Results 251 to 260 of about 60,467 (293)

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Hypoxia tolerance of intertidal triplefin fish is associated with low critical oxygen tension and high phosphorylating capacity in brain mitochondria. [PDF]

Sci Rep
Devaux JBL, McArley TJ, Herbert N, Hickey AJR.   +3 more
europepmc   +1 more source

Physiological mechanisms underlying enhanced performance with blood flow restriction training: neuromuscular, vascular and metabolic adaptations

The Journal of Physiology, EarlyView.
Abstract figure legend We investigated how 6 weeks of dynamic knee‐extensor interval training with blood flow restriction (BFR‐leg) and without (CTRL‐leg) impacts performance and its mechanisms using non‐invasive methods. Specifically, we used gold‐standard methods to assess neuromuscular function, vascular function using Doppler ultrasound, and near ...
Colin Lavigne, Valentin Mons, Clément Lemineur, Oliver Meste, Georges Lefthériotis, Grégory M. Blain   +5 more
wiley   +1 more source

Multi-omics identification and validation of oxidative phosphorylation-related hub genes in schizophrenia. [PDF]

Front Genet
Zhou Y, Zhang S, Liu YX, Dai X, Zhang T, Xu XT, Deng SN, Yang MY, Fan Z.   +8 more
europepmc   +1 more source

Mitochondrial physiology in cardiac muscle of deer mice native to high altitude

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude deer mice exhibited evolved changes in mitochondrial energy metabolism and reactive oxygen species (ROS) management that may support cardiac performance under cold hypoxic conditions. High‐altitude mice had increased activity of lactate dehydrogenase (LDH) in the heart, probably enhancing the capacity for lactate ...
Ranim Saleem, Samuel G. Robichaud, Simon G. Lamarre, Graham R. Scott   +3 more
wiley   +1 more source

Metabolic reprogramming tailors T cell immunity in sepsis. [PDF]

Front Immunol
Xian D, Chen F, Liu B, Wang L.
europepmc   +1 more source

Identification of Crucial Drug Targets and Pathways to Reprogram Drug Resistance Through Epigenetic Modulation in Advanced Lung Cancer Using Integrated Bioinformatics Approach

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman, Mossammat Rima Akter, Nur Alam   +2 more
wiley   +1 more source

The enhanced photothermal therapy against gastric cancer by mitochondria/STAT3-targeted nanoplatform with OXPHOS blocking. [PDF]

Mater Today Bio
Wang W, Wang L, Zhang G, Zheng Y, Huang Q, Zou M, Zhang Y, Wu S, Sui Y, Qiu J, Zhang Z, Fang Q, Wang X, Liang P.   +13 more
europepmc   +1 more source

Treadmill exercise alleviates Alzheimer's disease pathologies in APP/PS1 mice through modulation of microglial glucose metabolic reprogramming. [PDF]

Front Aging Neurosci
Liang F, Sun F, Guo C, Zhong H.
europepmc   +1 more source

Developmental regulation of fetal mitochondrial respiratory function towards term: the role of glucocorticoid and thyroid hormones. [PDF]

J Endocrinol
Fowden AL, Davies KL, Camm EJ, Forhead AJ, Murray AJ.   +4 more
europepmc   +1 more source