Results 131 to 140 of about 7,074 (183)

Role of Nuclear Receptors on the Progression of Multiple Sclerosis: A Review. [PDF]

Cell Mol Neurobiol
Babaalizadeh B, Kalaki-Jouybari F, Abarghooi-Kahaki F, Afkhami H, Razavi ZS.   +4 more
europepmc   +1 more source

Microcystin-LR Drives Early NAFLD Pathogenesis via Hepatic Cholesterol Accumulation: Dysregulation of <i>Ldlr</i> and <i>Abcg1</i> Expression Uncoupled from <i>Srebp2</i>. [PDF]

Toxins (Basel)
Kawahara H, Koto Y, Hitsuda Y, Kurata K, Yoshikiyo K, Hashiguchi A, Maseda H, Okano K, Sugiura N, Shimizu K, Shimizu H.   +10 more
europepmc   +1 more source

Altered Lipid Metabolism in CNS Demyelination and Remyelination Are Key Elements Driving Progressive MS. [PDF]

Int J Mol Sci
Matejuk A, Matejuk S, Offner H, Vandenbark AA.   +3 more
europepmc   +1 more source

Role of oxysterol 4β-hydroxycholesterol and liver X receptor alleles in pre-eclampsia. [PDF]

Ann Med
Kaartinen L, Jääskeläinen T, Sliz E, Yazgeldi Gunaydin G, Wedenoja S, Katayama S, Kajantie E, Rinne V, Heinonen S, Kere J, Merikallio H, Hannele Laivuori submitted on behalf of FINNPEC group, Sliz E, submitted on behalf of FinnGen group, Laivuori H, Hukkanen J.   +15 more
europepmc   +1 more source

Oxysterols Suppress Release of DNA from Granulocytes into Extracellular Space After Stimulation with Phorbol Myristate Acetate. [PDF]

Biomedicines
Watanabe Y, Obama T, Makiyama T, Itabe H.   +3 more
europepmc   +1 more source

Rare Cholesterol Related Disorders – A Sterolomic Library for Diagnosis and Monitoring of Diseases

Griffiths WJ, Asgari MA, Yutuc E, Abdel-Khalik J, Crick PJ, Morris AA, Jones SA, Ghosh A, Hart C, Schöls L, Matysik S, Laina I, Pickrell WO, Moat SJ, Wang Y.   +14 more
europepmc   +1 more source

Oxysterols in Autoimmunity [PDF]

International Journal of Molecular Sciences, 2019
Cholesterol is a member of the sterol family that plays essential roles in biological processes, including cell membrane stability and myelin formation. Cholesterol can be metabolized into several molecules including bile acids, hormones, and oxysterols. Studies from the last few decades have demonstrated that oxysterols are not only active metabolites
Donovan Duc, Caroline Pot
exaly   +4 more sources

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Oxysterols and atherosclerosis

Atherosclerosis, 1999
Oxysterols are present in human atherosclerotic plaque and are suggested to play an active role in plaque development. Moreover, the oxysterol:cholesterol ratio in plaque is much higher than in normal tissues or plasma. Oxysterols in plaque are derived both non-enzymically, either from the diet and/or from in vivo oxidation, or (e.g.
A J, Brown, W, Jessup
openaire   +2 more sources

Oxysterols in Infectious Diseases

2023
Oxysterols have emerged as important bioactive lipids in the immune response to infectious diseases. This chapter discusses our current knowledge of oxysterols and their receptors in bacterial and viral infections of the respiratory and gastrointestinal tracts.
Cheng X, Foo, Michael B, Fessler, Katharina, Ronacher   +2 more
openaire   +2 more sources

Oxysterol binding protein

Chemistry and Physics of Lipids, 1985
A binding protein is described for certain oxygenated derivatives of cholesterol which suppress 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol synthesis in cultured mammalian cells. This protein is found in the cytosolic fraction of many cell types and is distinct from cytosolic proteins which bind cholesterol.
Taylor, F R, Kandutsch, A A
openaire   +2 more sources