Results 21 to 30 of about 1,133 (115)
Expression Cloning of an Oxysterol 7α-Hydroxylase Selective for 24-Hydroxycholesterol [PDF]
Journal of Biological Chemistry, 2000 Erik G Lund, David W Russell
exaly +2 more sources
Oxysterol 7α-Hydroxylase (CYP39A1) in the Ciliary Nonpigmented Epithelium of Bovine Eye [PDF]
Laboratory Investigation, 2003 Masamichi Ueda +2 more
exaly +2 more sources
Identification and Characterization of a Mouse Oxysterol 7α-Hydroxylase cDNA
Journal of Biological Chemistry, 1997 Margrit Schwarz +2 more
exaly +2 more sources
GPR183 Regulates 7α,25-Dihydroxycholesterol-Induced Oxiapoptophagy in L929 Mouse Fibroblast Cell
Molecules, 2022 7α,25-dihydroxycholesterol (7α,25-DHC) is an oxysterol synthesized from 25-hydroxycholesterol by cytochrome P450 family 7 subfamily B member 1 (CYP7B1) and is a monooxygenase (oxysterol-7α-hydroxylase) expressed under inflammatory conditions in various ...
Jae-Sung Kim +11 more
doaj +1 more source
Journal of Medical Case Reports, 2022 Background Congenital bile acid synthesis disorder type 3 caused by oxysterol 7α-hydroxylase deficiency is an extremely rare genetic liver disease. As it may cause rapid progression to end-stage liver disease, a high cautiousness in diagnosis and early ...
Weiqian Mo +7 more
doaj +1 more source
Pediatrics and Neonatology, 2020 Background: Inborn errors of bile acid metabolism (IEBAM) cause rare but treatable genetic disorders that can present as neonatal cholestasis or neurological diseases.
Ju-Yin Chen +13 more
doaj +1 more source
Antiviral Actions of 25-Hydroxycholesterol in Fish Vary With the Virus-Host Combination
Frontiers in Immunology, 2021 Cholesterol is essential for building and maintaining cell membranes and is critical for several steps in the replication cycle of viruses, especially for enveloped viruses. In mammalian cells virus infections lead to the accumulation of the oxysterol 25-
Mikolaj Adamek +19 more
doaj +1 more source
PLoS ONE, 2023 Macrophage inhibitory cytokine 1 (MIC-1), which is overproduced in various human cancers and associated with cachexia, acts on the hypothalamus to suppress appetite and reduce body weight.
Min Hee Kim +5 more
doaj +1 more source
Molecular Nutrition &Food Research, Volume 67, Issue 21, November 2023., 2023 Controlling cholesterol through dietary means is of great interest. The study reveals that consuming concentrated grape powder (GP) for 4 weeks lead to a reduction in circulating cholesterol levels by reducing cholesterol de novo biosynthesis in healthy individuals.
Jieping Yang +9 more
wiley +1 more source
24-Hydroxycholesterol is a substrate for hepatic cholesterol 7α-hydroxylase (CYP7A)
Journal of Lipid Research, 2000 (24S)-Hydroxycholesterol is formed from cholesterol in the brain and is important for cholesterol homeostasis in this organ. Elimination of (24S)-hydroxycholesterol has been suggested to occur in the liver but little is known about the metabolism of this
Maria Norlin +3 more
doaj +1 more source