conventional performance disparity between p‐type and n‐type polymers, pioneering doping frontiers, and sophisticated decoupling strategies. This review explores innovations in molecular design and superior stabilities, bridging the gap from ...
Suhao Wang
wiley   +1 more source

Alkenyl oxindole is a novel PROTAC moiety that recruits the CRL4DCAF11 E3 ubiquitin ligase complex for targeted protein degradation.

open access: yesPLoS Biology
Alkenyl oxindoles have been characterized as autophagosome-tethering compounds (ATTECs), which can target mutant huntingtin protein (mHTT) for lysosomal degradation. In order to expand the application of alkenyl oxindoles for targeted protein degradation,
Ying Wang   +14 more
doaj   +1 more source

Azobenzene‐Oxindole Photochromic Dyads

open access: yesAngewandte Chemie
Abstract Manipulation of molecular geometry using photoresponsive units is a powerful tool in supramolecular chemistry, smart materials, and photopharmacology. Current synthetic chemistry offers many responsive molecules that perform such a task.
Ovalle, Marco   +2 more
openaire   +3 more sources

Barbituric Acids as Nucleophiles in Enantioselective Mannich Reactions: Organocatalytic Access to Quaternary Aminopyrazolone–Barbiturate Adducts

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
An enantioselective Mannich reaction using barbituric acids as nucleophiles provides access to chiral heterocycles bearing quaternary stereocenters. The transformation is catalyzed by a bifunctional thiourea with high selectivity. An immobilized catalyst enables recycling and application under continuous‐flow conditions, offering an efficient and ...
Rodrigo Sánchez‐Molpeceres   +4 more
wiley   +1 more source

SYNTHESIS AND ANTIVIRAL ACTIVITY OF NEW THIAZOLE, 1,2,4-TRIAZOL AND OXINDOLE DERIVATIVES [PDF]

open access: yesChemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2011
The synthesis and antiviral activity evaluation of new derivatives of 2-aminothiazole, 1,2,4-triazole, as well as oxindoles has been realized. The synthesized compounds exhibited different cytotoxicity, in particular, oxindols 4 , 5 , 7 , 8 , 9, 10, 11,
Oleg Radul   +5 more
doaj  

Mechanochemistry as an Emerging Tool for Organofluorine Chemistry

open access: yesChemistry–Methods, Volume 6, Issue 8, August 2026.
Fluorinated scaffolds are central across many areas of chemistry, driving the demand for efficient and sustainable synthetic methods. Mechanochemistry has emerged as a powerful alternative to conventional approaches, offering reduced environmental impact, shorter reaction times, and unique reactivity and selectivity.
Marie Caldiero   +3 more
wiley   +1 more source

Auf dem Weg zu chromoselektiven Transformationen in biologischen Systemen: Perspektiven und Herausforderungen

open access: yesAngewandte Chemie, Volume 138, Issue 31, 27 July 2026.
Die Kontrolle biologischer Systeme mit organischen Chromophoren hat sich zu einer vielversprechenden Strategie entwickelt und findet Anwendung von der chemischen Biologie bis hin zur Medizin. Die Komplexität von In‐vivo‐Systemen lässt sich jedoch nicht mit nur einer einzigen Lichtwellenlänge adäquat abbilden.
Nadja A. Simeth
wiley   +1 more source

Toward Chromoselective Transformations in Biological Systems: Perspectives and Challenges

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 31, 27 July 2026.
Controlling biological systems with small‐molecule chromophores has evolved into a powerful strategy and is applied from chemical biology to medicine. However, the complexity of in vivo systems cannot be matched by a single wavelength of light. Developing methods to combine and individually control multiple chromophores is crucial.
Nadja A. Simeth
wiley   +1 more source

Ag/Pyridine Co-Mediated Oxidative Arylthiocyanation of Activated Alkenes

open access: yesMolecules, 2018
An efficient Ag/pyridine co-mediated oxidative arylthiocyanation of activated alkenes via radical addition/cyclization cascade process was developed.
De-Long Kong   +5 more
doaj   +1 more source

Synthesis of chiral 3-substituted 3-amino-2-oxindoles through enantioselective catalytic nucleophilic additions to isatin imines

open access: yesBeilstein Journal of Organic Chemistry, 2018
This review collects the recent developments in the synthesis of chiral 3-substituted 3-amino-2-oxindoles based on enantioselective catalytic nucleophilic additions to isatin imines published since the beginning of 2015.
Hélène Pellissier
doaj   +1 more source

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