Results 41 to 50 of about 50,893 (309)

Behavioral and epigenetic consequences of oxytocin treatment at birth. [PDF]

, 2019
Oxytocin is used in approximately half of all births in the United States during labor induction and/or augmentation. However, the effects of maternal oxytocin administration on offspring development have not been fully characterized.
Carter, CS, Connelly, JJ, Ferguson, EF, Ferris, CF, Kenkel, WM, Lillard, TS, Perkeybile, A-M, Pournajafi-Nazarloo, H, Wroblewski, KL, Yee, JR   +9 more
core  

Estrous behavior in dairy cows: identification of underlying mechanisms and gene functions [PDF]

, 2010
Selection in dairy cattle for a higher milk yield has coincided with declined fertility. One of the factors is reduced expression of estrous behavior. Changes in systems that regulate the estrous behavior could be manifested by altered gene expression ...
Beerda, B., Boer, H.M.T., Veerkamp, R.F., Woelders, H.   +3 more
core   +2 more sources

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

Involvement of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 3 in Oxytocin Neuronal Activity in Lactating Rats With Pup Deprivation

ASN Neuro, 2020
Oxytocin, a hypothalamic neuropeptide essential for breastfeeding, is mainly produced in oxytocin neurons in the supraoptic nucleus (SON) and paraventricular nucleus.
Dongyang Li, Haitao Liu, Xiaoyu Liu, Hongyang Wang, Tong Li, Xiaoran Wang, Shuwei Jia, Ping Wang, Yu-Feng Wang   +8 more
doaj   +1 more source

Neurosteroid involvement in threatened preterm labour

Endocrinology, Diabetes & Metabolism, 2021
Introduction The neurosteroid allopregnanolone modulates oxytocin expression in the brain, and its effects arise from its action on the GABAA receptor. Whether neurosteroid levels and the function of the GABAA receptor are involved in the risk of preterm
Sahruh Turkmen, Torbjörn Bäckström, Yvonne Kangas Flodin, Marie Bixo   +3 more
doaj   +1 more source

Glucocorticoids rapidly inhibit oxytocin-stimulated adrenocorticotropin release from rat anterior pituitary cells, without modifying intracellular calcium transients [PDF]

, 1993
Glucocorticoid hormones suppress the secretion of ACTH evoked by secretagogues such as CRF and arginine vasopressin. In this study, we investigated the effects of glucocorticoids on ACTH release induced by oxytocin (OT) and on intracellular free calcium ...
Dayanithi, G., Gratzl, Manfred, Link, H.
core   +1 more source

Microvascular Health as a Key Determinant of Organismal Aging

Advanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini, Andrea Uccelli, Francesca Mangili, Myriam Grunewald, Simone Bersini   +4 more
wiley   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source

Cerebellar damage with inflammation upregulates oxytocin receptor expression in Bergmann Glia

Molecular Brain
The cerebellum plays an important role in cognitive and social functioning. Childhood damage in the cerebellum increases the risk of autism spectrum disorder. Cerebellar inflammation induces social avoidance in mice.
Ayumu Inutsuka, Aisa Hattori, Masahide Yoshida, Yuki Takayanagi, Tatsushi Onaka   +4 more
doaj   +1 more source

Moxie begets MOXI: The journey to a novel hypothesis about Mu-opioid and OXytocin system Interactions

Comprehensive Psychoneuroendocrinology
This narrative review summarizes the early life of the author, Khalin E. Nisbett, and highlights the factors that led to her career in research and her development of two novel research hypotheses: the Mu-opioid and OXytocin system Interaction (MOXI ...
Khalin E. Nisbett
doaj   +1 more source