Results 101 to 110 of about 856,465 (267)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Symphysis-fundal height measurements in predicting fetal macrosomia

open access: yesInternational Journal of Medicine and Health Development, 2000
The predictive value of symphysio-funtfai height(SFH) measurements in fetal macrosomia was evaluated in a prospective cross-sectional study of 378 consecutive parturients at the University of Nigeria Teaching Hospital, Enugu, Eastern Nigeria over a three
H E Onah
doaj  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Curves on a quadric surface over $\overline{\mathbb {F}}_p$

open access: yesLe Matematiche, 2012
Here (following a paper by Giuffida, Maggioni and Re) we study the existence of curve $C\in \vert \mathcal {O}_{\mathbb {P}^1\times \mathbb {P}^1}(a,b)\vert$defined over small fields and with $h^0(C,\mathcal {O}_C(x,y))\cdot h^1(C, \mathcal {O}_C(x,y))=0$
Edoardo Ballico
doaj  

Evaluation of Pile Lateral Bearing Capacity-Based on Cone Penetration Test Results

open access: yesAdvances in Civil Engineering
To analyze the bearing capacity of pile foundations under horizontal loads, a new method based on the piezocone penetration test (CPTU) data for calculating pile p-y curves was proposed.
Yi He   +4 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Prediksi Kurva P-h dan Nilai Kekerasan pada Indentasi Bulat Berbasis Pendekatan Tegangan Representatif (?r)

open access: yesJurnal Energi Dan Manufaktur, 2016
Abstrak: Dalam penelitian ini model elemen hingga untuk indentasi bulat (Spherical) telah dikembangkan dan divalidasi. Sebuahpendekatan untuk memprediksi kurva P-h dari sifat material konstitutif telah dikembangkan dan diuji berdasarkanhubungan antara ...
I Nyoman Budiarsa
doaj  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

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