Results 31 to 40 of about 6,242 (170)

A Life Threatening Rash, an Unexpected Cause

open access: yesCase Reports in Dermatological Medicine, 2014
We describe a 74-year-old man with purpura fulminans and altered sensorium following an acute febrile illness. Intensive sepsis management was to no avail, until institution of doxycycline therapy following confirmation of scrub typhus.
Dhiraj Jain   +2 more
doaj   +1 more source

Pseudo-acne fulminans associated with oral isotretinoin [PDF]

open access: yes, 2014
Acne fulminans is a rare and serious condition characterized by the sudden onset of nodular and ulcerative acne lesions associated with systemic symptoms. It has been recognized a subset of patients with a sudden worsening of acne, often during treatment
Grando, Luciana Rosa   +2 more
core   +3 more sources

Difficulties in the treatment of acne fulminans – case report [PDF]

open access: yes, 2015
Introduction. Acne fulminans is the most severe form of acne. It occurs predominantly in boys in the peripubertal period. Skin lesions are accompanied by general symptoms and laboratory abnormalities. Objective.
Dorota Kozłowska   +2 more
core   +1 more source

Acne fulminans incapacitante Disabling Acne Fulminans [PDF]

open access: yes, 2011
Acne fulminans é uma manifestação rara, que pode ocorrer durante a evolução da acne vulgar, principalmente, em adolescentes masculinos. Uso de isotretinoína, testosterona, e reações imunológicas exacerbadas no organismo são desencadeantes relacionados ...
Zanelato,Tiago Pina   +9 more
core   +1 more source

Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel

open access: yesEmerging Infectious Diseases, 2018
We report a series of 5 case-patients who had Israeli spotted fever, of whom 2 had purpura fulminans and died. Four case-patients were given a diagnosis on the basis of PCR of skin biopsy specimens 3–4 days after treatment with doxycycline; 1 case ...
Regev Cohen   +6 more
doaj   +1 more source

Prenatal Etiology Diagnosis of Rare Compound Heterozygous PROC Gene Variants in a Fetus With Ocular Ultrasonic Anomaly Using Whole Exome Sequencing

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 7, July 2026.
This study first describes two rare compound heterozygous variants in PROC gene in a Chinese individual, which may broaden the mutation spectrum of thrombophilia due to protein C deficiency. ABSTRACT Background This study aims to present novel compound heterozygous PROC gene variants in a fetus.
Jianlong Zhuang   +3 more
wiley   +1 more source

Advancing tele‐physiology: A chest patch solution for continuous, non‐invasive remote monitoring in a hypoxic environment

open access: yesExperimental Physiology, Volume 111, Issue 7, Page 3280-3293, 1 July 2026.
Abstract Skin‐mounted sensors are thin, flexible and lightweight electronic devices that enable monitoring of multiple physiological parameters. The aim of this study was to provide pilot evidence for possible utilization of a sensorized patch for capturing the bodily response to hypoxia. The subsequent phases of the study comprised a case report and a
Danilo Bondi   +5 more
wiley   +1 more source

Neonatal Wet Gangrene With Early Auto‐Amputation in a Resource‐Limited Setting With Incomplete Etiologic Workup: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Neonatal limb gangrene with auto‐amputation is rare and often idiopathic. Early recognition, prompt referral, and thorough etiologic workup—despite resource limitations—are critical. Wet gangrene requires broad‐spectrum antibiotics, wound care, and timely surgical amputation to preserve growth plates and allow future prosthesis fitting.
Milki Tufa Feyisa   +7 more
wiley   +1 more source

An Uncommon Case of Ecthyma Gangrenosum in a Three‐Year‐Old Immunocompetent Child

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
The necrotic lesions on day 10. ABSTRACT Ecthyma gangrenosum (EG) is a rare cutaneous finding of Pseudomonas aeruginosa sepsis, typically in immunocompromised patients. We present EG with septic shock in a previously healthy three‐year‐old child who presented with rapidly progressing necrotic eschars and severe neutropenia.
Shobha Maharjan   +2 more
wiley   +1 more source

Analysis of the Phenotype and Gene Mutations of Two Families With Combined Mutations of Anticoagulant Protein Genes

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 4, April 2026.
In these two pedigrees, we identified distinct mutations in the AT and PC genes. Individuals harboring both mutations exhibited a significantly higher incidence of venous thrombosis. ABSTRACT Background AT and PC are key components of the anticoagulant system. Mutations in their encoding genes, SERPINC1 and PROC, can lead to insufficient protein levels
Yueli Guo   +5 more
wiley   +1 more source

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