Mitigation of P. gingivalis-exacerbated intestinal inflammation by paeoniflorin through alteration of the gut microbiota. [PDF]
Qu R +8 more
europepmc +1 more source
ABSTRACT Objective To compare the adjunctive efficacy of a hyaluronic acid (HA) gel with 0.20% chlorhexidine (CHX) during nonsurgical periodontal therapy in periodontal patients over 6 months. Methods A single‐blind, randomized, controlled trial included 40 healthy, nonsmoking adults with periodontitis.
Andrea Scribante +4 more
wiley +1 more source
Lys-specific gingipain (Kgp) of <i>P. gingivalis</i> promotes viral infection by disabling the interferon pathway. [PDF]
Dobosz E +11 more
europepmc +1 more source
Oxidative Stress–Driven Alterations in FoxO‐1 and MMP‐9 Activity in Smoking‐Associated Periodontitis
ABSTRACT Objectives Smoking disrupts oxidative balance and is a major risk factor for periodontitis. Forkhead box protein O‐1 (FoxO‐1) regulates antioxidant defense, yet its contribution to smoking‐associated periodontal breakdown is unclear. This cross‐sectional case–control study assessed reactive oxygen species (ROS), matrix metalloproteinase‐9 (MMP‐
Fatma Oner +4 more
wiley +1 more source
P. Gingivalis LPS Drives Osteoclastogenesis and Impairs Osteoblast Differentiation by Suppressing Sema3A/Nrp1 Via TLR-4. [PDF]
Feng J, Fu D, Phan S, Hu X, Xing Q.
europepmc +1 more source
ABSTRACT Background This cross‐sectional study aimed to evaluate the influence of vitamin D and glycaemic control on the severity of periodontitis in Cameroonian type 2 diabetics (T2D) and to identify the determinants of severe periodontitis (SP). Methods Vitamin D concentration and blood glucose control were determined by measuring serum levels of 25 ...
Lawrence Essama Eno Belinga +8 more
wiley +1 more source
A Novel Role for the Small Molecule Cinnamaldehyde in Protecting Against <i>P. gingivalis</i>-Induced Endothelial Dysfunction in Mice: Involvement of PPARγ/Akt/eNOS and Nrf2/ARE Signaling. [PDF]
Sampath C +4 more
europepmc +1 more source
ABSTRACT Objective This study aimed to evaluate (i) the presence of red complex bacteria in carotid atheroma plaques of dentate and edentulous patients and (ii) the possible relationship between mitochondrial DNA copy number (mtDNA‐cn), an indicator of mitochondrial function, and periodontal disease.
Ayşe Toraman +4 more
wiley +1 more source
Erratum to 'Biomimetic nanotherapy for <i>P. gingivalis</i>-infected oral squamous cell carcinoma: Photothermal therapy and immunoactivation via precise intracellular bacterial elimination' [International Journal of Pharmaceutics: X 10 (2025) 100438]. [PDF]
Dai Z +6 more
europepmc +1 more source
ABSTRACT Background This study examines the relationship between the microbial load of selected periodontitis‐associated bacteria (PAB) and proinflammatory biomarkers in gingival crevicular fluid (GCF) from patients with periodontitis. Methods GCF and subgingival biofilm samples were collected from the deepest periodontal pocket of each quadrant of 515
Nils Werner +9 more
wiley +1 more source

