Results 61 to 70 of about 55,777 (181)

Purpura Fulminans in a Patient With Septic Shock due to Escherichia coli Bacteremia With Emphysematous Pyelitis

open access: yesCureus, 2021
Purpura fulminans (PF) is a rapidly fatal disorder predominantly encountered in patients with an acquired deficiency of physiologic anticoagulants due to severe sepsis and septic shock with disseminated intravascular coagulation (DIC).
Maria del Mar Morales Hernandez   +4 more
semanticscholar   +1 more source

Edema agudo hemorrágico da infância: relato de caso e comparação com meningococcemia [PDF]

open access: yes, 2017
This paper aims at reporting the case of a 1 year and 8 months old child who was in a bad general state, and was admitted at the emergency room while going through hypovolemic shock, with acute hemorrhagic edema of infancy (AHEI) or its variant: Henoch -
Caixeta, Mariana Figueiredo   +3 more
core   +2 more sources

Recognition and Management of Acute Purpura Fulminans: A Case Report of a Complication of Neisseria meningitidis Bacteremia

open access: yesCureus, 2021
Purpura fulminans (PF) is a rare, potentially fatal complication of disseminated intravascular coagulation that is commonly associated with severe bacterial infections such as those caused by the bacterium Neisseria meningitidis.
Michael C. Kim, Jaimin R. Patel
semanticscholar   +1 more source

Successful Treatment of Severe Purpura Fulminans With Anakinra

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Purpura fulminans (PF) is a rare, often fatal pediatric condition characterized by intravascular thrombosis and hemorrhagic infarction of the skin. A timely diagnosis and treatment are paramount to prevent the involvement of internal organs, causing disseminated intravascular coagulation and gangrene of the extremities.
Francesco Zulian   +4 more
wiley   +1 more source

Low-frequency inherited complement receptor variants are associated with purpura fulminans.

open access: yesBlood, 2023
Extreme disease phenotypes can provide key insights into the pathophysiology of common conditions, but studying these patients is challenging due to their rarity and the limited statistical power of existing methods.
Bendapudi PK   +27 more
europepmc   +2 more sources

The use of negative-pressure wound therapy over a cultured epithelial autograft for full-thickness wounds secondary to purpura fulminans in an infant

open access: yesArchives of Plastic Surgery, 2021
Purpura fulminans is a serious condition that can result in severe morbidity in the pediatric population. Although autologous skin grafts remain the gold standard for the coverage of partial- to full-thickness wounds, they have several limitations in ...
Benjamin Kah Liang Goh   +6 more
doaj   +1 more source

Postinfectious purpura fulminans: A case report.

open access: yesArchivos Argentinos de Pediatria
Acquired postinfectious purpura fulminans is a rare, acute, and severe disease characterized by skin necrosis associated with disseminated intravascular coagulation (DIC) in the absence of active infection or previous coagulation disorders.
Romina F Pombar   +4 more
semanticscholar   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami   +2 more
wiley   +1 more source

Invasive Meningococcal Disease in a Patient With Complement 7 Deficiency

open access: yesJournal of General and Family Medicine, Volume 26, Issue 6, Page 646-649, November 2025.
ABSTRACT Neisseria meningitidis can cause invasive meningococcal disease (IMD). Individuals with primary complement deficiencies are at a higher risk of developing IMD. However, cases of IMD associated with complement deficiency have rarely been reported in Japan.
Hiroaki Nishioka   +2 more
wiley   +1 more source

Púrpura fulminans [PDF]

open access: yes, 2005
We repon a case of a 65 year-old woman with Purpura fulminans secondary to Disseminated Intravascular Coagulation associated to urinary sepsis. We review the associated literature.Presentamos el caso de una mujer de 65 años con Púrpura fulminante ...
Núñez R., Rodrigo   +2 more
core   +1 more source

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