Results 31 to 40 of about 23,411 (243)

Functional Advantages of Porphyromonas gingivalis Vesicles. [PDF]

open access: yesPLoS ONE, 2015
Porphyromonas gingivalis is a keystone pathogen of periodontitis. Outer membrane vesicles (OMVs) have been considered as both offense and defense components of this bacterium. Previous studies indicated that like their originating cells, P.
Meng-Hsuan Ho   +4 more
doaj   +1 more source

Research Note: A novel method for preparation of egg yolk immunoglobulin Y against Porphyromonas gingivalis

open access: yesPoultry Science, 2023
: Porphyromonas gingivalis (P. gingivalis, P. g) is the main pathogen of periodontal disease, which is treated with egg yolk immunoglobulin Y (IgY) against P. gingivalis.
Han Su   +4 more
doaj   +1 more source

The efficacy of sarang semut extract (Myrmecodia pendens Merr & Perry) in inhibiting Porphyromonas gingivalis biofilm formation

open access: yesDental Journal, 2017
Background: Porphyromonas gingivalis (P. gingivalis) is a pathogenic bacteria present in the oral cavity involved in the pathogenesis of chronic periodontitis and biofilm.
Zulfan M. Alibasyah   +5 more
doaj   +1 more source

Assessment of antimicrobial efficacy of chitosan-based tetracycline gel on periodontal pathogens: An In vitro study

open access: yesJournal of Pharmacy and Bioallied Sciences, 2023
Aim: The aim of the current research was to evaluate the antimicrobial effectiveness of chitosan-based tetracycline gel on periodontal pathogenic microorganisms.
Mohammad Jalaluddin   +5 more
doaj   +1 more source

P. Gingivalils Induces Endothelial Dysfunction By mPTP Via Mitochondrial Fission

open access: yesInternational Dental Journal
Aim or purpose: To explore the important role of Drp1-VDAC1-HK2 axis in regulating mitochondrial permeability transition pore (mPTP) opening in Porphyromonas gingivalis (P. gingivalis)-induced endothelial dysfunction.
Yi Wang, Shengming Xu, Hanxin Que
doaj   +1 more source

Porphyromonas gingivalis Induces Apoptosis and Autophagy via ER Stress in Human Umbilical Vein Endothelial Cells

open access: yesMediators of Inflammation, 2018
It has been reported that periodontitis is associated with an increased risk of atherosclerosis. Accumulating evidence suggests that endothelial dysfunction is an early marker for atherosclerosis.
Masaaki Hirasawa, Tomoko Kurita-Ochiai
doaj   +1 more source

P. gingivalis accelerates gingival epithelial cell progression through the cell cycle [PDF]

open access: yesMicrobes and Infection, 2008
P. gingivalis, an opportunistic pathogen in periodontal disease, can reside within the epithelial cells that line the gingival crevice. A proteomic analysis revealed that infection of gingival epithelial cells with P. gingivalis induces broadly based changes in the level and phosphorylation status of proteins that exert multi-level control on the ...
Department of Preventive Dentistry, Osaka University Graduate School of Dentistry, Osaka, Japan ( host institution )   +7 more
openaire   +3 more sources

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

open access: yesAdvanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji   +8 more
wiley   +1 more source

Porphyromonas Gingivalis Survives In BMECs By Kgp Inhibiting Lysosomal Acidification

open access: yesInternational Dental Journal
Aim or purpose: This study aimed to investigate Porphyromonas gingivalis (P. gingivalis) persistence in human brain microvascular endothelial cells (BMECs), its impact on cellular lysosomal acidification and regulatory mechanisms, given that brain ...
Angu Li, Xiaolin Tang
doaj   +1 more source

Matrix Stiffness Governs Fibroblasts’ Regulation of Gingival Immune Homeostasis

open access: yesAdvanced Materials, EarlyView.
This study identifies a “mechano‐epigenetic” checkpoint in which matrix stiffness governs the immune responses of gingival fibroblasts. Using biomimetic hydrogels and human gingival explants, the studies revealed that restoring extracellular matrix stiffness actively suppresses inflammation via non‐canonical NF‐κB signaling and DNA methylation ...
Hardik Makkar   +5 more
wiley   +1 more source

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