Results 81 to 90 of about 38,938 (333)
Oxygen Activation by Mononuclear Mn, Co, and Ni Centers in Biology and Synthetic Complexes [PDF]
, 2017 The active sites of metalloenzymes that catalyze O2-dependent reactions generally contain iron or copper ions. However, several enzymes are capable of activating O2 at manganese or nickel centers instead, and a handful of dioxygenases exhibit activity ...
Fiedler, Adam T., Fischer, Anne A.
core +1 more source
Chromatin and oxygen sensing in the context of JmjC histone demethylases [PDF]
, 2014 Responding appropriately to changes in oxygen availability is essential for multicellular organism survival. Molecularly, cells have evolved intricate gene expression programmes to handle this stressful condition.
Abidi +139 more
core +4 more sources
Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy
Advanced Science, EarlyView.This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao +8 more
wiley +1 more source
Biocatalyst Screening with a Twist: Application of Oxygen Sensors Integrated in Microchannels for Screening Whole Cell Biocatalyst Variants [PDF]
, 2018 Selective oxidative functionalization of molecules is a highly relevant and often demanding reaction in organic chemistry. The use of biocatalysts allows the stereo- and regioselective introduction of oxygen molecules in organic compounds at milder ...
Fernandes, Ana C. +5 more
core +2 more sources
Advanced Science, EarlyView.The complex centered on Ghd7 binds to numerous carbon and nitrogen metabolism genes on the genome through the corresponding motifs and transactivates the transcriptional expression of these carbon and nitrogen metabolism genes. With the assistance of OsNAC42 and other unknown Ghd7‐interacting proteins, this complex can regulate different metabolic ...
Guangming Lou +23 more
wiley +1 more source
Enzymological and structural characterization of Arabidopsis thaliana heme oxygenase‐1
FEBS Open Bio, 2022 Arabidopsis thaliana heme oxygenase‐1 (AtHO‐1), a metabolic enzyme in the heme degradation pathway, serves as a prototype for study of the bilin‐related functions in plants.
Jia Wang +6 more
doaj +1 more source
The Regulation of Naphthalene Oxygenase in Pseudomonads [PDF]
Journal of General Microbiology, 1974 SUMMARY: Naphthalene oxygenase was induced in several pseudomonads when these were grown on salicylate as a carbon and energy source, or when salicylate was added to cultures growing on succinate. The enzyme was not induced in Pseudomonas strain NCIB9816 when this was grown in the presence of catechol, although after the addition of this compound to ...
K. M. Shamsuzzaman, E. A. Barnsley
openaire +3 more sources
, 1996 National audienceLorsque l'on cherche a proteger les ecosystemes contre des agressions exterieures, en general liees a l'activite humaine, qui perturbent leurs mecanismes biologiques, l'idee la plus simple est de chercher au sein des organismes vivants ...
Vindimian, Eric
core +1 more source
A novel high-content immunofluorescence assay as a tool to identify at the single cell level γ-globin inducing compounds [PDF]
, 2015 The identification of drugs capable of reactivating γ-globin to ameliorate β-thalassemia and Sickle Cell anemia is still a challenge, as available γ-globin inducers still have limited clinical indications.
Antonella Ronchi +14 more
core +4 more sources
Advanced Science, EarlyView.This study introduces two orthogonal sequencing methods, CMD1‐Deaminase sequencing (CD‐seq) and CMD1‐TET bisulfite sequencing (CT‐seq), that enable direct, independent detection of 5mC. Using these approaches together with ACE‐seq or TAB‐seq for 5hmC identification, the study reveals a significant reduction in 5hmC, but not 5mC, in the hippocampus of ...
Zi‐Xin Wang +15 more
wiley +1 more source