Results 101 to 110 of about 86,914 (348)

Application of high flow nasal cannula oxygen therapy in children's bronchoscopy examination

Huli yanjiu
ObjectiveTo compare the oxygen therapy support effect between high flow nasal cannula oxygen therapy and double nasal cannula oxygen inhalation in children's bronchoscopy.MethodsConvenience sampling method was used to select 60 children who underwent ...
TANG Long, YANG Jia, NIU Mingyang, ZHANG Xiaowen, JIA Libo, WANG Yan   +5 more
doaj  

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

Effect of oxygen supplement during targeted temperature management on acute lung injury in the early stage of traumatic hemorrhagic shock

European Journal of Inflammation, 2020
Ideal concentrations of inhaled oxygen with regard to lung protection during early traumatic hemorrhagic shock (THS) remain unknown especially in the era of targeted temperature management (TTM). We speculated that a significant increase in oxygen supply
Tai-Wen Rao, Ye-Hua Shen, Xiao-Gang Zhao, Shou-Yin Jiang   +3 more
doaj   +1 more source

Inhalation of high-concentration hydrogen gas attenuates cognitive deficits in a rat model of asphyxia induced-cardiac arrest. [PDF]

, 2019
Cognitive deficits are a devastating neurological outcome seen in survivors of cardiac arrest. We previously reported water electrolysis derived 67% hydrogen gas inhalation has some beneficial effects on short-term outcomes in a rat model of global brain
Alexander, Bahjat, Bell, Chan, Cohan, Cui, Cui, Ge, Guo, Hayashida, Hayashida, Huang, Huang, Ji, Katsumata, Li, Lim, Moulaert, Nagatani, Neigh, Ohsawa, Ono, Reis, Roine, Schuhmann, Sugawara, Tamura, Tamura, Tian, Volpe, Wang, Xie, Zhao   +32 more
core   +2 more sources

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

BASIC MECHANISM OF HYPERBARIC OXYGEN IN INFECTIOUS DISEASE

Indonesian Journal of Tropical and Infectious Disease, 2016
Hyperbaric oxygen therapy (HBOT) is the inhalation of 100 percent oxygen inside a hyperbaric chamber that is pressurized to greater than 1 atmosphere (atm). HBOT causes both mechanical and physiologic effects by inducing a state of increased pressure and
Prihartini Widiyanti
doaj   +1 more source

Smoking Related Home Oxygen Burn Injuries: Continued Cause for Alarm [PDF]

, 2016
Background: Home oxygen therapy is a mainstay of treatment for patients with various cardiopulmonary diseases. In spite of warnings against smoking while using home oxygen, many patients sustain burn injuries.
Baker, Mary S., Bosslet, Gabriel T., Carlos, William G., McPherson, Katie A., Sood, Rajiv, Torke, Alexia M.   +5 more
core   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

PTG‐Dependent Glycogen Metabolic Dysfunction Drives Impaired Adipose Browning: A Novel Mechanism Linking PM2.5 to Metabolic Disorders

Advanced Science, EarlyView.
This study provides the first evidence that PM2.5 impairs iWAT browning via PTG‐mediated glycogen metabolism disruption, which is initiated by ADRB3 inhibition and subsequently triggers VEGFB upregulation. It thereby delineates the ADRB3‐PTG‐VEGFB axis as central to PM2.5‐induced metabolic dysfunction and identifies adipose glycogen metabolism as a ...
Limin Wang, Renjie Hu, Yanxi Chai, Ping He, Sanduo Li, Lisha Zhao, Wenbin Zhao, Lu Zhang, Li Qin, Ran Li, Xiaoli Hou, Qinghua Sun, Cuiqing Liu   +12 more
wiley   +1 more source

The method of inhalation therapy with micro-doses of mixtures noble\n gases with oxygen [PDF]

, 2021
A. Yu. Perov, Б. М. Овчинников, V. V. Parusov, A. V. Bobrovnikov, В. Г. Сафронова, Yu. D. Holodilin   +5 more
openalex   +2 more sources