Results 141 to 150 of about 20,775,577 (293)

Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang, Geeta Madhuri Bhuvanagiri, Megan Dulkanchainun, Cunyu Wang   +3 more
wiley   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source

Pathogenicity of <i>P. gingivalis</i> strains carrying clusters of specific polymorphic variants of peptidylarginine deiminase gene. [PDF]

Front Cell Infect Microbiol
Strzelec K, Dziedzic-Kowalska A, Ferenc K, Łazarz-Bartyzel K, Olszewska-Czyż I, Rąpalska I, Sieroń Ł, Aptekorz M, Romanik M, Mendrek B, Oleszko-Torbus N, Kowalczuk A, Kusz D, Kaczmarzyk T, Cześnikiewicz-Guzik M, Niemiec P, Wasik TJ, Gawron K.   +17 more
europepmc   +1 more source

Multi-omics insights reveal the remodeling of gut mycobiome with P. gingivalis. [PDF]

Front Cell Infect Microbiol, 2022
Chen S, Niu C, Lv W.
europepmc   +1 more source

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

Journal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw, Ren Jie Jacob Chew, Charlene Enhui Goh, Ali A. Abdulkareem, Dana T. Graves   +4 more
wiley   +1 more source

Macrophage activation and invasion by <i>P. gingivalis</i> is modulated by PPAD and accessory fimbriae subunits. [PDF]

J Oral Microbiol
Wielento A, Drapała DM, Terekhova M, Jacuła A, Artyomov MN, Kochan J, Hasegawa Y, Mizgalska D, Bagaitkar J, Grabiec AM, Potempa J.   +10 more
europepmc   +1 more source

Periodontitis and Rheumatoid Arthritis—Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
Periodontitis and rheumatoid arthritis are linked via the two‐hit model whereby early periodontal inflammation can lead to autoantibody production capable of interacting with inflamed synovial tissues. Subsequent systemic inflammation can exacerbate the periodontal inflammatory response and bacterial dysbiosis leading to further autoantibody production
Mark Bartold, Chia Wei Cheah, Rathna Devi Vaithilingam   +2 more
wiley   +1 more source

Intranasal MyD88-adjuvanted DNA vaccine against P. gingivalis in rat periodontitis. [PDF]

BMC Oral Health
Wang R, Li X, Chen B, Wang Y, Bai G.
europepmc   +1 more source

Periodontal Diseases as a Public Health Challenge: Rationale, Prevention, Equity, and Sustainable Care—A Global Call for Action

Journal of Periodontal Research, EarlyView.
Periodontal diseases affect over a billion people worldwide, yet remain weakly integrated into global non‐communicable disease agendas. We propose reorienting periodontal care around three public health opportunities—upstream prevention, diagnosis fit for both clinical and population use, and value‐based treatment—prioritizing prevention, value, and ...
Marco A. Peres, Lijian Jin, Gustavo G. Nascimento, Philip M. Preshaw, Eero Juhani Raittio, Dian Yi Chow, John Rong Hao Tay   +6 more
wiley   +1 more source

<i>P. gingivalis</i> induces endothelial dysfunction via mitochondrial fission dependent VDAC1-HK2 disassociation. [PDF]

J Oral Microbiol
Wang Y, Xu S, Zhuang Z, Tu C, Zhou Z, Chen T, Wu M, Lu B, Ye P, Fan X, Hu R, Deng H.   +11 more
europepmc   +1 more source