Results 21 to 30 of about 24,188,006 (246)

Limited polymorphism in k13 gene of Plasmodium falciparum and k12 of Plasmodium vivax isolates imported from African and Asian countries between 2014 and 2019 in Hangzhou city, China

BMC Infectious Diseases, 2021
Background Malaria causes major public health problems globally and drug resistance hinders its control and elimination. Molecular markers associated with drug resistance are considered as a beneficial tool to monitor the disease trends, evolution and ...
Xingyi Jin, Sujuan Zhu, Weimin Xu, Junfang Chen, Wei Ruan, Xiaoxiao Wang   +5 more
doaj   +1 more source

Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay. [PDF]

, 2011
The diversity in the Plasmodium falciparum genome can be used to explore parasite population dynamics, with practical applications to malaria control.
Abdoulaye Djimde, Newbold, CI, Steven M Kiara, MacInnis, B, Jiang Hongying, Amaratunga, Chanaki, Mangano Valentina, Panos Deloukas, Socheat, Duong, Kirk Rockett, Jiang, H, Kivinen, K, MacInnis Bronwyn, Borrmann Steffen, Kwiatkowski, DP, Kiara Steven M., Kwiatkowski, Dominic, Pascal Michon, Valentina Mangano, Dominic P Kwiatkowski, Kwiatkowski Dominic P., Taane G Clark, Djimde Abdoulaye, Christopher I. Newbold, Borrmann, S, Deloukas, P, Rockett, K, Su, X-Z, Dominic P. Kwiatkowski, Nicholas J White, Imwong, Mallika, Ouedraogo, JB, Anderson, Timothy, Nicholas J. White, White Nicholas J., Zongo Issaka, Campino, S, Taane G. Clark, MacInnis, Bronwyn, Auburn Sarah, Clark, Taane G, Clark, TG, Newbold, Christopher, Nosten, François, Issaka Zongo, Nzila, A, Rockett Kirk, Gwilliam Rhian, Kevin Marsh, Djimde, Abdoulaye, Newbold, Christopher I, Xin-Zhuan Su, Kivinen, Katja, Amaratunga Chanaki, Rhian Gwilliam, Nosten François, Susana Campino, White, Nicholas J, Sarah Auburn, Fairhurst, Rick M, Michon, P, Nzila, Alexis, Gwilliam, Rhian, Mueller, Ivo, Siba, P, Doumbo Ogobara K., Ivo Mueller, Marsh, K, Zongo, Issaka, Chanaki Amaratunga, Timothy Anderson, Christopher I Newbold, Imwong Mallika, Jean-Bosco Ouedraogo, Clark Taane G., Alexis Nzila, Socheat Duong, Imwong, M, Anderson, T, Kiara, SM, White, NJ, Marsh, Kevin, Jean Bosco Ouedraogo, Fairhurst, RM, Steven M. Kiara, Michon, Pascal, Doumbo, Ogobara K, Deloukas, Panos, Marsh Kevin, Su, Xin-Zhuan, Djimde, A, Peter Siba, Siba, Peter, Mueller, I, Mallika Imwong, Ogobara K. Doumbo, Anderson Timothy, Hongying Jiang, White, Nicholas, Gwilliam, R, Katja Kivinen, Kiara, Steven M, Michon Pascal, Mangano, V, Siba Peter, Kivinen Katja, Zongo, I, Mueller Ivo, Campino Susana, Rick M. Fairhurst, Amaratunga, C, Newbold Christopher I., Auburn, Sarah, Xin Zhuan Su, Auburn, S, Rockett, Kirk, Bronwyn Macinnis, Nzila Alexis, Duong Socheat, François Nosten, Nosten, F, Su, XZ, Ouedraogo Jean-Bosco, Ouedraogo, J-B, Ogobara K Doumbo, Campino, Susana, Socheat, D, Jiang, Hongying, Doumbo, OK, Su Xin-Zhuan, Mangano, Valentina, Rick M Fairhurst, Ouedraogo, Jean-Bosco, Fairhurst Rick M., Borrmann, Steffen, Steffen Borrmann, Deloukas Panos, Kwiatkowski, Dominic P   +137 more
core   +1 more source

On peroxide antimalarials [PDF]

Journal of the Serbian Chemical Society, 2007
Several dicyclohexylidene tetraoxanes were prepared in order to gain a further insight into structure-activity relationship of this kind of antimalarials.
Opsenica Igor, Opsenica Dejan, Jadranin Milka, Smith Kirsten, Milhous Wilbur K., Stratakis Manolis, Šolaja Bogdan   +6 more
doaj   +1 more source

Erythrocyte binding peptides: a story in the search for a malaria vaccine [PDF]

Exploration of Drug Science
Merozoite invasion of erythrocytes relies on molecular interactions between parasite and host proteins, making these proteins potential therapeutic targets.
Mauricio Urquiza-Martinez, Daniela Benavides-Rubio, Fanny Guzmán-Quimbayo   +2 more
doaj   +1 more source

Combining antimalarial drugs and vaccine for malaria elimination campaigns: a randomized safety and immunogenicity trial of RTS,S/AS01 administered with dihydroartemisinin, piperaquine, and primaquine in healthy Thai adult volunteers

Human Vaccines & Immunotherapeutics, 2020
Introduction: RTS,S/AS01 is currently the most advanced malaria vaccine but provides incomplete, short-term protection. It was developed for use within the expanded program on immunizations (EPI) for African children. Another use could be adding mass RTS,
Lorenz von Seidlein, Borimas Hanboonkunupakarn, Podjanee Jittamala, Pongphaya Pongsuwan, Kesinee Chotivanich, Joel Tarning, Richard M. Hoglund, Markus Winterberg, Mavuto Mukaka, Pimnara Peerawaranun, Pasathorn Sirithiranont, Zoe Doran, Christian F. Ockenhouse, Karen Ivinson, Cynthia Lee, Ashley J. Birkett, David C. Kaslow, Pratap Singhasivanon, Nicholas P.J. Day, Arjen M. Dondorp, Nicholas J. White, Sasithon Pukrittayakamee   +21 more
doaj   +1 more source

Characterization of immunoglobulin G antibodies to Plasmodium falciparum sporozoite surface antigen MB₂ in malaria exposed individuals [PDF]

, 2009
Background MB2 protein is a sporozoite surface antigen on the human malaria parasite Plasmodium falciparum. MB2 was identified by screening a P. falciparum sporozoite cDNA expression library using immune sera from a protected donor immunized via the ...
James Anthony A, de la Vega, Patricia, John, Chandy C, Thanh V Nguyen, Nguyen, Thanh V, de la Vega, P, John B Sacci, Patricia de la Vega, James, Anthony A, Kang Angray S, John Chandy C, James, AA, Nguyen, T.V., Sacci, John B, Kang, A.S., Sacci John B, de la Vega, P., Nguyen Thanh V, Anthony A James, de la Vega Patricia, John, C.C., Kang, Angray S, Angray S Kang, Sacci, J.B., Patricia Vega, Chandy C John, John, CC, Nguyen, TV, Kang, AS, Jr, SJB, James, A.A.   +30 more
core   +1 more source

Plasmodium malariae contributes to high levels of malaria transmission in a forest–savannah transition area in Cameroon

Parasites & Vectors, 2023
Background Malaria control efforts are highly skewed towards Plasmodium falciparum while overlooking other Plasmodium species such as P. malariae. A better understanding of the role of Plasmodium species other than P.
Daniel Nguiffo-Nguete, Francis Nongley Nkemngo, Cyrille Ndo, Jean-Pierre Agbor, Stravensky T. Boussougou-Sambe, Luc Salako Djogbénou, Francine Ntoumi, Ayôla A. Adegnika, Steffen Borrmann, Charles S. Wondji   +9 more
doaj   +1 more source

The diagnostic and prognostic value of conventional and rapid diagnostic tools in malaria [PDF]

Al Ameen Journal of Medical Sciences, 2016
Background: The burden of malaria is raising all over the world and India is no exception. Despite well established treatment regimens and diagnostic tools, Malaria is thought to kill between1.1 to 2.7 million people worldwide each year.
Chandrakanth C.H
doaj  

Mefloquine in the Prophylaxis ofP. FalciparumMalaria [PDF]

Journal of Travel Medicine, 1995
Background: The objectives of this study were (1) to compare the efficacy of Lariam (mefloquine) with that of Fansimef (mefloquine, sulfadoxine, and pyrimethamine), Fansidar (sulfadoxine and pyrimethamine), chloroquine, and placebo in suppressing asexual parasitemia in semi-immune persons living in an area endemic for Plasmodium falciparum malaria; and
, Sossouhounto, , Soro, , Coulibaly, , Mittelholzer, , Stuerchler, , Haller   +5 more
openaire   +2 more sources

Genetic diversity of Plasmodium falciparum among school-aged children from the Man region, western Côte d'Ivoire [PDF]

, 2013
The genetic diversity of Plasmodium falciparum allows the molecular discrimination of otherwise microscopically identical parasites and the identification of individual clones in multiple infections. The study reported here investigated the P. falciparum
Silué, Kigbafori D., Giovanna Raso, Raso, Giovanna, Utzinger, Jürg, N. Guetta, Simon P., Mara, Sarah E., Marcel Tanner, Simon P N’Guetta, Sarah E Mara, Kigbafori D Silué, Ding, Xavier C., Eliézer K N’Goran, Xavier C Ding, Jürg Utzinger, N. Goran, Eliézer K., Tanner, Marcel   +15 more
core   +1 more source