Results 111 to 120 of about 38,610 (331)

Acetylation‐Deacetylation‐Driven Natural Product Biosynthesis

ChemistryEurope, EarlyView.
This review summarizes the role of acetylation‐deacetylation in natural product biosynthesis, including acetylation followed by deacetylation after several biosynthetic steps, acetylation‐mediated rearrangement, acetylation‐triggered elimination, and the acetylation cycle as a regulatory mechanism. These processes are vital for the formation of complex
Huibin Wang, Ikuro Abe
wiley   +1 more source

The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. [PDF]

, 1968
R Tenhunen, Harvey S. Marver, R. Schmid
openalex   +1 more source

Spectroscopic Interrogation of Thiolate Hydrogen Bonding in the CO Sensor Protein CooA: Implications for Thiolate Ligation Stability and Cytochrome P450 Function

Chemistry – A European Journal, Accepted Article.
Cysteine (Cys) thiolate coordination is a unique ligation motif found in heme enzymes and small molecule sensors. Divergence between these two functional classes of heme thiolate proteins is a result of distinct hydrogen bonding interactions with the axial Cys(thiolate) ligand.
Brian R. Weaver, Richard J. Jodts, Brian M. Hoffman, Joshua A. Telser, Judith N. Burstyn   +4 more
wiley   +1 more source

Protozoan ALKBH8 oxygenases display both DNA repair and tRNA modification activities.

PLoS ONE, 2014
The ALKBH family of Fe(II) and 2-oxoglutarate dependent oxygenases comprises enzymes that display sequence homology to AlkB from E. coli, a DNA repair enzyme that uses an oxidative mechanism to dealkylate methyl and etheno adducts on the nucleobases ...
Daria Zdżalik, Cathrine B Vågbø, Finn Kirpekar, Erna Davydova, Alicja Puścian, Agnieszka M Maciejewska, Hans E Krokan, Arne Klungland, Barbara Tudek, Erwin van den Born, Pål Ø Falnes   +10 more
doaj   +1 more source

Interaction of Cysteamine Oxygenase with o‐Phenanthroline [PDF]

, 1969
D. Cavallinì, C. Cannella, E. Barboni, Alessandro Fiori, M. Marcucci   +4 more
openalex   +1 more source

Late‐Stage Amination of Peptides on the Solid Phase

Chemistry – A European Journal, EarlyView.
The introduction of amines into peptides via an on‐resin iodination‐substitution reaction sequence provides access to a wide variety of modifications, including amine‐based metal ligands. Primary, secondary, and aromatic amines, as well as heteroaromatic N‐nucleophiles, have been successfully incorporated into the reaction sequence.
Julian Brinkhofer, Marius Werner, Agon Kokollari, Shih‐Yu Pan, Christian Klein, Truc Lam Pham, Franziska Thomas   +6 more
wiley   +1 more source

Heme Oxygenase-1 Deficiency [PDF]

Indian Pediatrics, 2021
Manisha Madkaikar, Soumya Renji, Nitin Shah   +2 more
openaire   +5 more sources

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Bacterial oxidation of dimethylamine, a new mono-oxygenase reaction [PDF]

, 1969
Robert R. Eady, P Large
openalex   +1 more source

Terpenes and Terpenoids: How can we use them?

European Journal of Organic Chemistry, EarlyView.
The transition from petroleum‐based to renewable bio‐based chemicals has led to increased interest in terpenes and terpenoids. This overview highlights their chemistry, focusing on their reactivity and applications in polymerizations, total syntheses, pharmaceuticals, and bio‐based chemical conversions; promoting sustainable and green chemical ...
Jay Hanssens, Diego Meneses, Jordy M. Saya, Romano V. A. Orru   +3 more
wiley   +1 more source