Results 141 to 150 of about 24,766 (261)

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

Journal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw, Ren Jie Jacob Chew, Charlene Enhui Goh, Ali A. Abdulkareem, Dana T. Graves   +4 more
wiley   +1 more source

Macrophage activation and invasion by <i>P. gingivalis</i> is modulated by PPAD and accessory fimbriae subunits. [PDF]

J Oral Microbiol
Wielento A, Drapała DM, Terekhova M, Jacuła A, Artyomov MN, Kochan J, Hasegawa Y, Mizgalska D, Bagaitkar J, Grabiec AM, Potempa J.   +10 more
europepmc   +1 more source

Periodontal Diseases as a Public Health Challenge: Rationale, Prevention, Equity, and Sustainable Care—A Global Call for Action

Journal of Periodontal Research, EarlyView.
Periodontal diseases affect over a billion people worldwide, yet remain weakly integrated into global non‐communicable disease agendas. We propose reorienting periodontal care around three public health opportunities—upstream prevention, diagnosis fit for both clinical and population use, and value‐based treatment—prioritizing prevention, value, and ...
Marco A. Peres, Lijian Jin, Gustavo G. Nascimento, Philip M. Preshaw, Eero Juhani Raittio, Dian Yi Chow, John Rong Hao Tay   +6 more
wiley   +1 more source

P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress. [PDF]

Int J Mol Sci, 2023
Verma A, Azhar G, Zhang X, Patyal P, Kc G, Sharma S, Che Y, Wei JY.   +7 more
europepmc   +1 more source

Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine, Yiorgos A. Bobetsis, Benjamin C. Shayo, Peter Milgrom, Phoebus N. Madianos   +4 more
wiley   +1 more source

Intranasal MyD88-adjuvanted DNA vaccine against P. gingivalis in rat periodontitis. [PDF]

BMC Oral Health
Wang R, Li X, Chen B, Wang Y, Bai G.
europepmc   +1 more source

Viruses, Periodontitis, and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
K. N. Stolte, Y. L. Hernandez‐Kapila, H. Dommisch   +2 more
wiley   +1 more source

USP22 knockdown attenuates <i>P. gingivalis</i>-induced EndoMT and CNS inflammation: a link between periodontitis and neuroinflammation. [PDF]

Front Neurosci
Wang H, Wang M, Shen J, Zhang H, Duan C.
europepmc   +1 more source

Ozonized Hydrogel and Chlorhexidine Gel for Peri‐Implant Mucositis: A 24‐Month Randomized Controlled Trial

Oral Diseases, EarlyView.
ABSTRACT Objective This randomized controlled trial evaluated the 24‐month effectiveness of a nonsurgical intervention for peri‐implant mucositis, comparing a 15% ozonated sunflower oil hydrogel with a 1% chlorhexidine gel. Methods Thirty patients with 360 peri‐implant mucositis sites were treated in a split‐mouth design, receiving both therapies in ...
Andrea Scribante, Maurizio Pascadopoli, Matteo Pellegrini, Marco Saturnino Lupi, Carlos Pérez‐Albacete Martínez, Andrea Butera   +5 more
wiley   +1 more source

CKIP-1 mediates P. gingivalis-suppressed osteogenic/cementogenic differentiation of periodontal ligament cells partially via p38 signaling pathway. [PDF]

J Oral Microbiol, 2023
Huang X, Xiao J, Wang H, Peng Y, Liu H, Ma L, Wang X, Cao Z.   +7 more
europepmc   +1 more source