Results 11 to 20 of about 13,927 (251)
Heme oxygenase-like dimetal oxidases and oxygenases. [PDF]
Biochem Soc TransAbstract The first heme oxygenase-like dimetal oxidase/oxygenase (HDO) was functionally validated through coordinated spectroscopic and rapid kinetic studies of the fatty acid decarboxylase UndA. The enzyme superfamily has since been recognized to orchestrate a variety of substrate transformations for natural product biosynthesis.
Skirboll SS, Ledinina AE, Makris TM.
europepmc +3 more sources
Applied Microbiology and Biotechnology, 2018 Natural rubber (NR), poly(cis-1,4-isoprene), is used in an industrial scale for more than 100 years. Most of the NR-derived materials are released to the environment as waste or by abrasion of small particles from our tires. Furthermore, compounds with isoprene units in their molecular structures are part of many biomolecules such as terpenoids and ...
Dieter Jendrossek, Jakob Birke
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Design principles for site-selective hydroxylation by a Rieske oxygenase
Nature Communications, 2022 SxtT and GxtA are Rieske oxygenases that are involved in paralytic shellfish toxin biosynthesis and catalyze monohydroxylation reactions at different positions on the toxin scaffold.
Jianxin Liu +6 more
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ENGINEERING NON-HEME MONO- AND DIOXYGENASES FOR BIOCATALYSIS
Computational and Structural Biotechnology Journal, 2012 Oxygenases are ubiquitous enzymes that catalyze the introduction of one or two oxygen atoms to unreactive chemical compounds. They require reduction equivalents from NADH or NADPH and comprise metal ions, metal ion complexes, or coenzymes in their active
Adi Dror, Ayelet Fishman
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Frontiers in Microbiology, 2017 Sewage waste represents an ecosystem of complex and interactive microbial consortia which proliferate with different kinetics according to their individual genetic as well as metabolic potential. We performed metagenomic shotgun sequencing on Ion-Torrent
Chandni Sidhu +3 more
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Palmitoylation of Metazoan Carotenoid Oxygenases
Molecules, 2020 Abundant in nature, carotenoids are a class of fat-soluble pigments with a polyene tetraterpenoid structure. They possess antioxidant properties and their consumption leads to certain health benefits in humans. Carotenoid cleavage oxygenases (CCOs) are a
Sheetal Uppal +3 more
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Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans
Scientific Reports, 2022 The JmjC family of 2-oxoglutarate dependent oxygenases catalyse a range of hydroxylation and demethylation reactions in humans and other animals. Jumonji domain-containing 7 (JMJD7) is a JmjC (3S)-lysyl-hydroxylase that catalyses the modification of ...
Rasheduzzaman Chowdhury +5 more
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Assays for the Detection of Rubber Oxygenase Activities
Bio-Protocol, 2017 Microbial biodegradation of rubber relies on extracellular rubber oxygenases that catalyze the oxidative cleavage of the double bond of the polyisoprene backbone into oligo-isoprenoids.
Wolf Röther +2 more
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Spin-orbit coupling effects in O(2) activation by cofactor-independent 2,4-dioxygenase [PDF]
The Ukrainian Biochemical Journal, 2019 The O2 (dioxygen) is paramagnetic molecule with two non-paired electron spins and triplet ground state (S = 1) while majority of organic molecules are diamagnetic species; they have all electron spins paired and the singlet ground state with the total ...
B. F. Minaev, R. R. Valiev
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Structural basis for divergent C–H hydroxylation selectivity in two Rieske oxygenases
Nature Communications, 2020 Rieske oxygenases are iron-dependent enzymes that catalyse C–H mono- and dihydroxylation reactions. Here, the authors characterise two cyanobacterial Rieske oxygenases, SxtT and GxtA that are involved in the biosynthesis of paralytic shellfish toxins and
April L. Lukowski +3 more
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