Results 81 to 90 of about 23,411 (243)

Does timing of systemic antibiotics influence periodontal treatment outcomes? A randomized clinical trial

Journal of Periodontology, EarlyView.
Abstract Background The aim of this study is to determine whether the timing of metronidazole (MTZ) and amoxicillin (AMX) administration, relative to scaling and root planing (SRP), influences the clinical and microbiological outcomes of periodontal treatment.
Daiane Fermiano, Eduardo de Souza Oliveira, Maria Josefa Mestnik, Luciene C. Figueiredo, Takahiko Shiba, Shunsuke Matsumura, Edson de Sousa, Helio Doyle, Rafael Oliveira Dias, Marcelo de Faveri, Magda Feres   +10 more
wiley   +1 more source

Electrolyzed saline as an alternative to chlorhexidine: Antimicrobial and biofilm volume outcomes in a 4‐day non‐brushing randomized controlled clinical trial

Journal of Periodontology, EarlyView.
Abstract Background The biofilm‐inhibitory effects of electrolyzed saline (EOS) vary widely due to differences in formulations and treatment methods. This study analyzed the impact of EOS on key oral microbial species and used serial 3D‐intraoral scans to evaluate its effects on de novo biofilm formation.
Katja Povšič, Haris Munjaković, Naiera Zayed, Wim Teughels, Katja Seme, Aleš Fidler, Rok Gašperšič   +6 more
wiley   +1 more source

Combined Effects of Puerarin and Adipose‐Derived Stem Cells on Alveolar Bone Preservation and Inflammation Control in Periodontitis Through p38MAPK Modulation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study evaluated the effects of puerarin and adipose‐derived stem cells (ADSCs), alone or combined, on p38MAPK activity, alveolar bone preservation, and inflammatory responses in a rat periodontitis (PD) model and in vitro. ADSCs were exposed to various puerarin concentrations to assess cell proliferation, osteogenic differentiation, and ...
Ting Yang, Xu Zhang, Liang‐Fu Zhang
wiley   +1 more source

Colonization by Porphyromonas gingivalis in cervical squamous cell carcinomas promotes metastasis through FimA/CD151/ITGB1 signaling

Journal of Translational Medicine
Background Cervicovaginal microbiota dysbiosis has been implicated in the progression of cervical cancer. Recent studies have reported an increased abundance of Porphyromonas species in the vaginal microbiota of cervical cancer patients.
Xiuting Huang, Yuan Zhuang, Rui Wang, Jing Qu, Yuanyang Tan, Liang Li, Wenjun Pan, Huilong Nie, Kefeng Li, Yujing Lin, Liutong Yi, Xiaoyu Feng, Huimin Lan, Guangxue Wang, Xiantao Zeng, Zhenqi Jiang, De-Yun Wang, Yongkang Qiao, Yan Yan   +18 more
doaj   +1 more source

Molecular mechanisms of Porphyromonas gingivalis-host cell interaction on periodontal diseases

Japanese Dental Science Review, 2017
Porphyromonas gingivalis (P. gingivalis) is a major oral pathogen and associated with periodontal diseases including periodontitis and alveolar bone loss. In this review, we indicate that two virulence factors, which are hemoglobin receptor protein (HbR)
Masaaki Nakayama, Naoya Ohara
doaj   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

An Ultrasmall Strontium‐Loaded Polydopamine Nanoformulation for Near‐Infrared‐Enhanced Periodontitis Therapy via Photodynamic Gas‐Promoted Antibacterial and Bone Repair

Rare Metals, EarlyView.
ABSTRACT Periodontitis is a chronic infectious oral disease triggered by periodontopathogenic bacteria, resulting in the progressive inflammation and destruction of the tissues surrounding teeth. To achieve reprogramming of the infectious microenvironment for periodontitis therapy, a nanoformulation was proposed by loading polydopamine (PDA) with ...
Hao Liang, Yu Liang, Rubiao Qiu, Kunpeng Duan, Jiaxiao Li, Yan Liu, Xiaowen Li, Li Wang, Lingling Liang, Mingyang Jiang, Chenxi Wang, Guojiang Chen, Ming Gao, Xiaojie Li, Tao Qin   +14 more
wiley   +1 more source

Changes in the microbiome and metabolome in captive red kangaroos (Osphranter rufus) affected by macropod progressive periodontal disease

Australian Veterinary Journal, EarlyView.
Macropod progressive periodontal disease (MPPD) is a severe oral condition frequently observed in captive macropods, particularly red kangaroos (Osphranter rufus), yet its underlying biological features remain poorly understood. In this exploratory descriptive study, we investigated oral and fecal microbiomes and metabolomic profiles in captive red ...
Y Yoshimoto, N Nagata, R Inoue, Y Yamamoto, K Nagaoka   +4 more
wiley   +1 more source

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

Periodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis, Daniel Belstrøm, Sigrun Eick, Ulvi K. Gursoy, Anders Johansson, Eija Könönen   +5 more
wiley   +1 more source

Porphyromonas gingivalis suppresses invasion of Fusobacterium nucleatum into gingival epithelial cells

Journal of Oral Microbiology, 2017
Invasion of periodontal pathogens into periodontal tissues is an important step that can cause tissue destruction in periodontal diseases. Porphyromonas gingivalis is a keystone pathogen and its gingipains are key virulence factors.
Young-Jung Jung, Hye-Kyoung Jun, Bong-Kyu Choi   +2 more
doaj   +1 more source