Results 11 to 20 of about 145,240 (241)

Compensating P. falciparum artemisinin resistance [PDF]

Cell Host & Microbe, 2021
Amino acid deprivation from reduced hemoglobin degradation in Pfkelch13 artemisinin-resistant parasites reduces fitness. In this issue of Cell Host & Microbe, Mesén-Ramírez et al. decipher the role of nutrient permeable channel activity within the parasitophorous vacuolar membrane to compensate for this fitness cost in asexual blood-stage Plasmodium ...
Platon, Lucien, Cao, Jun, Menard, Didier
openaire   +3 more sources

P. falciparum Invasion and Erythrocyte Aging. [PDF]

Cells
Plasmodium parasites need to find red blood cells (RBCs) that, on the one hand, expose receptors for the pathogen ligands and, on the other hand, maintain the right geometry to facilitate merozoite attachment and entry into the red blood cell. Both characteristics change with the maturation of erythrocytes. Some Plasmodia prefer younger vs.
Alves-Rosa MF, Tayler NM, Dorta D, Coronado LM, Spadafora C.   +4 more
europepmc   +4 more sources

Extreme parasitemia in P falciparum malaria [PDF]

Blood, 2018
![Figure][1] A 27-year-old man developed high fever after returning from sub-Saharan Africa. Trying to overcome this febrile illness during his annual leave (winter season), he had medical home visits, but the fever was repeatedly misdiagnosed as a flulike illness and treated with ...
Ana, Branco, José, Melo-Cristino
openaire   +2 more sources

Antimalarial Evaluation of the Chemical Constituents Isolated from Dendrocalamus asper

Journal of the Turkish Chemical Society, Section A: Chemistry, 2021
Bamboo shoots of Dendrocalamus asper is very important for human health because of its high content of dietary fiber, low sugar, negligible amount of fat, rich in vitamins and minerals.
Kok Tong WONG, Hasnah OSMAN, Thaigarajan PARUMASİVAM, Jafri Malin ABDULLAH, Mohd. Zaheen HASSAN, Mohamad Nurul Azmi MOHAMAD TAİB   +5 more
doaj   +1 more source

Interactions and potential implications of Plasmodium falciparum-hookworm coinfection in different age groups in south-central Côte d'Ivoire [PDF]

, 2012
BACKGROUND: Given the widespread distribution of Plasmodium and helminth infections, and similarities of ecological requirements for disease transmission, coinfection is a common phenomenon in sub-Saharan Africa and elsewhere in the tropics. Interactions
A Spiegel, AA Righetti, AH Shankar, Ahou-Yah G. Koua, Aurélie A. Righetti, C Menendez, CJL Murray, D Filmer, DA Ross, DI Thurnham, DL Doolan, Dominik Glinz, EK N'Goran, EK N'Goran, Eliézer K. N'Goran, FC Hartgers, FK Grant, FP Mockenhaupt, Francis Mutuku, G Jones, G Weiss, GC Melo, HR Choudhury, J Langhorne, J Murray, JD Cook, JG Erhardt, JK Kung'u, JL Gorstein, Jürg Utzinger, KE Lyke, KP West Jr, L Brutus, L Serghides, Lukas G. Adiossan, M Nacher, M Zuk, MD Taylor, N Katz, NJ Yatich, NR de Silva, P Galan, PJ Hotez, Richard F. Hurrell, Rita Wegmüller, RJ Stoltzfus, RL Pullan, RM Maizels, RW Snow, S Brooker, S Brooker, SL Becker, Sébastien Niamké, Y Dror   +53 more
core   +15 more sources

MOLECULAR-GENETIC MECHANISMS OF PLASMODIUM FALCIPARUM VIRULENCE AND TROPICAL MALARIA PATHOGENESIS

Журнал инфектологии, 2018
There is introduced the analysis of molecular-genetic mechanisms of tropical malaria pathogenesis and P. falciparum virulence. It is shown, that pathogenesis of tropical malaria is associated with the properties of red blood cells membrane surface (RBCs ...
A. N. Uskov, A. I. Soloviev, V. Yu. Kravtsov, R. V. Gudkov, E. V. Kolomoets, A. E. Levkovskiy   +5 more
doaj   +1 more source

Limited polymorphism in k13 gene of Plasmodium falciparum and k12 of Plasmodium vivax isolates imported from African and Asian countries between 2014 and 2019 in Hangzhou city, China

BMC Infectious Diseases, 2021
Background Malaria causes major public health problems globally and drug resistance hinders its control and elimination. Molecular markers associated with drug resistance are considered as a beneficial tool to monitor the disease trends, evolution and ...
Xingyi Jin, Sujuan Zhu, Weimin Xu, Junfang Chen, Wei Ruan, Xiaoxiao Wang   +5 more
doaj   +1 more source

Spatial mapping and prediction of Plasmodium falciparum infection risk among school-aged children in Côte d'Ivoire [PDF]

, 2016
BACKGROUND: In Côte d'Ivoire, malaria remains a major public health issue, and thus a priority to be tackled. The aim of this study was to identify spatially explicit indicators of Plasmodium falciparum infection among school-aged children and to ...
Assi, Serge-Brice, Chammartin, Frédérique, Fantodji, Agathe, Houngbedji, Clarisse A., Hürlimann, Eveline, Koudou, Benjamin G., N'Dri, Prisca B., N'Goran, Eliézer K., Raso, Giovanna, Silué, Kigbafori D., Soro, Gotianwa, Utzinger, Jürg, Vounatsou, Penelope, Yapi, Richard B.   +13 more
core   +5 more sources

Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum [PDF]

, 2009
Plasmodium falciparum, the Apicomplexan parasite that is responsible for the most lethal forms of human malaria, is exposed to radically different environments and stress factors during its complex lifecycle.
Annette N. Chiang, Banumathy, Billy W. Day, Botha, Brian P. Mead, Chiu, Corinne Schneider, Craig, David A. Fidock, Donna M. Huryn, Ekland, Fernandez-Saiz, Fewell, Fewell, Fewell, Fidock, Frydman, Hartl, Hunt, Jeffrey L. Brodsky, Jiang, Juan-Carlos Valderramos, Maier, Matambo, Mayer, McClellan, McKerrow, Michael G. Klein, Midorikawa, Nadeau, Noedl, Pavithra, Pecoul, Peter Wipf, Raghavan Balachandran, Raj J. Chovatiya, Ramya, Rodina, Samantha L. Bell, Shonhai, Shonhai, Sidhu, Tang, Tonkin, Wellems, Werner, Wright, Xiaojiang S. Chen, Youker   +48 more
core   +1 more source

Erythrocyte binding peptides: a story in the search for a malaria vaccine [PDF]

Exploration of Drug Science
Merozoite invasion of erythrocytes relies on molecular interactions between parasite and host proteins, making these proteins potential therapeutic targets.
Mauricio Urquiza-Martinez, Daniela Benavides-Rubio, Fanny Guzmán-Quimbayo   +2 more
doaj   +1 more source