Results 161 to 170 of about 24,766 (261)

Efficacy of a Mouthwash Containing Resveratrol in Reducing Halitosis-related P. gingivalis: A Randomized Triple-blind Trial. [PDF]

Oral Health Prev Dent
Abed Taher NA, Mahmood AA, Hussein HM.
europepmc   +1 more source

Efficacy of a Hyaluronic Acid‐Based Gel Versus 0.20% Chlorhexidine in Nonsurgical Periodontal Therapy: A Single‐Blind Randomized Clinical Trial

Oral Diseases, EarlyView.
ABSTRACT Objective To compare the adjunctive efficacy of a hyaluronic acid (HA) gel with 0.20% chlorhexidine (CHX) during nonsurgical periodontal therapy in periodontal patients over 6 months. Methods A single‐blind, randomized, controlled trial included 40 healthy, nonsmoking adults with periodontitis.
Andrea Scribante, Maurizio Pascadopoli, Matteo Pellegrini, Karyna Chekal, Andrea Butera   +4 more
wiley   +1 more source

Sulforaphene Mitigates Periodontitis by NRF2-Dependent Regulation of <i>P. gingivalis</i>-Induced Inflammatory Response and Bone Homeostasis. [PDF]

Food Sci Nutr
Yao H, Yu K, Jiang B, Liao Y, Zhao Y, Chen J, Li T, Yin M, Sheng Y, Ye W, Zhao B, Du M, Ji Y.   +12 more
europepmc   +1 more source

Kamishoyosan and Kamikihito protect against decreased KCC2 expression induced by the P. gingivalis lipopolysaccharide treatment in PC-12 cells and improve behavioral abnormalities in male mice. [PDF]

Heliyon, 2023
Tomita K, Oohara Y, Igarashi K, Kitanaka J, Kitanaka N, Tanaka KI, Roudkenar MH, Roushandeh AM, Sugimura M, Sato T.   +9 more
europepmc   +1 more source

Oxidative Stress–Driven Alterations in FoxO‐1 and MMP‐9 Activity in Smoking‐Associated Periodontitis

Oral Diseases, EarlyView.
ABSTRACT Objectives Smoking disrupts oxidative balance and is a major risk factor for periodontitis. Forkhead box protein O‐1 (FoxO‐1) regulates antioxidant defense, yet its contribution to smoking‐associated periodontal breakdown is unclear. This cross‐sectional case–control study assessed reactive oxygen species (ROS), matrix metalloproteinase‐9 (MMP‐
Fatma Oner, Fatma Soysal, Ceren Gokmenoglu, Muhittin A. Serdar, Zeliha Guney   +4 more
wiley   +1 more source

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

Porphyromonas gingivalis Outer Membrane Vesicles‐Associated DNA Triggers Inflammation by Inducing IL‐6 in Astrocytes

Molecular Oral Microbiology, EarlyView.
Pg releases OMVs which contain Pg genomic DNA. The Pg OMVs‐associated DNA is incorporated into astrocytes via endocytosis and increases IL‐6 mRNA expression via TLR9. These effects of Pg OMVs may induce neuroinflammation, which could contribute to the onset and progression of AD in periodontal disease.
Ayu Takai, Kaya Yoshida, Yuka Hiroshima, Ayu Ikuta, Mariko Seyama, Yuta Uemura, Hiromichi Yumoto, Kazumi Ozaki   +7 more
wiley   +1 more source

Biomimetic nanotherapy for <i>P. gingivalis</i>-infected oral squamous cell carcinoma: Photothermal therapy and immunoactivation <i>via</i> precise intracellular bacterial elimination. [PDF]

Int J Pharm X
Dai Z, Li Q, Guo L, Zhong K, Cheng J, Weng X, Cheng B.   +6 more
europepmc   +1 more source

Development of monoclonal antibodies against P. gingivalis Mfa1 and their protective capacity in an experimental periodontitis model. [PDF]

mSphere
Cao M, Wang S, Zhou S, Yan M, Zou Y, Cui Y, Lou X, Gao Y, Chen Y, Han Z, Qian Y, Chen J, Li X.   +12 more
europepmc   +1 more source