Results 101 to 110 of about 38,610 (331)
Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects
This review summarizes the latest progress in nanomaterials for X‐ray‐triggered cancer therapy, highlighting their various advantages such as targeted delivery, reduced side effects, and enhanced therapeutic efficacy. Abstract X‐rays, a form of ionizing radiation with high energy and significant penetration capability, are commonly used in clinical ...
Yuanchun Chen+6 more
wiley +1 more source
Biocatalysis. Biological systems for the production of chemicals [PDF]
Biocatalysis harnesses the catalytic potential of enzymes to produce building blocks and end-products for the pharmaceutical and chemical industry. Located at the interface between fermentation processes and petrol-based chemistry, biotransformation ...
Held, M.+3 more
core
A novel high-content immunofluorescence assay as a tool to identify at the single cell level γ-globin inducing compounds [PDF]
The identification of drugs capable of reactivating γ-globin to ameliorate β-thalassemia and Sickle Cell anemia is still a challenge, as available γ-globin inducers still have limited clinical indications.
Antonella Ronchi+14 more
core +4 more sources
Bioactives From Brown Algae: Antioxidant, Anti‐Inflammatory, Anticancer, and Antimicrobial Potential
This review explores key bioactives in brown algae and their antioxidant, anti‐inflammatory, anticancer, and antimicrobial properties. Covering studies from 2014 to 2024, it highlights their relevance in pharmaceuticals, nutraceuticals, cosmetics, and foods, while addressing challenges and future directions to unlock their full potential.
Irvin Fonseca‐Barahona+2 more
wiley +1 more source
National audienceLorsque l'on cherche a proteger les ecosystemes contre des agressions exterieures, en general liees a l'activite humaine, qui perturbent leurs mecanismes biologiques, l'idee la plus simple est de chercher au sein des organismes vivants ...
Vindimian, Eric
core +1 more source
Cardiac myocyte-specific knock-out of calcium-independent phospholipase A2γ (iPLA2γ) decreases oxidized fatty acids during ischemia/reperfusion and reduces infarct size [PDF]
Calcium-independent phospholipase A(2)γ (iPLA(2)γ) is a mitochondrial enzyme that produces lipid second messengers that facilitate opening of the mitochondrial permeability transition pore (mPTP) and contribute to the production of oxidized fatty acids ...
Abendschein, Dana+12 more
core +2 more sources
Diversity of ThDP‐Dependent Enzymes Forming Chiral Tertiary Alcohols
Chiral tertiary alcohols are widespread in nature and bioactive compounds; however, their asymmetric synthesis faces several challenges. This review outlines the toolbox of ThDP‐dependent enzymes able to produce tertiary alcohols through the formation of CC bond formation using ketones as acceptor substrates. Herein, the substrate scope, the diversity
Daniela Bjarnesen+4 more
wiley +1 more source
Oxylipins, a class of oxygenase-derived unsaturated fatty acids, are important signal molecules in many biological systems. Recent characterization of an Aspergillus flavus lipoxygenase gene, lox, revealed its importance in maintaining a density ...
Sigal Horowitz Brown+6 more
doaj +1 more source
Scaling beyond the laboratory exposes enzymes to new stresses. Exposure experiments reveal that dynamic gas‐liquid interfaces introduced by sparging or air entrainment during agitation are the main drivers of HMFO deactivation. Replacing bubbles with a membrane‐based bubble‐free aeration system dramatically enhances stability. These experiments provide
Amalie Vang Høst+4 more
wiley +1 more source
Does abscisic acid affect strigolactone biosynthesis? [PDF]
Strigolactones are considered a novel class of plant hormones that, in addition to their endogenous signalling function, are exuded into the rhizosphere acting as a signal to stimulate hyphal branching of arbuscular mycorrhizal (AM) fungi and germination
Adie+76 more
core +4 more sources