Results 81 to 90 of about 4,512 (151)
Cell Reports, 2015 In contrast to the accepted pro-proliferative effect of cell-matrix adhesion, the proliferative effect of cadherin-mediated cell-cell adhesion remains unresolved. Here, we studied the effect of N-cadherin on cell proliferation in the vasculature. We show
Keeley L. Mui +7 more
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Recent advances in angiotensin II signaling
Brazilian Journal of Medical and Biological Research, 2002 Angiotensin II (Ang II)* is a multifunctional hormone that influences the function of cardiovascular cells through a complex series of intracellular signaling events initiated by the interaction of Ang II with AT1 and AT2 receptors.
R.M. Touyz, C. Berry
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p130Cas/BCAR1 scaffold protein in tissue homeostasis and pathogenesis [PDF]
, 2015 BCAR1 (also known as p130Cas/BCAR1) is an adaptor protein that belongs to the CAS family of scaffold proteins. In the past years, increasing evidence has demonstrated the ability of p130Cas/BCAR1 to activate signaling originating from mechanical stimuli,
Tornillo, Giusy +6 more
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Conditional deletion of CD98hc inhibits osteoclast development
Biochemistry and Biophysics Reports, 2016 The CD98 heavy chain (CD98hc) regulates virus-induced cell fusion and monocyte fusion, and is involved in amino acid transportation. Here, we examined the role that CD98hc plays in the formation of osteoclasts using CD98hcflox/floxLysM-cre peritoneal ...
Hideki Tsumura +10 more
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Vliv fosforylace p130CAS na Ser/Thr zbytcích na signalizaci
, 2014 p130Cas je dôležitý adaptorový proteín, zohrávajúci kľúčovú úlohu v mnohých bunkových signálnych procesoch. Keďže p130Cas je známym substrátom pre široké spektrum kináz, jeho funkcia je regulovaná predovšetkým zmenami vo fosforylácii na tyrozínových ...
Dibus, Michal
core
Immunohistochemical expression of p130cas in papillary thyroid carcinoma
, 2008 p130cas is a multifunctional protein that is involved in many aspects of cellular physiology, including adhesion, migration, and regulation of the cell cycle, and can be regulated by a variety of stimuli.
Dilek, Osman Nuri +4 more
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Nature Communications, 2015 Epstein–Barr virus (EBV), aetiologically linked to nasopharyngeal carcinoma (NPC), is the first human virus found to encode many miRNAs. However, how these viral miRNAs precisely regulate the tumour metastasis in NPC remains obscure.
Longmei Cai +11 more
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The Role of p130Cas Signaling Domains in Cell Migraion
, 2010 The docking protein p130Cas is a prominent Src substrate found in focal adhesions (FAs) and is implicated in regulating critical aspects of cell motility including FA disassembly and protrusion of the leading edge plasma membrane.
Meenderink, Leslie M.
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The role of p130CAS in integrin signaling
, 2014 Focal adhesions are important subcellular structures that are composed of many signaling and scaffolding proteins. They serve not only for anchoring the cell to the substratum but they are also important signaling centers that regulate various cellular ...
Janoštiak, Radoslav
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The role of Ser/Thr phosphorylation of p130CAS in signaling
, 2014 p130Cas is an important adaptor protein that plays an essential role in many intracellular signaling processes. Given the fact that p130Cas is a well-known substrate for wide spectrum of kinases, its function is regulated mostly by phosphorylation on ...
Dibus, Michal
core