Results 41 to 50 of about 1,976 (130)
Case Reports in Critical Care, Volume 2026, Issue 1, 2026.Streptococcal toxic shock syndrome (STSS) is a life‐threatening condition with increasing incidence and high mortality worldwide. It is characterised by hypotension and multiorgan failure, resultant of invasive group A Streptococcus (GAS) infections. Intravenous immunoglobulin (IVIG) has been proposed as an adjunctive therapy that reduces mortality in ...
Yuning Xue, Alex Yartsev, Lipi Buch
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Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami +2 more
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Invasive Meningococcal Disease in a Patient With Complement 7 Deficiency
Journal of General and Family Medicine, Volume 26, Issue 6, Page 646-649, November 2025.ABSTRACT Neisseria meningitidis can cause invasive meningococcal disease (IMD). Individuals with primary complement deficiencies are at a higher risk of developing IMD. However, cases of IMD associated with complement deficiency have rarely been reported in Japan.
Hiroaki Nishioka +2 more
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Necrotizing Fasciitis of Eyelid in Children: A Rare Complication of Varicella Infection
Clinical Case Reports, Volume 13, Issue 10, October 2025.ABSTRACT Necrotizing fasciitis (NF) of the eyelid is an extremely rare but severe complication of varicella zoster virus (VZV) infection in children. We present a case of an 8‐year‐old girl who developed necrotizing fasciitis of the left eyelid following varicella infection.
Govinda Bhandari +2 more
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Thrombosis in Brothers With Protein S Deficiency: Case Series
Clinical Case Reports, Volume 13, Issue 9, September 2025.ABSTRACT Hereditary protein S deficiency is a rare thrombophilia that increases the risk of venous thromboembolism (VTE), including thrombosis in unusual sites. Early diagnosis, familial screening, and long‐term anticoagulation are essential for preventing complications and improving outcomes.
Abate Bane Shewaye +5 more
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Purpura fulminans as the presenting manifestation in a patient with juvenile SLE
The Turkish Journal of Pediatrics, 2009 We present a 12-year-old girl with systemic lupus erythematosus and associated antiphospholipid syndrome who developed an unusual manifestation of purpura fulminans in an accelerated fashion.
Erkan Demirkaya +5 more
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Thrombosis Journal, 2019 Background Our objective was to study the phenotype of and molecular genetic mechanisms underlying congenital protein C (PC) deficiency in Chinese neonates.
Xiaoying Li +5 more
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Eye &ENT Research, Volume 3, Issue 1, Page 33-36, March 2026.
Armon Hadian +2 more
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Pulmonary Circulation, Volume 15, Issue 3, July 2025.ABSTRACT Pulmonary hypertension (PH) is a severe complication observed in pediatric patients after hematopoietic cell transplantation or chemotherapy. A review of records at Hokkaido University Hospital (2014–2024) identified four cases of PH, each with different etiologies, including pulmonary arterial hypertension, pulmonary veno‐occlusive disease ...
Ayako Chida‐Nagai +5 more
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The Turkish Journal of Pediatrics, 2002 Purpura fulminans is a rare but dramatic disease which occurs most commonly during or after an infection. It is characterized by extensive involvement of the skin and extremities and involvement of visceral organs.
Cengiz Canpolat, Mustafa Bakir
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