Removal of CD5 on T cells alters their differentiation and cytokine production in an <i>in vitro</i> model investigating effects of <i>P. gingivalis</i> LPS on oral epithelial and immune cells. [PDF]
Moreno C +4 more
europepmc +1 more source
Kamishoyosan and Kamikihito protect against decreased KCC2 expression induced by the P. gingivalis lipopolysaccharide treatment in PC-12 cells and improve behavioral abnormalities in male mice. [PDF]
Tomita K +9 more
europepmc +1 more source
ABSTRACT Objective To compare the adjunctive efficacy of a hyaluronic acid (HA) gel with 0.20% chlorhexidine (CHX) during nonsurgical periodontal therapy in periodontal patients over 6 months. Methods A single‐blind, randomized, controlled trial included 40 healthy, nonsmoking adults with periodontitis.
Andrea Scribante +4 more
wiley +1 more source
Sulforaphene Mitigates Periodontitis by NRF2-Dependent Regulation of <i>P. gingivalis</i>-Induced Inflammatory Response and Bone Homeostasis. [PDF]
Yao H +12 more
europepmc +1 more source
GDF15 Supports the Inflammatory Response of PdL Fibroblasts Stimulated by P. gingivalis LPS and Concurrent Compression. [PDF]
Stemmler A +5 more
europepmc +1 more source
Oxidative Stress–Driven Alterations in FoxO‐1 and MMP‐9 Activity in Smoking‐Associated Periodontitis
ABSTRACT Objectives Smoking disrupts oxidative balance and is a major risk factor for periodontitis. Forkhead box protein O‐1 (FoxO‐1) regulates antioxidant defense, yet its contribution to smoking‐associated periodontal breakdown is unclear. This cross‐sectional case–control study assessed reactive oxygen species (ROS), matrix metalloproteinase‐9 (MMP‐
Fatma Oner +4 more
wiley +1 more source
Mitigation of P. gingivalis-exacerbated intestinal inflammation by paeoniflorin through alteration of the gut microbiota. [PDF]
Qu R +8 more
europepmc +1 more source
Effect of a Nanostructured Titanium Surface on Gingival Cell Adhesion, Viability and Properties against P. gingivalis. [PDF]
Mukaddam K +9 more
europepmc +1 more source
ABSTRACT Background This cross‐sectional study aimed to evaluate the influence of vitamin D and glycaemic control on the severity of periodontitis in Cameroonian type 2 diabetics (T2D) and to identify the determinants of severe periodontitis (SP). Methods Vitamin D concentration and blood glucose control were determined by measuring serum levels of 25 ...
Lawrence Essama Eno Belinga +8 more
wiley +1 more source
Lys-specific gingipain (Kgp) of <i>P. gingivalis</i> promotes viral infection by disabling the interferon pathway. [PDF]
Dobosz E +11 more
europepmc +1 more source

