Results 91 to 100 of about 4,512 (151)

p130Cas mediates the transforming properties of the anaplastic lymphoma kinase.

, 2005
Translocations of the anaplastic lymphoma kinase (ALK) gene have been described in anaplastic large-cell lymphomas (ALCLs) and in stromal tumors. The most frequent translocation, t(2;5), generates the fusion protein nucleophosmin (NPM)-ALK with intrinsic
Riera, L, Tarone, G, Mohammed, Shabaz, Shabaz Mohammed, Guido Tarone, Roberto Chiarle, Claudia Voena, Defilippi, Paola, Giorgio Palestro, Piva, R, Defilippi, P, Elisabetta Boeri Erba, Ambrogio, C, Ludovica Riera, Chiara Ambrogio, Carlotta Costa, Tarone, Guido, Hirsch, Emilio, Manazza, AD, Inghirami, G, Ole N. Jensen, Ambrogio, Chiara, Voena, C, fl., m., Mohammed, S, Erba, Elisabetta Boeri, Barberis, L, Emilio Hirsch, Piva, Roberto, Boeri Erba, E, Giorgio Inghirami, Hirsch, E, Roberto Piva, Voena, Claudia, Palestro, G, Costa, Carlotta, Barberis, Laura, Costa, C, Jensen, Ole Nørregaard; id_orcid, Chiarle, R, Manazza, Andrea D., Jensen, ON, Andrea D. Manazza, Laura Barberis, Paola Defilippi, Riera, Ludovica   +45 more
core   +1 more source

The search for novel interaction partners of SH3 domain of an adaptor protein p130Cas [PDF]

, 2012
Protein p130Cas is the major tyrosine phosphorylated protein in cells transformed by v-crk and v-src oncogenes. P130Cas plays an important role in invasiveness and metastasis of Src-transformed cells.
Gemperle, Jakub
core  

Retraction: SOX2 Enhances the Migration and Invasion of Ovarian Cancer Cells via Src Kinase. [PDF]

PLoS One, 2023
PLOS ONE Editors.
europepmc   +1 more source

Endothelial p130cas confers resistance to anti-angiogenesis therapy

Cell Reports, 2023
Yunfei Wen, Anca Chelariu-Raicu, Sujanitha Umamaheswaran, Alpa M. Nick, Elaine Stur, Pahul Hanjra, Dahai Jiang, Nicholas B. Jennings, Xiuhui Chen, Sara Corvigno, Deanna Glassman, Gabriel Lopez-Berestein, Jinsong Liu, Mien-Chie Hung, Anil K. Sood   +14 more
doaj   +1 more source

VEGF promotes assembly of the p130Cas interactome to drive endothelial chemotactic signalling and angiogenesis [PDF]

, 2017
p130Cas is a polyvalent adapter protein essential for cardiovascular development, and with a key role in cell movement. In order to identify the pathways by which p130Cas exerts its biological functions in endothelial cells we mapped the p130Cas ...
Paliashvili, K, Zachary, IC, Frankel, P, Kennedy, SA, Santra, T, Evans, IM, Britton, G, Kolch, W, Yamaji, M, Lovering, RC   +9 more
core  

Evaluation of SgK269 expression in colon cancer patients and the effects of hAMSCs secretome on tumor invasion through SgK269/c-Src/p-P130Cas/p-Paxillin/p-ERK1/2 signaling pathway in HT-29 colon cancer cells. [PDF]

3 Biotech, 2023
Safari F, Ansari Dogaheh F, Dadashi H.
europepmc   +1 more source

The focal adhesion localization of p130Cas: dynamics, targeting mechanism, and signaling.

, 2010
Focal adhesions (FAs) are sites at the interface between the cell and the ECM, linking integrin receptors and the actin cytoskeleton. In addition to serving as a structural platform, these sites are also robust sites of tyrosine phosphorylation and ...
Donato, Dominique Maria
core  

The Role of Cysteine-Rich Protein 2 in Aortic Dissection: Implications for VSMC Phenotypic Modulation-CSRP2 Impedes the Progression of Aortic Dissection. [PDF]

Biomolecules
Liu C, Wang X, An C, Ge S, Zhang C.
europepmc   +1 more source

Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition. [PDF]

Cell Rep
Waters AM, Khatib TO, Papke B, Goodwin CM, Hobbs GA, Diehl JN, Yang R, Edwards AC, Walsh KH, Sulahian R, McFarland JM, Kapner KS, Gilbert TSK, Stalnecker CA, Javaid S, Barkovskaya A, Grover KR, Hibshman PS, Blake DR, Schaefer A, Nowak KM, Klomp JE, Hayes TK, Kassner M, Tang N, Tanaseichuk O, Chen K, Zhou Y, Kalkat M, Herring LE, Graves LM, Penn LZ, Yin HH, Aguirre AJ, Hahn WC, Cox AD, Der CJ.   +36 more
europepmc   +1 more source

An adhesion signaling axis involving Dystroglycan, β1-Integrin, and Cas adaptor proteins regulates the establishment of the cortical glial scaffold. [PDF]

PLoS Biol, 2023
Wong W, Estep JA, Treptow AM, Rajabli N, Jahncke JN, Ubina T, Wright KM, Riccomagno MM.   +7 more
europepmc   +1 more source