Results 21 to 30 of about 63,041 (289)
Nature’s Machinery, Repurposed: Expanding the Repertoire of Iron-Dependent Oxygenases
ACS Catalysis, 2020 Iron is an especially important redox-active cofactor in biology because of its ability to mediate reactions with atmospheric O2. Iron-dependent oxygenases exploit this earth-abundant transition metal for the insertion of oxygen atoms into organic ...
N. Dunham, F. Arnold
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Transcriptomic Analysis of Rhodococcus opacus R7 Grown on o-Xylene by RNA-Seq
Frontiers in Microbiology, 2020 Xylenes are considered one of the most common hazardous sources of environmental contamination. The biodegradation of these compounds has been often reported, rarer the ability to oxidize the ortho-isomer.
Jessica Zampolli +5 more
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ACS Central Science, 2020 AlkB and its human homologue AlkBH2 are Fe(II)- and 2-oxoglutarate (2OG)-dependent oxygenases that repair alkylated DNA bases occurring as a consequence of reactions with mutagenic agents.
semanticscholar +1 more source
Enzymology of Vertebrate Carotenoid Oxygenases
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 2020 Mammals and higher vertebrates including humans have only three members of the carotenoid cleavage dioxygenase family of enzymes. This review focuses on the two that function as carotenoid oxygenases.
E. Harrison, R. Kopec
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Enzyme Kinetics of Organic Contaminant Oxygenations
CHIMIA, 2020 Enzymatic oxygenations initiate biodegradation processes of many organic soil and water contaminants. Even though many biochemical aspects of oxygenation reactions are well-known, quantifying rates of oxidative contaminant removal as well as the extent ...
Charlotte E. Bopp +2 more
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Design principles for site-selective hydroxylation by a Rieske oxygenase
Nature Communications, 2022 SxtT and GxtA are Rieske oxygenases that are involved in paralytic shellfish toxin biosynthesis and catalyze monohydroxylation reactions at different positions on the toxin scaffold.
Jianxin Liu +6 more
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Biochemical Society Transactions, 2020 Fe(II)/2-oxoglutarate (2OG)-dependent oxygenases are a conserved enzyme class that catalyse diverse oxidative reactions across nature. In humans, these enzymes hydroxylate a broad range of biological substrates including DNA, RNA, proteins and some ...
Sally C. Fletcher, M. Coleman
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ENGINEERING NON-HEME MONO- AND DIOXYGENASES FOR BIOCATALYSIS
Computational and Structural Biotechnology Journal, 2012 Oxygenases are ubiquitous enzymes that catalyze the introduction of one or two oxygen atoms to unreactive chemical compounds. They require reduction equivalents from NADH or NADPH and comprise metal ions, metal ion complexes, or coenzymes in their active
Adi Dror, Ayelet Fishman
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Frontiers in Microbiology, 2017 Sewage waste represents an ecosystem of complex and interactive microbial consortia which proliferate with different kinetics according to their individual genetic as well as metabolic potential. We performed metagenomic shotgun sequencing on Ion-Torrent
Chandni Sidhu +3 more
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Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans
Scientific Reports, 2022 The JmjC family of 2-oxoglutarate dependent oxygenases catalyse a range of hydroxylation and demethylation reactions in humans and other animals. Jumonji domain-containing 7 (JMJD7) is a JmjC (3S)-lysyl-hydroxylase that catalyses the modification of ...
Rasheduzzaman Chowdhury +5 more
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