Results 51 to 60 of about 38,610 (331)
Antibacterial Siderophores of Pandoraea Pathogens and Their Impact on the Diseased Lung Microbiota
Genome mining of environmental and pathogenic Pandoraea species identified a conserved NRPS gene cluster and led to the discovery of novel siderophores, pandorabactins, which exert their antibacterial activity by depleting iron from competitors. Bioinformatic analysis of sputum from cystic fibrosis patients coupled with bioassays indicates that ...
Elena Herzog+8 more
wiley +2 more sources
Substrate Range and Genetic Analysis of Acinetobacter Vanillate Demethylase [PDF]
An Acinetobacter sp. genetic screen was used to probe structure-function relationships in vanillate demethylase, a two-component monooxygenase. Mutants with null, leaky, and heat-sensitive phenotypes were isolated.
Morawski, Birgit+2 more
core
Protein import into chloroplasts: new aspects of a well-known topic [PDF]
Protein import into plant chloroplasts is a fascinating topic that is being investigated by many research groups. Since the majority of chloroplast proteins are synthesised as precursor proteins in the cytosol, they have to be posttranslationally ...
Bölter, Bettina+2 more
core +1 more source
The Regulation of Trace Metal Elements in Cancer Ferroptosis
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang+5 more
wiley +1 more source
Characterization and Expression Analysis of Heme Oxygenase Genes from
Heme oxygenases (HOs) have a major role in phytochrome chromophore biosynthesis, and chromophores in turn have anti-oxidant properties. Plant heme oxygenases are divided into the HO1 sub-family comprising HO1, HO3, and HO4, and the HO2 sub-family, which ...
Takalani Mulaudzi-Masuku+5 more
doaj +1 more source
Controlled depolymerization of cellulose by light-driven lytic polysaccharide oxygenases
Lytic polysaccharide (mono)oxygenases (LPMOs) perform oxidative cleavage of polysaccharides. Here, the authors showed that the light-driven activity of LPMOs is dependent on hydrogen peroxide availability and can be controlled via the light intensity ...
Bastien Bissaro+3 more
doaj +1 more source
Carotenoids are isoprenoid pigments, and sources of vitamin A in humans. The first metabolic pathway for their synthesis is mediated by the enzymes β,β-carotene-15,15′-dioxygenase (BCO1) and β,β-carotene-9′,10′-dioxygenase (BCO2), which cleave ...
Anabela Martínez+3 more
doaj +1 more source
Enzymatic functionalization of carbon-hydrogen bonds [PDF]
The development of new catalytic methods to functionalize carbon–hydrogen (C–H) bonds continues to progress at a rapid pace due to the significant economic and environmental benefits of these transformations over traditional synthetic methods.
Arnold, Frances H.+2 more
core +1 more source
This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John+5 more
wiley +1 more source
Through the directed evolution of an underexploited nonheme Fe extradiol dioxygenase, we developed a unified cooperative photobiocatalytic strategy to allow for three types of enantioconvergent radical transformations, including azidation, thiocyanation, and isocyanation.
Liu‐Peng Zhao+8 more
wiley +2 more sources