Results 191 to 200 of about 19,519,160 (297)

Les P-bodies [PDF]

médecine/sciences, 2018
Maïté Courel, Marianne Bénard, Michèle Ernoult-Lange, Racha Chouaib, Arnaud Hubstenberger, Michel Kress, Dominique Weil   +6 more
openaire   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Plant P-bodies in post-transcriptional control: Composition, dynamics, and context-dependent roles. [PDF]

Plant Commun
Matinahmadi A, Zayani Z, Majewska K, Smoliński DJ.   +3 more
europepmc   +1 more source

Specialized germline P-bodies are required to specify germ cell fate in Caenorhabditis elegans embryos.

Development, 2022
Cassani M, Seydoux G.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

RNA helicase DDX6 governs ASC speck formation in P-bodies and the transition to stress granules via phase separation during inflammasome activation. [PDF]

Cell Discov
Mao R, Liu Y, Fan Z, Li Y, Yang L, Xie Q, Dong HP, Bi M, Gao C, Yang Z, Xu T, Qi X.   +11 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Impact cratering experiments into highly porous bodies

, 2011
Asteroids represent both an opportunity and a risk. Their pristine environment captures the early collision evolution of the solar system; while their inherent ground impact potential could result in the mass extinction of life.
Vasile, Massimiliano, Gibbings, Alison
core  

The ubiquitin ligase Nedd4-2 promotes localization of DNMBP/Tuba to P-bodies under hyperosmotic stress. [PDF]

J Biol Chem
Liu Z, Jiang C, Yeung F, Raught B, Rotin D.   +4 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source