Results 111 to 120 of about 57,040 (314)

Hyberbaric oxygen as sole treatment for severe radiation - induced haemorrhagic cystitis

open access: yesInternational Brazilian Journal of Urology
Purpose To examine the safety and efficacy of hyperbaric oxygen as the primary and sole treatment for severe radiation-induced haemorrhagic cystitis. Materials and methods Hyperbaric oxygen was prospectively applied as primary treatment in 38 patients
Athanasios Dellis   +4 more
doaj   +1 more source

Effect of nasal high-flow oxygen humidification on patients after cardiac surgery

open access: yesHeliyon, 2023
Background: Although high-flow humidified oxygen therapy (HFNC) has emerged as an important treatment for respiratory failure, few studies have reported on whether HFNC is appropriate for patients with hypoxemia after cardiac surgery, and the clinical ...
Fengzhen Wang   +5 more
doaj  

Engineering Extracellular Vesicles Derived from 3D Cultivation of BMSCs Enriched with HGF Ameliorate Sepsis‐Induced Lung Epithelial Barrier Damage

open access: yesAdvanced Science, EarlyView.
3D culture of MSCs upregulates gene expression of matrix metalloproteinases (MMPs), growth factors (GFs), and increases the production of extracellular vesicles (EVs). Proteomic analysis reveals 642 upregulated proteins in 3D‐EVs, including HGF. These 3D‐EVs, enriched with HGF, protect lung epithelial cells from apoptosis and barrier damage in septic ...
Yong Chen   +9 more
wiley   +1 more source

Automated Adjustment of the Fraction of Inspired Oxygen (FiO2) and the Time Spent in Normoxemia in Preterm Infants

open access: yesActa Médica Portuguesa
Introduction: The challenge of maintaining normoxemia in preterm infants undergoing respiratory support and oxygen therapy has led to the development of closed-loop automatic control systems for FiO2.
Gustavo Rocha   +3 more
doaj   +1 more source

Physiological impact of high-flow nasal cannula therapy on postextubation acute respiratory failure after pediatric cardiac surgery: a prospective observational study

open access: yesJournal of Intensive Care, 2017
Background Reintubation after pediatric cardiac surgery is associated with a high rate of mortality. Therefore, adequate respiratory support for postextubation acute respiratory failure (ARF) is important. However, little is known about the physiological
Naohiro Shioji   +7 more
doaj   +1 more source

Cardiac Slc25a49‐Mediated Energy Reprogramming Governs Doxorubicin‐Induced Cardiomyopathy through the G6P–AP‐1–Sln Axis

open access: yesAdvanced Science, EarlyView.
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan   +16 more
wiley   +1 more source

不同供氧方式高压氧治疗对手术治疗后卒中患者经皮氧分压影响的研究Effects of Different Oxygen Supply Methods during Hyperbaric Oxygen Therapy on the Transcutaneous Oximetry of Post-Surgery Stroke Patients

open access: yesZhongguo cuzhong zazhi
目的 评估不同供氧方式的高压氧治疗下,发病30 d内卒中术后患者经皮氧分压(transcutaneous oximetry,TcPO2)的变化。 方法 回顾性纳入2023年1月1日—2024年6月20日在高压氧科接受治疗的发病30 d内卒中术后患者,根据气道情况分为正常气道面罩加储气囊供氧(面罩组)和人工气道头罩供氧(头罩组)。高压氧治疗期间实时监测TcPO2,比较两种供氧方式下TcPO2变化。 结果 本研究共入选26例患者,面罩组和头罩组各13例。面罩组升压开始时TcPO2为(55.92±9.58)
任梓齐1,王勤芳1,2,刘亚玲1,王丛1,于秋红1 (REN Ziqi1, WANG Qinfang1,2, LIU Yaling1, WANG Cong1, YU Qiuhong1 )
doaj   +1 more source

Establishment of rat model for aspiration pneumonia and potential mechanisms

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Aspiration pneumonia was induced in Sprague Dawley rats by intratracheal instillation of hydrochloric acid (HCl, 1.5 μL/g.wt, pH = 1) followed by lipopolysaccharide (LPS, 20 μg/g.wt) after 1 h. The model reproduced hallmark features of acute lung injury, including histological lung damage, microvascular dysfunction, inflammation, hypoxemia, and ...
Hanbing Hu   +7 more
wiley   +1 more source

Identifying the optimal dose of cannabidiol by intrabuccal administration in Kramnik (C3HeB/FeJ) mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Cannabidiol (CBD) has numerous therapeutic properties, and is used to treat neurological conditions, such as neuroinflammation. However, the optimal dose of CBD to penetrate the brain requires further investigation. The primary aim of this study was to use a mouse model and the intrabuccal route for CBD administration to determine the optimal dose at ...
Oluwadara Pelumi Omotayo   +4 more
wiley   +1 more source

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