Results 41 to 50 of about 24,748 (316)
µ-Opioid receptor antagonism facilitates the anxiolytic-like effect of oxytocin in mice
Translational PsychiatryMood and anxiety disorders are leading causes of disability worldwide and are major contributors to the global burden of diseases. Neuropeptides, such as oxytocin and opioid peptides, are important for emotion regulation.
Khalin E. Nisbett +2 more
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British Journal of Clinical Pharmacology, EarlyView.Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
The interplay of oxytocin and dopaminergic system: Effects on food consumption in broiler chickens
Poultry ScienceOxytocin play a crucial physiological role in regulating feed consumption and maintaining energy homeostasis. Numerous studies have highlighted the influence of central dopaminergic systems on appetite control; however, there is a lack of information ...
Hamed Zarei +2 more
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Biological Reviews, EarlyView.ABSTRACT Human life history is derived compared to that of our closest living relatives, the great apes. It has been suggested that these derived traits are causally related to aspects of our ecology, social behaviour and cognitive abilities. However, resolving this requires that we know the evolutionary trajectory of our distinctive pattern of growth,
Paola Cerrito +2 more
wiley +1 more source
Fetal Pain Perception: Legislative Assertions and Developmental Neuroscience
Annals of the Child Neurology Society, EarlyView.ABSTRACT Background Pain perception is a conscious experience, but neither pain nor consciousness is defined in the developing human fetus. Emergent consciousness may be regarded as a phenomenon that ultimately arises from an essential minimum of functional neuronal connectivity. Proposed U.S.
William D. Graf +9 more
wiley +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Binge eating disorder (BED) is maintained by increased food‐related incentive salience, which is reflected by an attentional bias for food. Oxytocin acutely attenuates this bias in patients with anorexia nervosa and reduces food intake in males with normal or increased body weight.
Julia Nannt +6 more
wiley +1 more source
Frontiers in Endocrinology, 2015 Oxytocin, a hormone most commonly associated with labor and lactation, may have a wide variety of physiological and pathological functions, which makes oxytocin and its receptor potential targets for drug therapy.
Seham eElabd, Ismail eSabry
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The Involvement of Oxytocin in the Subthalamic Nucleus on Relapse to Methamphetamine-Seeking Behaviour. [PDF]
PLoS ONE, 2015 The psychostimulant methamphetamine (METH) is an addictive drug of abuse. The neuropeptide oxytocin has been shown to modulate METH-related reward and METH-seeking behaviour.
Sarah Jane Baracz +2 more
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International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Restrictive eating disorders (EDs), including anorexia nervosa (AN) and atypical AN (Atyp‐AN), are often associated with cognitive rigidity that can impede treatment. The dorsolateral prefrontal cortex (dlPFC) plays a central role in cognitive control, but it remains unclear whether its activation during cognitive flexibility will ...
Adrienne L. Romer +19 more
wiley +1 more source
Structural basis for the activation and ligand recognition of the human oxytocin receptor
Nature Communications, 2022 Here, Waltenspühl et al. report the cryo-EM structure of active human oxytocin receptor in complex with oxytocin and with a heterotrimeric G protein, providing insights into this hormone system critically involved in the regulation of social behaviour ...
Yann Waltenspühl +5 more
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