Results 71 to 80 of about 27,463 (211)

Oxygen-induced retinopathy in the mouse.

Investigative ophthalmology & visual science, 1994
PURPOSE: To develop oxygen-induced retinopathy in the mouse with reproducible and quantifiable proliferative retinal neovascularization suitable for examining pathogenesis and therapeutic intervention for retinal neovascularization in retinopathy of prematurity (ROP) and other vasculopathologies.
Smith, Lois, Wesolowski, Eva, McLellan, Angela, Kostyk, Sandra K., D'Amato, Robert, Sullivan, Richard, D'Amore, Patricia   +6 more
openaire   +2 more sources

The Performance of Selective Screening Ultrasound to Detect the Small‐for‐Gestational‐Age Foetus: A Prospective Cohort Study Nested Within the DESiGN Randomised Control Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Evidence on the performance of foetal growth ultrasound parameters to detect the Small‐for‐Gestational‐Age (SGA) foetus for a selective cohort is limited. We report the performance of estimated foetal weight under the 10th percentile (EFW < 10th) at the last selective screening ultrasound to detect SGA based on gestational age of ...
Charles Arcus, James Elhindi, Chivon Winsloe, Andrew Copas, Sophie Relph, Annette Briley, Kirstie Coxon, Mark Johnson, Asma Khalil, Deborah A. Lawlor, Christoph Lees, Neil Marlow, Louise Page, Andrew Shennan, Jane Sandall, Tanya Nippita, Matias C. Vieira, Dharmintra Pasupathy   +17 more
wiley   +1 more source

Choroidal Involution Is a Key Component of Oxygen-Induced Retinopathy

Investigative Opthalmology & Visual Science, 2011
Retinopathy of prematurity (ROP) is a major cause of visual handicap in the pediatric population. To date, this disorder is thought to stem from deficient retinal vascularization. Intriguingly, functional electrophysiological studies in patients with mild or moderate ROP and in the oxygen-induced retinopathy (OIR) model in rats reveal central ...
Shao, Zhuo, Dorfman, Allison, Seshadri, Swathi, Djavari, Mikheil, Kermorvant-Duchemin, Elsa, Sennlaub, Florian, Blais, Martine, Polosa, Anna, Varma, Daya, Joyal, Jean-Sébastien, Lachapelle, Pierre, Hardy, Pierre, Sitaras, Nicholas, Picard, Émilie, Mancini, Joseph, Sapieha, Przemyslaw, Chemtob, Sylvain   +16 more
openaire   +2 more sources

Changes in choroidal and retinal thickness 6 months before and during 18 months of orthokeratology lens treatment in myopic children

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate changes in choroidal and retinal thickness before and during myopia control treatment with orthokeratology lenses (OKL) in myopic children. Methods This was a sub‐study of CONTROL and CONTROL2 studies. The present study was a 2‐year, prospective, single‐group interventional study consisting of a 6‐month pre‐treatment ...
P. O. Hansen, F. Møller, T. M. Jakobsen
wiley   +1 more source

The oscillatory response of the electroretinogram and neuronal adaptation

Acta Ophthalmologica, EarlyView.
Abstract After more than 50 years, there still remains a challenge and an interest to know more as well as extend and deepen our understanding of the small rapid wavelets, the oscillatory potentials (OPs), of the electroretinogram (ERG) and the neuronal adaptation of the retina.
Lillemor Wachtmeister, Anders Eklund
wiley   +1 more source

Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathy

EMBO Molecular Medicine, 2020
Diabetic retinopathy (DR) is a common complication of diabetes and leads to blindness. Anti‐VEGF is a primary treatment for DR. Its therapeutic effect is limited in non‐ or poor responders despite frequent injections.
Jie‐hong Wu, Ya‐nan Li, An‐qi Chen, Can‐dong Hong, Chun‐lin Zhang, Hai‐ling Wang, Yi‐fan Zhou, Peng‐Cheng Li, Yong Wang, Ling Mao, Yuan‐peng Xia, Quan‐wei He, Hui‐juan Jin, Zhen‐yu Yue, Bo Hu   +14 more
doaj   +1 more source

The impact of coronary artery bypass grafting on the short‐ and long‐term development and progression of diabetic retinopathy: A Danish national matched cohort study

Acta Ophthalmologica, EarlyView.
Abstract Purpose Diabetic retinopathy (DR) is a frequent long‐term complication of diabetes. While hemodynamic changes are known risk factors for DR, the effect of coronary artery bypass grafting (CABG) on the development of DR is poorly investigated.
Lukas Greve Maschoreck, Lonny Stokholm, Frederik Nørregaard Pedersen, Nis Andersen, Jens Andresen, Toke Bek, Sebastian Dinesen, Javad Hajari, Steffen Heegaard, Kurt Højlund, Caroline Schmidt Laugesen, Ryo Kawasaki, Sören Möller, Katja Christina Schielke, Yousif Subhi, Anne Suhr Thykjær Petersen, Jakob Grauslund   +16 more
wiley   +1 more source

The effect of rhegmatogenous retinal detachment on retinal oxygenation

Acta Ophthalmologica, EarlyView.
Abstract Purpose Little is known about the effects of retinal detachment on oxygen extraction from retinal vessels. The role of oxygen supply from the retinal vessels in a detached area has not previously been investigated in vivo in humans. Retinal oximetry is a non‐invasive measurement of retinal oxygen saturation.
Anne‐Sofie Petri, Sindri Traustason, Sveinn H. Hardarson, Alexander Kyhnel, Einar Stefansson, Jens F. Kiilgaard, Morten la Cour, Javad Nouri Hajari, Therese Krarup   +8 more
wiley   +1 more source

Role of myeloid cells in ischemic retinopathies: recent advances and unanswered questions

Journal of Neuroinflammation
Myeloid cells including microglia and macrophages play crucial roles in retinal homeostasis by clearing cellular debris and regulating inflammation. These cells are activated in several blinding ischemic retinal diseases including diabetic retinopathy ...
Rami A. Shahror, Carol A. Morris, Aya A. Mohammed, Melissa Wild, Bushra Zaman, Christian D. Mitchell, Paul H. Phillips, Nancy J. Rusch, Esraa Shosha, Abdelrahman Y. Fouda   +9 more
doaj   +1 more source

Folic Acid Supplementation Inhibits Proliferative Retinopathy of Prematurity

Biomolecules
Background: Retinopathy of prematurity (ROP) is the major cause of blindness in children. It is a biphasic disease with retinal vessel growth cessation and loss (Phase I) followed by uncontrolled retinal vessel growth (Phase II).
Shen Nian, Yan Zeng, Katarina E. Heyden, Gaël Cagnone, Hitomi Yagi, Myriam Boeck, Deokho Lee, Victoria Hirst, Zhanqing Hua, Jeff Lee, Chaomei Wang, Katherine Neilsen, Jean-Sébastien Joyal, Martha S. Field, Zhongjie Fu   +14 more
doaj   +1 more source