Results 51 to 60 of about 9,386 (216)

Plasma Oxylipins and Their Precursors Are Strongly Associated with COVID-19 Severity and with Immune Response Markers

Metabolites, 2022
COVID-19 is characterised by a dysregulated immune response, that involves signalling lipids acting as mediators of the inflammatory process along the innate and adaptive phases.
Naama Karu, Alida Kindt, Lieke Lamont, Adriaan J. van Gammeren, Anton A. M. Ermens, Amy C. Harms, Lutzen Portengen, Roel C. H. Vermeulen, Willem A. Dik, Anton W. Langerak, Vincent H. J. van der Velden, Thomas Hankemeier   +11 more
doaj   +1 more source

Acute Hypercapnia/Ischemia Alters the Esterification of Arachidonic Acid and Docosahexaenoic Acid Epoxide Metabolites in Rat Brain Neutral Lipids. [PDF]

, 2020
In the brain, approximately 90% of oxylipins are esterified to lipids. However, the significance of this esterification process is not known. In the present study, we (1) validated an aminopropyl solid phase extraction (SPE) method for separating ...
Bazinet, Richard P, Hammock, Bruce D, Metherel, Adam H, Newman, John W, Otoki, Yurika, Pedersen, Theresa, Taha, Ameer Y, Yang, Jun   +7 more
core   +1 more source

Oxylipins in plastidial retrograde signaling

Redox Biology, 2020
Oxylipins (compounds derived from the oxidation of polyunsaturated fatty acids) are essential in retrograde signaling emanating from plastids to the nucleus during plant developmental and stress responses. In this graphical review, we provide an overview of the chemical structure, biosynthesis and role of oxylipins, as both redox and hormonal signals ...
Paula Muñoz, Sergi Munné-Bosch
openaire   +3 more sources

A single meal has the potential to alter brain oxylipin content. [PDF]

, 2020
Our objective was to determine whether consumption of a single meal has the potential to alter brain oxylipin content. We examined the cerebrum of mice fed a single high-fat/high-sucrose Western meal or a low-fat/low-sucrose control meal, as well as ...
Aung, HH, Norman, JE, Otoki, Y, Rutledge, JC, Taha, AY, Zhang, Z   +5 more
core   +1 more source

Differential effects of EPA vs. DHA on postprandial vascular function and the plasma oxylipin profile in men [PDF]

, 2016
Our objective was to investigate the impact of EPA versus DHA, on arterial stiffness and reactivity, and underlying mechanisms (with a focus on plasma oxylipins), in the postprandial state.
Aedin Cassidy, Anne Marie Minihane, Armah, Asmar, Balakumar, Berry, Bonetti, Chong, Conquer, David Vauzour, Feelisch, Fischer, Flammer, Frömel, Hallund, Hickson, Huang, Ingrid Fleming, Jackson, Janner, Janner, Khader Awwad, Lauer, Lind, Lithander, Macready, Martin, Michaelis, Miller, Mitchell, Moerland, Mori, Morin, Morin, Mozaffarian, Mozaffarian, Mustafa, Neil Rigby, Noemi Tejera, Nürnberger, Pase, Psychogios, Pucci, Purcell, Ras, Rontoyanni, Ruiz-Lopez, Salem, Saravanan, Schebb, Schächinger, Seán McManus, Shearer, Shearer, Shen, Siasos, Strassburg, Vauzour, Vlachopoulos, Wang, Wang, West, Wilson, Ye   +63 more
core   +1 more source

Associated bacteria affect sexual reproduction by altering gene expression and metabolic processes in a biofilm inhabiting diatom [PDF]

, 2019
Diatoms are unicellular algae with a fundamental role in global biogeochemical cycles as major primary producers at the base of aquatic food webs. In recent years, chemical communication between diatoms and associated bacteria has emerged as a key factor
Bilcke, Gust, Cirri, Emilio, De Decker, Sam, De Veylder, Lieven, Osuna, Cristina, Pohnert, Georg, Vandepoele, Klaas, Vyverman, Wim, Werner, Markus, Werz, Oliver   +9 more
core   +2 more sources

De Novo Transcriptome Assembly and Gene Expression Profiling of the Copepod Calanus helgolandicus Feeding on the PUA-Producing Diatom Skeletonema marinoi

Marine Drugs, 2020
Diatoms are the dominant component of the marine phytoplankton. Several diatoms produce secondary metabolites, namely oxylipins, with teratogenic effects on their main predators, crustacean copepods.
Sneha Asai, Remo Sanges, Chiara Lauritano, Penelope K. Lindeque, Francesco Esposito, Adrianna Ianora, Ylenia Carotenuto   +6 more
doaj   +1 more source

The Synthesis of Pentyl Leaf Volatiles and Their Role in Resistance to Anthracnose Leaf Blight

Frontiers in Plant Science, 2021
Volatiles are important airborne chemical messengers that facilitate plant adaptation to a variety of environmental challenges. Lipoxygenases (LOXs) produce a bouquet of non-volatile and volatile oxylipins, including C6 green leaf volatiles (GLVs), which
Zachary Gorman, Jordan P. Tolley, Jordan P. Tolley, Hisashi Koiwa, Michael V. Kolomiets   +4 more
doaj   +1 more source

Lipid profile of Xylella fastidiosa Subsp. pauca associated with the olive quick decline syndrome [PDF]

, 2018
Lipids, components of the plasma and intracellular membranes as well as of droplets, provide different biological functions related to energy, carbon storage, and stress responses.
Manuel Salustri, Massimo Reverberi, Nicoletta Pucci, Simone Lucchesi, Stefania Loreti, Valeria Scala, Vanessa Modesti   +6 more
core   +2 more sources

The Partitioning of Newly Assimilated Linoleic and α-Linolenic Acids Between Synthesis of Longer-Chain Polyunsaturated Fatty Acids and Hydroxyoctadecaenoic Acids Is a Putative Branch Point in T-Cell Essential Fatty Acid Metabolism

Frontiers in Immunology, 2021
Longer-chain polyunsaturated fatty acids (LCPUFAs) ≥20 carbons long are required for leukocyte function. These can be obtained from the diet, but there is some evidence that leukocytes can convert essential fatty acids (EFAs) into LCPUFAs. We used stable
Johanna von Gerichten, Annette L. West, Nicola A. Irvine, Elizabeth A. Miles, Philip C. Calder, Philip C. Calder, Karen A. Lillycrop, Barbara A. Fielding, Graham C. Burdge   +8 more
doaj   +1 more source