Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine +4 more
wiley +1 more source
USP22 knockdown attenuates <i>P. gingivalis</i>-induced EndoMT and CNS inflammation: a link between periodontitis and neuroinflammation. [PDF]
Wang H, Wang M, Shen J, Zhang H, Duan C.
europepmc +1 more source
CKIP-1 mediates P. gingivalis-suppressed osteogenic/cementogenic differentiation of periodontal ligament cells partially via p38 signaling pathway. [PDF]
Huang X +7 more
europepmc +1 more source
Viruses, Periodontitis, and Systemic Diseases
This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte +2 more
wiley +1 more source
The Oral‐Hepatic Axis: Epidemiological and Mechanistic Links Between Periodontal and Liver Diseases
This review summarizes current epidemiological, clinical and mechanistic evidence linking periodontitis and chronic liver diseases, highlighting the oral‐gut‐liver axis, shared immunometabolic and nutritional pathways and opportunities for integrated preventive and therapeutic strategies.
Sinem Esra Sahingur +3 more
wiley +1 more source
Bacterial-host interactions in periodontal prognosis: Role of <i>P. gingivalis</i> and IL-8. [PDF]
Lin YC +4 more
europepmc +1 more source
P. gingivalis Infection Upregulates PD-L1 Expression on Dendritic Cells, Suppresses CD8+ T-cell Responses, and Aggravates Oral Cancer. [PDF]
Ren J +6 more
europepmc +1 more source
The Dual Face of Fusobacterium nucleatum in Cancer: Foe, Friend or Both?
Fusobacterium nucleatum has established interactions with cancers in humans. However, contrary to a traditional view that these interactions are uniformly pro‐tumoural, recent evidence suggests a more nuanced role, where contact‐dependent and contact‐independent mechanisms may support either tumour progression or restriction depending on tumour site ...
Anjali Chander +3 more
wiley +1 more source
Differential antimicrobial activity of two LL37 derivatives against periodontal bacteria, including enhanced efficacy against <i>P. gingivalis</i> in the presence of cigarette smoke. [PDF]
Keshavarz S, Hirschfeld J, Grant MM.
europepmc +1 more source
Continuous Oral Administration of Sonicated P. gingivalis Delays Rat Skeletal Muscle Healing Post-Treadmill Training. [PDF]
Hayashi K +6 more
europepmc +1 more source

