Results 161 to 170 of about 24,000,753 (244)

USP22 knockdown attenuates <i>P. gingivalis</i>-induced EndoMT and CNS inflammation: a link between periodontitis and neuroinflammation. [PDF]

Front Neurosci
Wang H, Wang M, Shen J, Zhang H, Duan C.
europepmc   +1 more source

Viruses, Periodontitis, and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte, Yvonne L. Hernandez‐Kapila, Henrik Dommisch   +2 more
wiley   +1 more source

CKIP-1 mediates P. gingivalis-suppressed osteogenic/cementogenic differentiation of periodontal ligament cells partially via p38 signaling pathway. [PDF]

J Oral Microbiol, 2023
Huang X, Xiao J, Wang H, Peng Y, Liu H, Ma L, Wang X, Cao Z.   +7 more
europepmc   +1 more source

Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi, Aaron Zander, Bradley Chan, Leila Syedmoradi, Dev Trivedi, Karolina Elżbieta Kaczor‐Urbanowicz, Fang Wei, Neeti Swarup, Trinity Chan, Mario Romandini, David T. W. Wong   +10 more
wiley   +1 more source

Bacterial-host interactions in periodontal prognosis: Role of <i>P. gingivalis</i> and IL-8. [PDF]

J Dent Sci
Lin YC, Renn TY, Lee CY, Teng NC, Huang YK.   +4 more
europepmc   +1 more source

The Oral‐Hepatic Axis: Epidemiological and Mechanistic Links Between Periodontal and Liver Diseases

Journal of Periodontal Research, EarlyView.
This review summarizes current epidemiological, clinical and mechanistic evidence linking periodontitis and chronic liver diseases, highlighting the oral‐gut‐liver axis, shared immunometabolic and nutritional pathways and opportunities for integrated preventive and therapeutic strategies.
Sinem Esra Sahingur, Kinga Grzech‐Leśniak, Samuel F. Suslavich, Janina Golob Deeb   +3 more
wiley   +1 more source

Targeted Inhibition of P. gingivalis OMV-derived TsRNA by tetrahedral framework nucleic acids promotes periodontal regeneration. [PDF]

J Nanobiotechnology
Cao Y, Li X, Jing L, Li F, Chen Y, Deng D, Zhang W, Liu F, Lin Y, Tian B, Zhou M, He X.   +11 more
europepmc   +1 more source

P. gingivalis Infection Upregulates PD-L1 Expression on Dendritic Cells, Suppresses CD8+ T-cell Responses, and Aggravates Oral Cancer. [PDF]

Cancer Immunol Res, 2023
Ren J, Han X, Lohner H, Hoyle RG, Li J, Liang S, Wang H.   +6 more
europepmc   +1 more source

The Dual Face of Fusobacterium nucleatum in Cancer: Foe, Friend or Both?

Journal of Periodontal Research, EarlyView.
Fusobacterium nucleatum has established interactions with cancers in humans. However, contrary to a traditional view that these interactions are uniformly pro‐tumoural, recent evidence suggests a more nuanced role, where contact‐dependent and contact‐independent mechanisms may support either tumour progression or restriction depending on tumour site ...
Anjali Chander, Huile Lim, Gilad Bachrach, Miguel Reis Ferreira   +3 more
wiley   +1 more source

Differential antimicrobial activity of two LL37 derivatives against periodontal bacteria, including enhanced efficacy against <i>P. gingivalis</i> in the presence of cigarette smoke. [PDF]

Front Microbiol
Keshavarz S, Hirschfeld J, Grant MM.
europepmc   +1 more source